Intraocular RGD-Engineered Exosomes and Active Targeting of Choroidal Neovascularization (CNV)

Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development

(2022) Gopa Kumar Gopinadhan Nair et al.   Journal of Clinical Medicine

Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

(2021) Dongli Li et al.   Stem Cell Research & Therapy

Unlocking the Power of Exosomes for Crossing Biological Barriers in Drug Delivery

(2021) Rebekah Omarkhail Elliott et al.   Pharmaceutics

Uptake and Distribution of Administered Bone Marrow Mesenchymal Stem Cell Extracellular Vesicles in Retina

(2021) Biji Mathew et al.   Cells

RGD-modified multifunctional nanoparticles encapsulating salvianolic acid A for targeted treatment of choroidal neovascularization

(2021) Junxiu Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

PREVALENCE AND RISK FACTORS FOR THE DEVELOPMENT OF PHYSICIAN-GRADED SUBRETINAL FIBROSIS IN EYES TREATED FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

(2020) Kelvin Yi Chong Teo et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities

(2020) Priyatham S. Mettu et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

(2019) Huixin Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues

(2019) Sherif E. Emam et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations

(2018) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model

(2017) Laurence A. Hutton-Smith et al.   MOLECULAR PHARMACEUTICS

Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment

(2017) Xiaohui Zhang et al.   MOLECULAR THERAPY

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

(2017) Hironori Uehara et al.   Translational Vision Science & Technology

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

(2016) Haojun Chen et al.   Theranostics

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

RGD-conjugated silica-coated gold nanorods on the surface of carbon nanotubes for targeted photoacoustic imaging of gastric cancer

(2014) Can Wang et al.   Nanoscale Research Letters

RGD-conjugated solid lipid nanoparticles inhibit adhesion and invasion of αvβ3 integrin-overexpressing breast cancer cells

(2014) Dan Shan et al.   Drug Delivery and Translational Research

Exosomes from Retinal Astrocytes Contain Antiangiogenic Components That Inhibit Laser-induced Choroidal Neovascularization

(2013) Amir Reza Hajrasouliha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration

(2012) Jeffrey S. Heier et al.   OPHTHALMOLOGY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV

(2009) S R Singh et al.   GENE THERAPY

Cilengitide: an integrin-targeting arginine–glycine–aspartic acid peptide with promising activity for glioblastoma multiforme

(2008) David A Reardon et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS