The role of inflammatory biomarkers in developing targeted cardiovascular therapies: lessons from the cardiovascular inflammation reduction trials

Aspirin-induced histone acetylation in endothelial cells enhances synthesis of the secreted isoform of netrin-1 thus inhibiting monocyte vascular infiltration

(2015) Gabriella Passacquale et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipid profile changes in patients with rheumatic diseases receiving a treatment with TNF-α blockers: A meta-analysis of prospective studies

(2014) Matteo Nicola Dario Di Minno et al.   ANNALS OF MEDICINE

Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes

(2014) Siroon Bekkering et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Small high-density lipoprotein is associated with monocyte subsets in stable coronary artery disease

(2014) Konstantin A. Krychtiuk et al.   ATHEROSCLEROSIS

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study

(2014) A. C. Morton et al.   EUROPEAN HEART JOURNAL

Anti-inflammatory therapies for cardiovascular disease

(2014) P. M. Ridker et al.   EUROPEAN HEART JOURNAL

Gevokizumab in type 1 diabetes mellitus: extreme remedies for extreme diseases?

(2014) Kalliopi Pafili et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome

(2014) Michelle L. O’Donoghue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome

(2014) Stephen J. Nicholls et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes

(2014) André J. Tremblay et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory biomarkers for predicting cardiovascular disease

(2013) Lee Stoner et al.   CLINICAL BIOCHEMISTRY

Monocytes in Coronary Artery Disease and Atherosclerosis

(2013) Angie Ghattas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Role of Oxidized Low-Density Lipoproteins in Atherosclerosis: The Myths and the Facts

(2013) Giuseppe Maiolino et al.   MEDIATORS OF INFLAMMATION

Effect of TNF inhibitors on lipid profile in rheumatoid arthritis: a systematic review with meta-analysis

(2012) Claire Immediato Daïen et al.   ANNALS OF THE RHEUMATIC DISEASES

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Effects of Interleukin-1β Inhibition With Canakinumab on Hemoglobin A1c, Lipids, C-Reactive Protein, Interleukin-6, and Fibrinogen

(2012) Paul M Ridker et al.   CIRCULATION

Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

(2012) C. Cavelti-Weder et al.   DIABETES CARE

CD14++CD16+ Monocytes Independently Predict Cardiovascular Events

(2012) Kyrill S. Rogacev et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

(2012) Janine M van Gils et al.   NATURE IMMUNOLOGY

CD8+ T Cells Mediate the Athero-Protective Effect of Immunization with an ApoB-100 Peptide

(2012) Kuang-Yuh Chyu et al.   PLoS One

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: Rationale and Design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

(2011) Paul M Ridker et al.   AMERICAN HEART JOURNAL

Oxidized Low-Density Lipoprotein and Atherosclerosis Implications in Antioxidant Therapy

(2011) Sona Mitra et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

CD14 dim CD16 + and CD14 + CD16 + Monocytes in Obesity and During Weight Loss

(2011) Christine Poitou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heat Shock Protein 60 and Immune Inflammatory Responses in Atherosclerosis

(2011) Cecilia Grundtman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial

(2011) P. S. Sever et al.   EUROPEAN HEART JOURNAL

Monocyte-Platelet Interaction Induces a Pro-Inflammatory Phenotype in Circulating Monocytes

(2011) Gabriella Passacquale et al.   PLoS One

Prognostic value of high-sensitivity C-reactive protein in a population of post-acute coronary syndrome patients receiving optimal medical treatment

(2011) Mélanie Riedel et al.   European Journal of Preventive Cardiology

Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris

(2010) Toshio Imanishi et al.   ATHEROSCLEROSIS

Association of monocyte subsets with vulnerability characteristics of coronary plaques as assessed by 64-slice multidetector computed tomography in patients with stable angina pectoris

(2010) Manabu Kashiwagi et al.   ATHEROSCLEROSIS

Treatment With 5-Lipoxygenase Inhibitor VIA-2291 (Atreleuton) in Patients With Recent Acute Coronary Syndrome

(2010) Jean-Claude Tardif et al.   Circulation-Cardiovascular Imaging

Randomized trial of an inhibitor of secretory phospholipase A2 on atherogenic lipoprotein subclasses in statin-treated patients with coronary heart disease

(2010) Robert S. Rosenson et al.   EUROPEAN HEART JOURNAL

CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease

(2010) Kyrill S. Rogacev et al.   EUROPEAN HEART JOURNAL

Co-administration of a CpG adjuvant (VaxImmuneTM, CPG 7909) with CETP vaccines increased immunogenicity in rabbits and mice

(2010) Lawrence J. Thomas et al.   Human vaccines & immunotherapeutics

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

(2010) Jérôme Cros et al.   IMMUNITY

Effects of Varespladib Methyl on Biomarkers and Major Cardiovascular Events in Acute Coronary Syndrome Patients

(2010) Robert S. Rosenson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Macrophage Plasticity in Experimental Atherosclerosis

(2010) Jamila Khallou-Laschet et al.   PLoS One

Comparison of gene expression profiles between human and mouse monocyte subsets

(2009) M. A. Ingersoll et al.   BLOOD

Future Role for Selective Phospholipase A2 Inhibitors in the Prevention of Atherosclerotic Cardiovascular Disease

(2009) Robert S. Rosenson   CARDIOVASCULAR DRUGS AND THERAPY

Rosiglitazone Decreases C-Reactive Protein to a Greater Extent Relative to Glyburide and Metformin Over 4 Years Despite Greater Weight Gain: Observations from A Diabetes Outcome Progression Trial (ADOPT)

(2009) S. E. Kahn et al.   DIABETES CARE

Monocyte heterogeneity in obesity and subclinical atherosclerosis

(2009) K. S. Rogacev et al.   EUROPEAN HEART JOURNAL

C-reactive protein among community-dwelling hypertensives on single-agent antihypertensive treatment

(2009) Tibor Fulop et al.   Journal of the American Society of Hypertension

Effects of 1-H-indole-3-glyoxamide (A-002) on concentration of secretory phospholipase A2 (PLASMA study): a phase II double-blind, randomised, placebo-controlled trial

(2009) Robert S Rosenson et al.   LANCET

Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque

(2008) Patrick W. Serruys et al.   CIRCULATION

Different functions of monocyte subsets in familial hypercholesterolemia: potential function of CD14+CD16+ monocytes in detoxification of oxidized LDL

(2008) Sandy Mosig et al.   FASEB JOURNAL

Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts

(2008) Tina Shah et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent

(2008) Emile R. Mohler et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial

(2008) Jean-Claude Tardif et al.   LANCET

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of the antioxidant succinobucol (AGI-1067) on human atherosclerosis in a randomized clinical trial

(2007) Jean-Claude Tardif et al.   ATHEROSCLEROSIS

CD14++CD16+ monocytes but not total monocyte numbers predict cardiovascular events in dialysis patients

(2007) G.H. Heine et al.   KIDNEY INTERNATIONAL