A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection

Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults

(2022) Said Abdallah Jongo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa

(2022) Joana C. Silva et al.   Nature Communications

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial

(2021) Mehreen S Datoo et al.   LANCET

Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial

(2021) Zita Sulyok et al.   Nature Communications

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity

(2021) Agnes Mwakingwe-Omari et al.   NATURE

Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial

(2021) Martina Oneko et al.   NATURE MEDICINE

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection

(2021) Sean C. Murphy et al.   PLoS Pathogens

Safety and efficacy of a three-dose regimen of Plasmodium falciparum sporozoite vaccine in adults during an intense malaria transmission season in Mali: a randomised, controlled phase 1 trial

(2021) Mahamadou S Sissoko et al.   LANCET INFECTIOUS DISEASES

A systematic review of factors affecting adherence to malaria chemoprophylaxis amongst travellers from non-endemic countries

(2020) Julian Ahluwalia et al.   MALARIA JOURNAL

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential

(2020) Kara A. Moser et al.   Genome Medicine

Multidose Priming and Delayed Boosting Improve PfSPZ Vaccine Efficacy against Heterologous P. falciparum Controlled Human Malaria Infection

(2020) Kirsten E Lyke et al.   CLINICAL INFECTIOUS DISEASES

Safety and Differential Antibody and T-Cell Responses to Plasmodium falciparum Sporozoite Vaccine by Age in Tanzanian Adults, Adolescents, Children, and Infants

(2019) Said A. Jongo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Serologic Markers of Previous Malaria Exposure and Functional Antibodies Inhibiting Parasite Growth Are Associated With Parasite Kinetics Following a Plasmodium falciparum Controlled Human Infection

(2019) Jane Achan et al.   CLINICAL INFECTIOUS DISEASES

Safety, tolerability, and immunogenicity of PfSPZ Vaccine administered by direct venous inoculation to infants and young children: findings from an age de-escalation, dose-escalation double-blinded randomized, controlled study in western Kenya

(2019) Laura C Steinhardt et al.   CLINICAL INFECTIOUS DISEASES

Dose-Dependent Infectivity of Aseptic, Purified, Cryopreserved Plasmodium falciparum 7G8 Sporozoites in Malaria-Naive Adults

(2019) Matthew B Laurens et al.   JOURNAL OF INFECTIOUS DISEASES

Increase of dose associated with decrease in protection against controlled human malaria infection by PfSPZ Vaccine in Tanzanian adults

(2019) Said A Jongo et al.   CLINICAL INFECTIOUS DISEASES

Ivermectin for causal malaria prophylaxis: a randomised controlled human infection trial

(2019) Wolfram G. Metzger et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoites Vaccine in Tanzanian Adults

(2018) Said A. Jongo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

(2018) Bertrand Lell et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men

(2018) Ally Olotu et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

The geography of imported malaria to non-endemic countries: a meta-analysis of nationally reported statistics

(2017) Andrew J Tatem et al.   LANCET INFECTIOUS DISEASES

Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial

(2017) Mahamadou S Sissoko et al.   LANCET INFECTIOUS DISEASES

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

(2017) Mihály Sulyok et al.   LANCET INFECTIOUS DISEASES

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

(2017) Benjamin Mordmüller et al.   NATURE

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

(2017) Kirsten E. Lyke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

(2016) Andrew S Ishizuka et al.   NATURE MEDICINE

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

(2015) Gloria P Gómez-Pérez et al.   MALARIA JOURNAL

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

(2015) Benjamin Mordmüller et al.   MALARIA JOURNAL

The march toward malaria vaccines

(2015) Stephen L. Hoffman et al.   VACCINE

Limit of blank and limit of detection of Plasmodium falciparum thick blood smear microscopy in a routine setting in Central Africa

(2014) Fanny Joanny et al.   MALARIA JOURNAL

Temporal Dynamics of the Primary Human T Cell Response to Yellow Fever Virus 17D As It Matures from an Effector- to a Memory-Type Response

(2013) K. Blom et al.   JOURNAL OF IMMUNOLOGY

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

(2013) R. A. Seder et al.   SCIENCE

Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites

(2012) Meta Roestenberg et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity

(2011) J. E. Epstein et al.   SCIENCE

Development of a metabolically active, non-replicating sporozoite vaccine to preventPlasmodium falciparummalaria

(2010) Stephen L. Hoffman et al.   Human vaccines & immunotherapeutics