Dose Adjustment of Concomitant Antiseizure Medications During Cenobamate Treatment: Expert Opinion Consensus Recommendations

The ups and downs of alkyl‐carbamates in epilepsy therapy: How does cenobamate differ?

(2021) Wolfgang Löscher et al.   EPILEPSIA

Efficacy and safety of cenobamate in patients with uncontrolled focal seizures: A meta‐analysis

(2021) Lanlan Zhang et al.   ACTA NEUROLOGICA SCANDINAVICA

Pharmacology of Cenobamate: Mechanism of Action, Pharmacokinetics, Drug–Drug Interactions and Tolerability

(2021) Roberta Roberti et al.   CNS DRUGS

The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

(2021) Anthony Marson et al.   LANCET

Effect of cenobamate on the single‐dose pharmacokinetics of multiple cytochrome P450 probes using a cocktail approach in healthy subjects

(2021) Stephen A. Greene et al.   CTS-Clinical and Translational Science

Post hoc analysis of a phase 3, multicenter, open‐label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications

(2021) William E. Rosenfeld et al.   EPILEPSIA

Expert Opinion: Managing sleep disturbances in people with epilepsy

(2021) Lino Nobili et al.   EPILEPSY & BEHAVIOR

Cenobamate: First Approval

(2020) Susan J. Keam   DRUGS

Tolerability of Antiseizure Medications in Individuals With Newly Diagnosed Epilepsy

(2020) Bshra Ali A. Alsfouk et al.   JAMA Neurology

Pharmacokinetics of Cenobamate: Results From Single and Multiple Oral Ascending‐Dose Studies in Healthy Subjects

(2020) Laurent Vernillet et al.   Clinical Pharmacology in Drug Development

Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open‐label safety study

(2020) Michael R. Sperling et al.   EPILEPSIA

Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures

(2020) Steve S. Chung et al.   NEUROLOGY

A pragmatic algorithm to select appropriate antiseizure medications in patients with epilepsy

(2020) Ali A. Asadi‐Pooya et al.   EPILEPSIA

Positive allosteric modulation of GABAA receptors by a novel antiepileptic drug cenobamate

(2020) Ramesh Sharma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Adjunctive Cenobamate for Focal-Onset Seizures in Adults: A Systematic Review and Meta-Analysis

(2020) Simona Lattanzi et al.   CNS DRUGS

Cenobamate (XCOPRI): Can preclinical and clinical evidence provide insight into its mechanism of action?

(2020) Michelle Guignet et al.   EPILEPSIA

European Expert Opinion on ANT-DBS therapy for patients with drug-resistant epilepsy (a Delphi consensus)

(2020) Elisabeth Kaufmann et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Effects of cenobamate (YKP3089), a newly developed anti-epileptic drug, on voltage-gated sodium channels in rat hippocampal CA3 neurons

(2019) Michiko Nakamura et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Drug–drug interactions and pharmacodynamics of concomitant clobazam and cannabidiol or stiripentol in refractory seizures

(2019) Pavel Klein et al.   EPILEPSY & BEHAVIOR

Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial

(2019) Gregory L Krauss et al.   LANCET NEUROLOGY

Cannabinoids for epilepsy: What do we know and where do we go?

(2017) Martin J. Brodie et al.   EPILEPSIA

Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy

(2015) Alexandra L. Geffrey et al.   EPILEPSIA

Effect of reduction of antiepileptic drugs in patients with drug-refractory epilepsy

(2015) Deepa Dash et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Antiepileptic activity of preferential inhibitors of persistent sodium current

(2014) Lyndsey L. Anderson et al.   EPILEPSIA

Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review

(2013) Stephen M. Stout et al.   DRUG METABOLISM REVIEWS

Determinants of health-related quality of life in pharmacoresistant epilepsy: Results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments

(2011) Chiara Luoni et al.   EPILEPSIA

Truly “Rational” Polytherapy: Maximizing Efficacy and Minimizing Drug Interactions, Drug Load, and Adverse Effects

(2009) Erik St. Louis   Current Neuropharmacology

Transitional Polytherapy: Tricks of the Trade for Monotherapy to Monotherapy AED Conversions

(2009) William Garnett et al.   Current Neuropharmacology