SRT1720 counteracts glucosamine-induced endoplasmic reticulum stress and endothelial dysfunction

Exendin-4 attenuates endoplasmic reticulum stress through a SIRT1-dependent mechanism

(2014) Jinmi Lee et al.   CELL STRESS & CHAPERONES

The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet

(2014) Sarah J. Mitchell et al.   Cell Reports

Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications

(2014) Dmitry A. Chistiakov et al.   Biomed Research International

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

Lost in translation: endoplasmic reticulum stress and the decline ofβ-cell health in diabetes mellitus

(2013) C. Evans-Molina et al.   DIABETES OBESITY & METABOLISM

N-Linked Glycosylation Supports Cross-Talk between Receptor Tyrosine Kinases and Androgen Receptor

(2013) Harri M. Itkonen et al.   PLoS One

Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1

(2013) R Ghemrawi et al.   Cell Death & Disease

The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease

(2012) Natasha E. Zachara   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150

(2012) Tae Woo Jung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Blockade of the Nuclear Factor-κB Pathway in the Endothelium Prevents Insulin Resistance and Prolongs Life Spans

(2012) Yutaka Hasegawa et al.   CIRCULATION

Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE−/− mice

(2011) Daniel R. Beriault et al.   ATHEROSCLEROSIS

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Multiple Site Acetylation of Rictor Stimulates Mammalian Target of Rapamycin Complex 2 (mTORC2)-dependent Phosphorylation of Akt Protein

(2011) Emily J. Glidden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Over-expression of mitogen-activated protein kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells

(2010) Mashael Al-Mutairi et al.   BRITISH JOURNAL OF PHARMACOLOGY

The paradoxical world of protein O-GlcNAcylation: a novel effector of cardiovascular (dys)function

(2010) S. A. Marsh et al.   CARDIOVASCULAR RESEARCH

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183

(2010) Julie L Huber et al.   Future Medicinal Chemistry

SIRT1 Activation by Small Molecules

(2010) Han Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

(2010) Michelle Pacholec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum stress and atherosclerosis

(2010) Gökhan S Hotamisligil   NATURE MEDICINE

O-linked β-N-acetylglucosamine During Hyperglycemia Exerts Both Anti-Inflammatory and Pro-Oxidative Properties in the Endothelial System

(2010) Angana Gupta Rajapakse et al.   Oxidative Medicine and Cellular Longevity

SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

(2010) Hiyaa Singhee Ghosh et al.   PLoS One

O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death

(2009) Gladys A. Ngoh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model

(2009) Mohammad I. Khan et al.   ANTIOXIDANTS & REDOX SIGNALING

Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis

(2009) Mete Civelek et al.   CIRCULATION RESEARCH

Molecular convergence of hexosamine biosynthetic pathway and ER stress leading to insulin resistance in L6 skeletal muscle cells

(2009) V. Srinivasan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

(2009) Ebru Erbay et al.   NATURE MEDICINE

Glucose Amplifies Fatty Acid-Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells via Activation of mTORC1

(2009) Etti Bachar et al.   PLoS One

Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system

(2008) Boglarka Laczy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism