4.4 Article

Repairing tendon-exposed wounds by combing the Masquelet technique with dermoplasty

Journal

FRONTIERS IN SURGERY
Volume 9, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fsurg.2022.995316

Keywords

exposed tendon; wounds; skin grafting; Masquelet; gentamicin bone cement

Categories

Funding

  1. Hainan Province Clinical Medical Center
  2. Hainan Provincial Natural Science Foundation of China
  3. Hainan Province Science and Technology Special Fund [822MS174, 822QN463]
  4. National Natural Science Foundation of China [ZDYF2021SHFZ238, ZDKJ2021038]
  5. Hainan Provincial Health and Family Planning Commission Project [81860347]
  6. Youth cultivation fund of the First Affiliated Hospital of Hainan Medical University [21A200231, 21A200062]
  7. Hainan Medical College 2022 Student Innovation and Entrepreneurship Training Program [HYFYPY2005]
  8. [X202211810008]

Ask authors/readers for more resources

The study found that the Masquelet technique can effectively treat exposed tendon wounds with lower cost and simpler care methods. Direct skin grafting achieved success in most patients by forming an induction membrane.
BackgroundWound repair is a new field that has emerged in China in the last 5 years. Exposed tendon wounds are one of the most common problems faced in wound treatment today, as the poor blood supply leads to low survival rates of skin grafts. This paper explores the feasibility of applying the Masquelet technique to repair tendon-exposed wounds. MethodWe examined 12 patients with tendon-exposed wounds, 5 males and 7 females, from January 2021 to November 2021, including 2 patients with post-traumatic wounds, 8 diabetic patients with dorsal wounds, and 2 patients with various chronic infections. The Masquelet technique was employed to treat these wounds. The wound surface was sealed with antibiotic bone cement to form an induction membrane, the cement was removed after 3-4 weeks, and the wound was repaired with skin grafts to observe survival, appearance, texture, healing, and related functions. ResultsAll wounds were covered with antibiotic bone cement, and after 3-4 weeks, an induction membrane was applied, and in 10 out of 12 patients, full-thickness skin grafts were applied, and the patients survived. However, in 2 patients, the skin became partially necrotic, but these patients recovered by changing medications. ConclusionThe current study found that direct skin grafting may effectively treat exposed tendon wounds once the Masquelet approach generates the induction membrane. Further, this method is less difficult, less expensive, and easier to care for the procedure that deserves to be used more frequently.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Chemistry, Multidisciplinary

Semiconductor SERS on Colourful Substrates with Fabry-Perot Cavities

Feifan Li, Xinyang Mu, Xueqing Tang, Ge Song, Hongzhao Sun, Xiuling Zha, Peiyan Sun, Jianhui Fang, Dongmei Hu, Shan Cong, Zhigang Zhao

Summary: Non-metallic materials have unique advantages over metal materials as active substrates for surface-enhanced Raman scattering (SERS). However, the Raman enhancement achieved with non-metallic materials is considerably lower due to their inefficient interaction with the incident wavelength. In this study, colourful semiconductor-based SERS substrates are proposed for the first time by utilizing a Fabry-Perot cavity, which allows for manipulating light. By finely adjusting the absorption frequency and intensity, resonant absorption can be achieved with various non-metal SERS substrates, leading to a sensitivity enhancement of approximately 100 times.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2023)

Article Energy & Fuels

Modelling and performance evaluation of a novel passive thermoelectric system based on radiative cooling and solar heating for 24-hour power-generation

Cun-Hai Wang, Hao Chen, Ze-Yi Jiang, Xin-Xin Zhang, Fu-Qiang Wang

Summary: In this paper, a passive thermoelectric system that produces continuous electric power during a full 24-hour day is proposed. The system utilizes radiative cooling and solar heating to maintain and amplify the thermoelectric output. The effects of various factors on system performance are studied, and the system's seasonal and locational performance in China is evaluated.

APPLIED ENERGY (2023)

Article Andrology

Epididymis cell atlas in a patient with a sex development disorder and a novel NR5A1 gene mutation

Jian-Wu Shi, Yi-Wen Zhou, Yu-Fei Chen, Mei Ye, Feng Qiao, Jia-Wei Tian, Meng-Ya Zhang, Hao-Cheng Lin, Gang-Cai Xie, Kin Lam Fok, Hui Jiang, Yang Liu, Hao Chen

Summary: This study characterized the cell atlas of the epididymis in a 46,XY disorders of sex development patient with a novel heterozygous mutation in the NR5A1 gene. The patient exhibited feminization of external genitalia and dysplastic testis. Single-cell RNA sequencing analysis revealed an increase in fibroblast cells and a decrease in main epididymal epithelial cells, suggesting an association with the epithelial-to-mesenchymal transition process. This study provides important insights into the pathophysiology of DSD.

ASIAN JOURNAL OF ANDROLOGY (2023)

Article Thermodynamics

Study and application of the shift-temperature of heating fluid for zeotropic mixtures in Rankine

Shujuan Bu, Xinle Yang, Weikang Li, Chang Su, Xin Wang, Xunan Liu, Ning Yu, Guanyu Wang, Jupeng Tang

Summary: Theoretical formulations for the shift-temperature of zeotropic mixtures (Tshift) were derived in different pinch point scenarios. Tshift was corrected and calculated using the impact factor analysis and Dragonfly algorithm. The optimal zeotropic mixture was matched based on Tg, in and Tshift. The results showed that Tshift is a property of every zeotropic mixture and is influenced by critical temperature and evaporation/condensation temperatures.

INTERNATIONAL COMMUNICATIONS IN HEAT AND MASS TRANSFER (2023)

Article Obstetrics & Gynecology

Walking or jogging during pregnancy increases the success rate of vaginal birth after cesarean delivery: A multicenter, retrospective cohort study

Jiaming Rao, Dazhi Fan, Demei Lu, Yan Liu, Zhaoxia Wu, Jieyun He, Xinjuan Liu, BingJie Peng, Xiaoling Guo, Zhengping Liu

Summary: This study aimed to investigate the association between walking or jogging during pregnancy and the success rate of vaginal birth after cesarean delivery (VBAC). The results showed that women who walked or jogged for >= 200 min/week during pregnancy had a higher likelihood of successful VBAC in women who underwent a trial of labor after cesarean delivery.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2023)

Article Pharmacology & Pharmacy

Corosolic acid-modified lipid nanoparticles as delivery carriers for DNA vaccines against avian influenza

Ziyan Guo, Qiufang Jing, Zhongyu Xu, Dahe Zhang, Wenyun Zheng, Fuzheng Ren

Summary: Cholesterol (CHOL) is important for lipid nanoparticles (LNPs) used in gene delivery. This study developed corosolic acid (CA)-modified lipid nanoparticles (CLNPs) by replacing CHOL in LNPs to deliver pDNA. CLNPs with a higher CHOL/CA ratio showed similar characteristics to LNPs, but exhibited increased cellular uptake and enhanced transfection efficacy with low cytotoxicity. In vivo experiments on chickens showed that CLNPs with a N/P ratio of 3 could induce similar immune responses as LNPs with a higher N/P ratio, suggesting the potential use of CLNPs in DNA vaccines against avian influenza.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2023)

Article Endocrinology & Metabolism

Insulin-Like Growth Factor 1 and Risk of Cardiovascular Disease: Results From the UK Biobank Cohort Study

Jiayang Lin, Linjie Yang, Junlin Huang, Yating Liu, Xuzhen Lei, Ruxin Chen, Bingyan Xu, Chensihan Huang, Weijuan Dou, Xueyun Wei, Deying Liu, Peizhen Zhang, Yan Huang, Zhimin Ma, Huijie Zhang

Summary: This study found that both low and high levels of circulating IGF-1 are associated with increased risk of cardiovascular disease in the general population. The results highlight the importance of monitoring IGF-1 status on cardiovascular health.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2023)

Article Chemistry, Analytical

An efficient method for qualitation and quantitation of multi-components of the herbal medicine Qingjin Yiqi Granules

Xiaohua Yang, Shuangqi Wang, Lina Qi, Shujing Chen, Kunze Du, Ye Shang, Jiading Guo, Shiming Fang, Jin Li, Han Zhang, Yanxu Chang

Summary: The quality evaluation of Qingjin Yiqi Granules (QJYQ), a Traditional Chinese Medicines (TCMs) prescription for postCOVID-19 condition, was conducted using deep-learning assisted mass defect filter (deep-learning MDF) for qualitative analysis and ultra-high performance liquid chromatography and scheduled multiple reaction monitoring method (UHPLC-sMRM) for precise quantitation. The study successfully classified and identified the phytochemical components of QJYQ and quantified 50 components. The comprehensive evaluation strategy established in this study provides an effective tool for accurately evaluating the quality of QJYQ as a whole.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2023)

Meeting Abstract Immunology

Obesity Challenge Drives Distinct Maternal Immune Response Changes in Normal Pregnant and Abortion Prone Mouse Models

Yanhong Li, Jiajia Chen, Yifei Sang, Yikong Lin, Lin Xu, Dajin Li, Meirong Du

JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2023)

Article Materials Science, Multidisciplinary

Ambient-stable polyethyleneimine functionalized Ti3C2TX nanohybrid corrosion inhibitor for copper in alkaline electrolyte

Yuxin Liu, Baomin Fan, Bin Xu, Biao Yang

Summary: In this study, it was found that decorating polyethyleneimine (PEI) on Ti3C2TX could solve its oxidation problem in aqueous solutions. The functionalized Ti3C2TX with PEI exhibited excellent corrosion inhibition for copper in 0.5 M NaOH solution. The Ti-N bond formed by Coulomb attraction was responsible for the grafting of PEI. The anchored polymer chain effectively capped the oxidation-sensitive defects on Ti3C2TX, leading to improved colloidal stability. When the mass ratio of PEI/Ti3C2TX reached 0.33 (M@0.33P), the aqueous dispersion showed robust shelf-life for 30 days at 25 degrees C. M@nP acted as a mixed-type inhibitor with dominant anodic effect for copper in NaOH solutions, and M@0.33P was the optimal prototype that further mitigated copper dissolution. The protective mechanism of M@nP for copper in alkaline electrolyte involved reduction of interfacial cupric/cuprous species by Ti3C2TX, electrostatic adsorption, and electrons sharing of PEI.

MATERIALS LETTERS (2023)

Article Chemistry, Multidisciplinary

Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability

Suet Yen Chong, Xiaoyuan Wang, Louis van Bloois, Chenyuan Huang, Nilofer Sayed Syeda, Sitong Zhang, Hui Jun Ting, Vaarsha Nair, Yuanzhe Lin, Charles Kang Liang Lou, Ayca Altay Benetti, Xiaodong Yu, Nicole Jia Ying Lim, Michelle Siying Tan, Hwee Ying Lim, Sheau Yng Lim, Chung Hwee Thiam, Wen Donq Looi, Olga Zharkovaa, Nicholas W. S. Chew, Cheng Han Ngg, Glenn Kunnath Bonney, Mark Muthiah, Xiaoyuan Chen, Giorgia Pastorin, A. Mark Richards, Veronique Angeli, Gert Storm, Jiong-Wei Wang

Summary: Atherosclerosis is a chronic vascular disease characterized by plaque formation in artery walls, and docosahexaenoic acid (DHA) has been suggested as a therapeutic option due to its anti-inflammatory and antioxidant properties. However, inconsistent results in clinical trials may be due to variations in DHA formulation and bioavailability. In this study, an injectable liposomal DHA formulation was developed, which protected DHA against degradation and increased its concentration within plaques. This formulation showed promising results in attenuating atherosclerosis progression and stabilizing plaques in experimental models.

JOURNAL OF CONTROLLED RELEASE (2023)

Article Materials Science, Multidisciplinary

Non-ultrawide bandgap CsPbBr 3 nanosheet for sensitive deep ultraviolet photodetection

Chun-Yan Wu, Yu-Xuan Le, Li-Yan Liang, Jing-Yue Li, Feng-Xia Liang, Shi-Rong Chen, Xiao-Ping Yang, Yu-Xue Zhou, Lin-Bao Luo

Summary: In this study, a sensitive deep ultraviolet (DUV) photodetector was fabricated using CsPbBr3 nanosheets synthesized through confined-space growth at room temperature. The photodetector exhibited a blueshift in peak photoresponse with decreasing thickness, and a 68 nm CsPbBr3 nanosheet based device displayed a peak response to 265 nm illumination. Theoretical simulation revealed that the blueshift was related to the wavelength-dependent absorption coefficient of CsPbBr3 nanosheets.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2023)

Article Chemistry, Organic

Atroposelective Access to Dihydropyridinones with C-N Axial and Point Chirality via NHC-Catalyzed [3+3] Annulation

Yanting Li, Xiao-Yong Duan, Chengxian Yang, Yamei Wei, Jiahan Li, Xiaojie Ren, Jing Qi

Summary: This article describes a N-heterocyclic carbene-catalyzed atroposelective [3+3] annulation of enals with 2-aminomaleate derivatives. A series of substituted dihydropyridones with both C-N axis and point chirality were synthesized with good diastereo- and enantioselectivity under mild conditions. This efficient strategy introduces an additional point chiral element to an axial backbone, and the resulting structurally interesting atropisomers may have potential applications in drug discovery.

JOURNAL OF ORGANIC CHEMISTRY (2023)

Article Materials Science, Ceramics

Kinetic mechanism of anisotropic sintering shrinkage in triaxial porcelain

Hui Yang, Yucheng Chang, Yumei Wang, Lijuan Wang, Xi Zhang, Jinsheng Liang

Summary: By using mathematical deconvolution analysis, the kinetic mechanisms of sintering shrinkage at different temperatures were separated into the formation of Al-Si-spinel, nucleation of mullite, and growth of mullite. The anisotropy of sintering shrinkage is primarily attributed to the parallel arrangement of clay plates, and the dominant role of mullite growth during densification.

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY (2023)

Article Chemistry, Analytical

A novel photoelectrochemical sensor based on three-dimensional rGO@Au-sensitized cauliflower-like CdS heterojunction for the effective and sensitive detection of copper (II) in pool water

Jiaodi Li, Linzi Huang, Minghui Huang, Yaqi Yang, Zhifang Liu, Chenxi Wang, Yixi Xie, Pengcheng Zhao, Junjie Fei

Summary: In this study, a three-dimensional CdS/rGO@Au heterojunction was successfully synthesized and used for selective photoelectrochemical detection of Cu2+. The CdS/rGO@Au heterojunction showed a photocurrent 7 times higher than that of CdS, indicating a good photoresponse intensity. The developed photoelectrochemical sensor was able to detect Cu2+ concentration in the range of 5 nM to 4 mu M with a low limit of detection of 2.88 nM.

MICROCHEMICAL JOURNAL (2023)

No Data Available