Differential association of STAT3 and HK-II expression in hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma

Association of Single Nucleotide Polymorphism rs1053004 in Signal Transducer and Activator of Transcription 3 (STAT3) with Susceptibility to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B

(2015) Nawin Chanthra et al.   Asian Pacific Journal of Cancer Prevention

Differences in antiproliferative effect of STAT3 inhibition in HCC cells with versus without HBV expression

(2015) Yun Hong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer

(2015) Weijie Guo et al.   HEPATOLOGY

Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

(2015) Tung-Hung Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatocellular carcinoma in a large medical center of China over a 10-year period: evolving therapeutic option and improving survival

(2015) Qianqian Zhu et al.   Oncotarget

Attributable Causes of Liver Cancer Mortality and Incidence in China

(2014) Jin-Hu Fan et al.   Asian Pacific Journal of Cancer Prevention

Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR-STAT3/microRNA143 pathway

(2014) Zhengkun Li et al.   CANCER SCIENCE

Evidence for Heightened Hexokinase II Immunoexpression in Hepatocyte Dysplasia and Hepatocellular Carcinoma

(2014) Grace Guzman et al.   DIGESTIVE DISEASES AND SCIENCES

Activity of Hexokinase Is Increased by Its Interaction with Hepatitis C Virus Protein NS5A

(2014) C. Ramiere et al.   JOURNAL OF VIROLOGY

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

(2013) Krushna C. Patra et al.   CANCER CELL

Interaction of signal transducer and activator of transcription 3 polymorphisms with hepatitis B virus mutations in hepatocellular carcinoma

(2013) Jiaxin Xie et al.   HEPATOLOGY

Signal transducer and activator of transcription 3 is a proviral host factor for hepatitis C virus

(2013) Erin M. McCartney et al.   HEPATOLOGY

Glycolysis Back in the Limelight: Systemic Targeting of HK2 Blocks Tumor Growth

(2013) S. Ros et al.   Cancer Discovery

Oncogenic Viruses and Tumor Glucose Metabolism: Like Kids in a Candy Store

(2012) E. Noch et al.   MOLECULAR CANCER THERAPEUTICS

Choline Kinase Alpha and Hexokinase-2 Protein Expression in Hepatocellular Carcinoma: Association with Survival

(2012) Sandi A. Kwee et al.   PLoS One

Extracellular Hepatitis C Virus Core Protein Activates STAT3 in Human Monocytes/Macrophages/Dendritic Cells via an IL-6 Autocrine Pathway

(2011) Robert S. Tacke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma

(2011) Wei-Tien Tai et al.   JOURNAL OF HEPATOLOGY

Reduced survival of patients with hepatocellular carcinoma expressing hexokinase II

(2011) Lei Gong et al.   MEDICAL ONCOLOGY

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide-dependent impairment of oxidative DNA repair

(2010) Keigo Machida et al.   HEPATOLOGY

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3

(2010) Yu Wang et al.   JOURNAL OF HEPATOLOGY

Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy

(2008) Saroj P. Mathupala et al.   SEMINARS IN CANCER BIOLOGY