The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Authors
Keywords
-
Journal
CARDIOVASCULAR RESEARCH
Volume 109, Issue 4, Pages 467-479
Publisher
Oxford University Press (OUP)
Online
2015-12-25
DOI
10.1093/cvr/cvv275
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Role of Pharmacogenetics in Atrial Fibrillation Therapeutics
- (2016) Dawood Darbar JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The pioneering work of George Mines on cardiac arrhythmias: groundbreaking ideas that remain influential in contemporary cardiac electrophysiology
- (2016) Martin Aguilar et al. JOURNAL OF PHYSIOLOGY-LONDON
- Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation
- (2015) Edward Glasscock et al. BASIC RESEARCH IN CARDIOLOGY
- Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation
- (2015) Jordi Heijman et al. BASIC RESEARCH IN CARDIOLOGY
- Arrhythmia causes lipid accumulation and reduced glucose uptake
- (2015) Matthias Lenski et al. BASIC RESEARCH IN CARDIOLOGY
- LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation
- (2015) Grace E. Kim et al. CARDIOVASCULAR RESEARCH
- Potassium Channel Blockade Enhances Atrial Fibrillation–Selective Antiarrhythmic Effects of Optimized State-Dependent Sodium Channel BlockadeCLINICAL PERSPECTIVE
- (2015) Martin Aguilar et al. CIRCULATION
- Upregulation of K2P3.1 K+Current Causes Action Potential Shortening in Patients With Chronic Atrial FibrillationCLINICAL PERSPECTIVE
- (2015) Constanze Schmidt et al. CIRCULATION
- The HARMONY Trial
- (2015) James A. Reiffel et al. Circulation-Arrhythmia and Electrophysiology
- Improving clinical trials for cardiovascular diseases: a position paper from the Cardiovascular Round Table of the European Society of Cardiology
- (2015) Neville Jackson et al. EUROPEAN HEART JOURNAL
- Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts
- (2015) Brian J. Hansen et al. EUROPEAN HEART JOURNAL
- Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue
- (2015) Michael B. Liu et al. HEART RHYTHM
- The Past, Present, and Potential Future of Sodium Channel Block as an Atrial Fibrillation Suppressing Strategy
- (2015) Martin Aguilar et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics
- (2015) Jordi Heijman et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation
- (2015) Jordi Heijman et al. JOURNAL OF PHYSIOLOGY-LONDON
- Atrial Fibrillation Activates AMP-Dependent Protein Kinase and its Regulation of Cellular Calcium Handling
- (2015) Masahide Harada et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Cardiac Fibrosis in Patients With Atrial Fibrillation
- (2015) Mikhail S. Dzeshka et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Low-Level Transcutaneous Electrical Vagus Nerve Stimulation Suppresses Atrial Fibrillation
- (2015) Stavros Stavrakis et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Adenosine-guided pulmonary vein isolation for the treatment of paroxysmal atrial fibrillation: an international, multicentre, randomised superiority trial
- (2015) Laurent Macle et al. LANCET
- Approaches to Catheter Ablation for Persistent Atrial Fibrillation
- (2015) Atul Verma et al. NEW ENGLAND JOURNAL OF MEDICINE
- Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success
- (2015) Eue‐Keun Choi et al. Journal of the American Heart Association
- The Role of Tissue Engineering and Biomaterials in Cardiac Regenerative Medicine
- (2014) Yimu Zhao et al. CANADIAN JOURNAL OF CARDIOLOGY
- New Directions in Cardiac Arrhythmia Management: Present Challenges and Future Solutions
- (2014) Stanley Nattel et al. CANADIAN JOURNAL OF CARDIOLOGY
- Association of metformin with lower atrial fibrillation risk among patients with type 2 diabetes mellitus: a population-based dynamic cohort and in vitro studies
- (2014) Shang-Hung Chang et al. Cardiovascular Diabetology
- Driver Domains in Persistent Atrial Fibrillation
- (2014) Michel Haissaguerre et al. CIRCULATION
- Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model
- (2014) Na Li et al. CIRCULATION
- Atrial Fibrillation Compendium
- (2014) Kunihiro Nishida et al. CIRCULATION RESEARCH
- Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression
- (2014) Jordi Heijman et al. CIRCULATION RESEARCH
- The Clinical Profile and Pathophysiology of Atrial Fibrillation
- (2014) Jason Andrade et al. CIRCULATION RESEARCH
- Role of the Autonomic Nervous System in Atrial Fibrillation
- (2014) Peng-Sheng Chen et al. CIRCULATION RESEARCH
- Loss of MicroRNA-106b-25 Cluster Promotes Atrial Fibrillation by Enhancing Ryanodine Receptor Type-2 Expression and Calcium Release
- (2014) David Y. Chiang et al. Circulation-Arrhythmia and Electrophysiology
- Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes
- (2014) Maura Greiser et al. JOURNAL OF CLINICAL INVESTIGATION
- Atrial Fibrillation Ablation
- (2014) Kunihiro Nishida et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Atrial Fibrillation Promotion With Long-Term Repetitive Obstructive Sleep Apnea in a Rat Model
- (2014) Yu-ki Iwasaki et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- MicroRNAs and atrial fibrillation: mechanisms and translational potential
- (2014) Xiaobin Luo et al. Nature Reviews Cardiology
- Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation
- (2014) T. Christ et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computational Models of Ventricular- and Atrial-Like Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
- (2013) Michelangelo Paci et al. ANNALS OF BIOMEDICAL ENGINEERING
- Paroxysmal Atrial Fibrillation and Pulmonary Veins: Relationships Between Clinical Forms and Automatic Versus Re-entrant Mechanisms
- (2013) Stanley Nattel CANADIAN JOURNAL OF CARDIOLOGY
- Atrial supply–demand balance in healthy adult pigs: coronary blood flow, oxygen extraction, and lactate production during acute atrial fibrillation
- (2013) Kelly A. van Bragt et al. CARDIOVASCULAR RESEARCH
- Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation
- (2013) James H. King et al. CARDIOVASCULAR RESEARCH
- Role of Small-Conductance Calcium-Activated Potassium Channels in Atrial Electrophysiology and Fibrillation in the Dog
- (2013) Xiao-Yan Qi et al. CIRCULATION
- Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation
- (2013) Niels Voigt et al. CIRCULATION
- Transmural Conduction Is the Predominant Mechanism of Breakthrough During Atrial Fibrillation
- (2013) Jens Eckstein et al. Circulation-Arrhythmia and Electrophysiology
- Personalized management of atrial fibrillation: Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference
- (2013) P. Kirchhof et al. EUROPACE
- Effect of Weight Reduction and Cardiometabolic Risk Factor Management on Symptom Burden and Severity in Patients With Atrial Fibrillation
- (2013) Hany S. Abed et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation
- (2013) Xiaobin Luo et al. JOURNAL OF CLINICAL INVESTIGATION
- The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential
- (2013) Christophe Simard et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A proposal for new clinical concepts in the management of atrial fibrillation
- (2012) A. John Camm et al. AMERICAN HEART JOURNAL
- In Silico Optimization of Atrial Fibrillation-Selective Sodium Channel Blocker Pharmacodynamics
- (2012) Martin Aguilar-Shardonofsky et al. BIOPHYSICAL JOURNAL
- Transient Receptor Potential Canonical-3 Channel–Dependent Fibroblast Regulation in Atrial Fibrillation
- (2012) Masahide Harada et al. CIRCULATION
- Enhanced Sarcoplasmic Reticulum Ca 2+ Leak and Increased Na + -Ca 2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation
- (2012) Niels Voigt et al. CIRCULATION
- MK-0448, a Specific Kv1.5 Inhibitor
- (2012) Behzad B. Pavri et al. Circulation-Arrhythmia and Electrophysiology
- Concomitant obstructive sleep apnea increases the recurrence of atrial fibrillation following radiofrequency catheter ablation of atrial fibrillation: Clinical impact of continuous positive airway pressure therapy
- (2012) Yoshihisa Naruse et al. HEART RHYTHM
- Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation
- (2012) Hany S. Abed et al. HEART RHYTHM
- Symptomatic Response to Antiarrhythmic Drug Therapy Is Modulated by a Common Single Nucleotide Polymorphism in Atrial Fibrillation
- (2012) Babar Parvez et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Treatment of Atrial Fibrillation by the Ablation of Localized Sources
- (2012) Sanjiv M. Narayan et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Novel molecular targets for atrial fibrillation therapy
- (2012) Dobromir Dobrev et al. NATURE REVIEWS DRUG DISCOVERY
- Continuous Low-Level Vagus Nerve Stimulation Reduces Stellate Ganglion Nerve Activity and Paroxysmal Atrial Tachyarrhythmias in Ambulatory Canines
- (2011) Mark J. Shen et al. CIRCULATION
- Atrial Fibrillation Pathophysiology
- (2011) Yu-ki Iwasaki et al. CIRCULATION
- Connexins and Atrial Fibrillation
- (2011) Takeshi Kato et al. CIRCULATION
- Upstream therapies for management of atrial fibrillation: review of clinical evidence and implications for European Society of Cardiology guidelines. Part I: primary prevention
- (2011) I. Savelieva et al. EUROPACE
- Upstream therapies for management of atrial fibrillation: review of clinical evidence and implications for European Society of Cardiology guidelines. Part II: secondary prevention
- (2011) I. Savelieva et al. EUROPACE
- Rapid pulmonary vein isolation combined with autonomic ganglia modification: A randomized study
- (2011) Demosthenes G. Katritsis et al. HEART RHYTHM
- Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release
- (2011) Qiang Zhou et al. NATURE MEDICINE
- Dronedarone in Atrial Fibrillation — Jekyll and Hyde?
- (2011) Stanley Nattel NEW ENGLAND JOURNAL OF MEDICINE
- Dronedarone in High-Risk Permanent Atrial Fibrillation
- (2011) Stuart J. Connolly et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms by Which Adenosine Restores Conduction in Dormant Canine Pulmonary Veins
- (2010) Tomás Datino et al. CIRCULATION
- Noninvasive Characterization of Epicardial Activation in Humans With Diverse Atrial Fibrillation Patterns
- (2010) Phillip S. Cuculich et al. CIRCULATION
- Gender in atrial fibrillation: Ten years later
- (2010) Hector I. Michelena et al. Gender Medicine
- Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure
- (2010) Ayesha I. De Souza et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Synergistic Effect of the Combination of Ranolazine and Dronedarone to Suppress Atrial Fibrillation
- (2010) Alexander Burashnikov et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- New antiarrhythmic drugs for treatment of atrial fibrillation
- (2010) Dobromir Dobrev et al. LANCET
- Prevention of Atrial Fibrillation
- (2009) Emelia J. Benjamin et al. CIRCULATION
- Novel Approaches for Pharmacological Management of Atrial Fibrillation
- (2009) Joachim R. Ehrlich et al. DRUGS
- Animal models for atrial fibrillation: clinical insights and scientific opportunities
- (2009) K. Nishida et al. EUROPACE
- Effect of Dronedarone on Cardiovascular Events in Atrial Fibrillation
- (2009) Stefan H. Hohnloser et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanisms of atrial fibrillation termination by rapidly unbinding Na+ channel blockers: insights from mathematical models and experimental correlates
- (2008) Philippe Comtois et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Differential Behaviors of Atrial Versus Ventricular Fibroblasts
- (2008) Brett Burstein et al. CIRCULATION
- Pulmonary Vein Region Ablation in Experimental Vagal Atrial Fibrillation
- (2008) Kristina Lemola et al. CIRCULATION
- Atrial Remodeling and Atrial Fibrillation
- (2008) Stanley Nattel et al. Circulation-Arrhythmia and Electrophysiology
- Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation
- (2008) Manuel Mayr et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Increased Mortality after Dronedarone Therapy for Severe Heart Failure
- (2008) Lars Køber et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started