ERK-dependent mTOR pathway is involved in berberine-induced autophagy in hepatic steatosis

mTOR remains unchanged in diet-resistant (DR) rats despite impaired LKB1/AMPK cascade in adipose tissue

(2016) Jie Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

(2016) Jayalakshmi Lakshmipathi et al.   DIABETES

TLR9-ERK-mTOR signaling is critical for autophagic cell death induced by CpG oligodeoxynucleotide 107 combined with irradiation in glioma cells

(2016) Xiaoli Li et al.   Scientific Reports

Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity

(2016) Ting Guo et al.   Scientific Reports

Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress

(2016) Zhiguo Zhang et al.   Scientific Reports

Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status

(2015) Jiaqi Lu et al.   EXPERIMENTAL CELL RESEARCH

C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress

(2015) Tae Woo Jung et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease

(2015) Hong-Mei Yan et al.   PLoS One

Berberine inhibits LPS-induced TF procoagulant activity and expression through NF-κB/p65, Akt and MAPK pathway in THP-1 cells

(2014) Meng-yu Gao et al.   Pharmacological Reports

Autophagy and Non-Alcoholic Fatty Liver Disease

(2014) Vanessa J. Lavallard et al.   Biomed Research International

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2

(2014) Birgit Knebel et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD

(2013) Di Ma et al.   MOLECULAR ENDOCRINOLOGY

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

(2012) Kook Hwan Kim et al.   NATURE MEDICINE

Structural Changes of Gut Microbiota during Berberine-Mediated Prevention of Obesity and Insulin Resistance in High-Fat Diet-Fed Rats

(2012) Xu Zhang et al.   PLoS One

Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver

(2011) Lian-Jun Xing et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis

(2010) Dina G. Tiniakos et al.   Annual Review of Pathology-Mechanisms of Disease

Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism

(2010) Ning Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity

(2009) Woo Sik Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Berberine modulates insulin signaling transduction in insulin-resistant cells

(2009) Li-Zhong Liu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL