The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains

Published 2016 View Full Article

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Title
The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains
Authors
Keywords
AL amyloidosis, systemic amyloidosis, amyloid fibrils, endoproteolysis, immunoglobulin
Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 428, Issue 21, Pages 4280-4297
Publisher
Elsevier BV
Online
2016-08-31
DOI
10.1016/j.jmb.2016.08.021

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