Inhibition of clinical pathogenic herpes simplex virus 1 strains with enzymatically created siRNA pools

Preclinical and clinical development of siRNA-based therapeutics

(2015) Gulnihal Ozcan et al.   ADVANCED DRUG DELIVERY REVIEWS

Carriage of herpes simplex virus and human papillomavirus in oral mucosa is rare in young women: A long-term prospective follow-up

(2015) Johanna Mäki et al.   JOURNAL OF CLINICAL VIROLOGY

An investigation of herpes simplex virus type 1 latency in a novel mouse dorsal root ganglion model suggests a role for ICP34.5 in reactivation

(2015) R. K. Mattila et al.   JOURNAL OF GENERAL VIROLOGY

Combination siRNA therapy against feline coronavirus can delay the emergence of antiviral resistance in vitro

(2015) Phillip McDonagh et al.   VETERINARY MICROBIOLOGY

Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis

(2015) Edward Sionov et al.   PLoS Pathogens

Prevention of Herpes Simplex Virus Induced Stromal Keratitis by a Glycoprotein B-Specific Monoclonal Antibody

(2015) Adalbert Krawczyk et al.   PLoS One

Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex Virus 1 Infection Model

(2014) Subhajit Biswas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Resistance of herpes simplex viruses to acyclovir: An update from a ten-year survey in France

(2014) Emilie Frobert et al.   ANTIVIRAL RESEARCH

RNA interference inhibits herpes simplex virus type 1 isolated from saliva samples and mucocutaneous lesions

(2014) Amanda Perse da Silva et al.   Brazilian Journal of Infectious Diseases

Innate responses to small interfering RNA pools inhibiting herpes simplex virus infection in astrocytoid and epithelial cells

(2014) Henrik Paavilainen et al.   Innate Immunity

Herpes simplex virus type 1 genital herpes in young women: current trend in Northern Finland

(2014) Hanna Tuokko et al.   SEXUALLY TRANSMITTED INFECTIONS

Acyclovir Prophylaxis Predisposes to Antiviral-Resistant Recurrent Herpetic Keratitis

(2013) Monique van Velzen et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of adenovirus multiplication by short interfering RNAs directly or indirectly targeting the viral DNA replication machinery

(2012) Doris Kneidinger et al.   ANTIVIRAL RESEARCH

High-throughput purification of double-stranded RNA molecules using convective interaction media monolithic anion exchange columns

(2012) Alesia Romanovskaya et al.   JOURNAL OF CHROMATOGRAPHY A

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

(2012) Line S. Reinert et al.   JOURNAL OF CLINICAL INVESTIGATION

Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials

(2012) Christine Johnston et al.   LANCET

HIV Develops Indirect Cross-resistance to Combinatorial RNAi Targeting Two Distinct and Spatially Distant Sites

(2012) Priya S Shah et al.   MOLECULAR THERAPY

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enzymatically Produced Pools of Canonical and Dicer-Substrate siRNA Molecules Display Comparable Gene Silencing and Antiviral Activities against Herpes Simplex Virus

(2012) Alesia Romanovskaya et al.   PLoS One

Treatment of experimental autoimmune encephalomyelitis in SJL/J mice with a replicative HSV-1 vector expressing interleukin-5

(2011) M Nygårdas et al.   GENE THERAPY

Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells

(2011) Stéphanie Grosse et al.   MOLECULAR THERAPY

Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor

(2010) S. Sukla et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Internalization of Coxsackievirus A9 Is Mediated by  2-Microglobulin, Dynamin, and Arf6 but Not by Caveolin-1 or Clathrin

(2010) O. Heikkila et al.   JOURNAL OF VIROLOGY

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

(2010) J. DeVincenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of coxsackievirus B3 and related enteroviruses by antiviral short interfering RNA pools produced using  6 RNA-dependent RNA polymerase

(2009) M. Nygardas et al.   JOURNAL OF GENERAL VIROLOGY

Acyclovir Susceptibility and Genetic Characteristics of Sequential Herpes Simplex Virus Type 1 Corneal Isolates from Patients with Recurrent Herpetic Keratitis

(2009) Rui Duan et al.   JOURNAL OF INFECTIOUS DISEASES

Herpes Simplex Virus Type 1 Us3 Gene Deletion Influences Toll-like Receptor Responses in Cultured Monocytic Cells

(2008) Piritta Peri et al.   Virology Journal