4.6 Review

Current cancer burden in China: epidemiology, etiology, and prevention

Journal

CANCER BIOLOGY & MEDICINE
Volume 19, Issue 8, Pages 1121-1138

Publisher

CHINA ANTI-CANCER ASSOC
DOI: 10.20892/j.issn.2095-3941.2022.0231

Keywords

Cancer burden; risk factor; prevention; China

Funding

  1. Sanming Project of Medicine in Shenzhen [SZSM201911015]

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Cancer has become the leading cause of death in China, with significant changes in cancer epidemiology. Lung, colorectal, and gastric cancers are the most common types, while lung, liver, and stomach cancers are the deadliest. The 5-year survival rate for cancer has significantly improved in recent decades. Modifiable risk factors for cancer development include infectious agents, smoking, alcohol consumption, obesity, unhealthful dietary habits, and inadequate physical activity. The Chinese government has made efforts to reduce the cancer burden.
Cancer has become the most common cause of death in China. Owing to rapid economic development, improved livelihood, and shifts in risk factors, cancer epidemiology has experienced substantial changes during the past several decades. In this review, we aim to describe the current cancer epidemiology of the main types of cancer in China, report major risk factors associated with cancer development, and summarize the contributions of the Chinese government to controlling the cancer burden. A total of 4,064,000 new cases were diagnosed in China in 2016. The most frequent types are lung cancer (828,100; 20.4%), colorectal cancer (408,000; 10.0%), and gastric cancer (396,500; 9.8%). Lung (657,000; 27.2%), liver (336,400, 13.9%), and stomach (288,500; 12.0%) cancers are the 3 most deadly cancers in the general population. The 5-year survival rate for cancer has dramatically increased in recent decades. However, liver and particularly pancreatic cancers still have the poorest prognosis. The main modifiable risk factors associated with cancer development include infectious agents, smoking, alcohol consumption, obesity, unhealthful dietary habits, and inadequate physical activity. The Chinese government has made unremitting efforts to decrease the cancer burden, including cancer education and investment in cancer screening programs.

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