Journal
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
Volume 26, Issue 10, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0960-1317/26/10/107001
Keywords
CO2-laser; thermal bonding; PMMA; orthogonal experiment
Categories
Funding
- National Natural Science Foundation of China [51405214]
- Liaoning Province Doctor Start up Fund [20141131]
- Fund of Liaoning Province Education Administration [L2014241]
- Fund in Liaoning University of Technology [X201301]
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A smart design method to transform the original two-layer microfluidic chip into a four-layer 3D microfluidic chip is proposed. A novel fabrication method is established to rapidly and effectively produce a four-layer microfluidic chip device made entirely from polymethylmethacrylate (PMMA). Firstly, the CO2-laser cuts the PMMA sheets by melting and blowing away vaporized material from the parent material to obtain high-quality channels of the microfluidic chip. An orthogonal experimental method is used to study its processing stability. In addition, a simple, rapid thermal bonding technique is successfully applied in fabricating the four-layer microfluidic chip, which has a bond strength of 1.3 MPa. A wooden pole is used to improve the accuracy of the alignment. Finally, a mixing experiment with blue ink and water is carried out, which proves that this smart design method and rapid manufacturing technology are successful.
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