Journal
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
Volume 26, Issue 2, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0960-1317/26/2/023002
Keywords
bone; biosensor; osteoporosis
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Bone is an active organ with the capacity of continuous remodeling throughout adult life. In view of the fact that the current gold standard to assess bone remodeling, bone mineral density, suffers from certain limitations, newer techniques are being developed. Currently enzyme-linked immunosorbent assay is commonly used to assess bone turnover markers; the technique, however, is expensive, time consuming and needs trained personnel. Thus, there is a growing demand to fabricate different types of biosensors to provide low cost miniaturized platforms to assess the bone remodeling process more accurately. This review focuses on the latest advancements in the field of bone biosensing technologies. Its results might help provide possible solutions for translation of this technology for point-of-care diagnostic applications.
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