Article
Multidisciplinary Sciences
Shinji Kasai, Kentaro Itokawa, Nozomi Uemura, Aki Takaoka, Shogo Furutani, Yoshihide Maekawa, Daisuke Kobayashi, Nozomi Imanishi-Kobayashi, Michael Amoa-Bosompem, Katsunori Murota, Yukiko Higa, Hitoshi Kawada, Noboru Minakawa, Tran Chi Cuong, Nguyen Thi Yen, Tran Vu Phong, Sath Keo, Kroesna Kang, Kozue Miura, Lee Ching Ng, Hwa-Jen Teng, Samuel Dadzie, Sri Subekti, Kris Cahyo Mulyatno, Kyoko Sawabe, Takashi Tomita, Osamu Komagata
Summary: Aedes aegypti, the main mosquito vector for dengue and other arboviral infectious diseases, has developed high levels of pyrethroid resistance in populations collected from Vietnam and Cambodia. This resistance could pose a serious threat to the control of dengue fever and other Aedes-borne infectious diseases.
Article
Multidisciplinary Sciences
Talya Shragai, Juliana Perez-Perez, Marcela del Pilar Quimbayo-Forero, Raul Rojo, Laura C. Harrington, Guillermo Rua-Uribe
Summary: Dengue is becoming an increasing global threat in rapidly growing urban areas. This study analyzes nine years of dengue case data in Medellin, Colombia and finds that changes in accessibility and usage of public transit are correlated with changes in the spread and magnitude of localized outbreaks. Locations closer to and with greater utilization of public transit have higher dengue incidence, with a stronger effect observed in lower socioeconomic status areas. These results emphasize the importance of public health services in conjunction with urban growth.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Cory W. Morin, Samuel Sellers, Kristie L. Ebi
Summary: This study explored the relationship between seasonal climate variability and dengue fever (DF) in Brazil using temperature-based models. The results showed that areas with higher mosquito survival probabilities and shorter extrinsic incubation periods (EIPs) were more likely to have DF case reports, but with significant intra-annual variability. The study also extrapolated the findings to the Americas, mapping the seasonal change in the range of areas suitable for dengue virus transmission and the population living in those areas using climate data from the past decade (2010-2019).
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Public, Environmental & Occupational Health
Kyle R. Ryff, Aidsa Rivera, Dania M. Rodriguez, Gilberto A. Santiago, Freddy A. Medina, Esther M. Ellis, Jomil Torres, Ann Pobutsky, Jorge Munoz-Jordan, Gabriela Paz-Bailey, Laura E. Adams
Summary: From 2010 to 2020, approximately 30,000 cases of dengue were reported in the US territories, with the highest incidence during outbreak years. Children and adolescents aged <20 years were disproportionately affected, highlighting the need for interventions tailored for this population. Ongoing education for healthcare providers and dengue case surveillance and serotyping are important for improving patient outcomes and guiding future control measures.
MMWR SURVEILLANCE SUMMARIES
(2023)
Review
Immunology
Zhuanzhuan Liu, Qingxin Zhang, Liya Li, Junjie He, Jinyang Guo, Zichen Wang, Yige Huang, Zimeng Xi, Fei Yuan, Yiji Li, Tingting Li
Summary: This review explores the correlations between temperature and dengue epidemics, including the distribution and development of Aedes mosquitoes, the structure of DENV, and the vector competence of Aedes mosquitoes. Additionally, it discusses the immune and metabolic mechanism through which temperature affects the vector competence of Aedes mosquitoes to transmit DENV.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
L. L. Lima, A. P. F. Atman
Summary: In an increasingly interconnected society, preventing epidemics has become a major challenge. Using an agent-based model, the authors investigated the network morphology of a dengue endemic region considering different serotypes and a small population. The simulation results indicate that the spread of dengue is primarily driven by human-to-human and human-to-mosquito interaction, reinforcing the importance of controlling the vector to prevent episodes of epidemic outbreaks.
Article
Entomology
Maria E. Santana-Roman, Paola Maycotte, Salvador Uribe-Carvajal, Cristina Uribe-Alvarez, Nayeli Alvarado-Medina, Mohsin Khan, Aleem Siddiqui, Victoria Pando-Robles
Summary: Dengue is a growing public health concern without specific treatment, and vector control remains crucial for prevention. Studies show that DENV infection alters mitochondrial physiology in mosquito cells, affecting redox metabolism and membrane potential. The maintenance of mitochondrial function through fusion may play a vital role in the DENV-infected cells.
Article
Medicine, General & Internal
Triwibowo Ambar Garjito, Lulus Susanti, Mujiyono Mujiyono, Mega Tyas Prihatin, Dwi Susilo, Sidiq Setyo Nugroho, Mujiyanto Mujiyanto, Raden Ajeng Wigati, Tri Baskoro Tunggul Satoto, Sylvie Manguin, Laurent Gavotte, Roger Frutos
Summary: There are various methods to collect and assess the abundance of dengue vector mosquitoes, but the lack of long-term sampling methods may result in variability and lack of statistical significance in the results. There is no correlation between the collection methods and the presence of dengue virus in mosquitoes or the incidence of dengue, and the efficacy of a given method is inconsistent across different locations.
FRONTIERS IN MEDICINE
(2021)
Article
Immunology
Jessica E. Manning, Sophana Chea, Daniel M. Parker, Jennifer A. Bohl, Sreyngim Lay, Allyson Mateja, Somnang Man, Sreynik Nhek, Aiyana Ponce, Sokunthea Sreng, Dara Kong, Soun Kimsan, Claudio Meneses, Michael P. Fay, Seila Suon, Rekol Huy, Chanthap Lon, Rithea Leang, Fabiano Oliveira
Summary: Results from a longitudinal pediatric cohort in Cambodia indicate that children with high levels of antibodies to Aedes aegypti mosquito saliva are more likely to contract dengue fever, but are less likely to show clinical symptoms.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Audrey Lenhart, Carmen Elena Castillo, Elci Villegas, Neal Alexander, Veerle Vanlerberghe, Patrick van der Stuyft, Philip S. McCall
Summary: A large-scale trial in Venezuela found that the use of insecticide treated curtains and water jar covers can effectively control dengue vector populations, especially when used in combination.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Entomology
Eunice Nayeli Martinez-Garcia, Esteban E. Diaz-Gonzalez, Carlos F. Marina, J. Guillermo Bond, Jorge J. Rodriguez-Rojas, Gustavo Ponce-Garcia, Rosa M. Sanchez-Casas, Ildefonso Fernandez-Salas
Summary: Diseases transmitted by Aedes mosquitoes are a growing global concern. The Sterile Insect Technique (SIT) is a strategy for controlling mosquito populations, and egg storage is essential in SIT programs. This study found that two moisturizing substances, hydrolyzed collagen and Hyalurosmooth(R), can prolong the viability of Aedes mosquito eggs, showing promise in mass rearing insect production for vector control.
Article
Chemistry, Medicinal
Chao Yang, Wansheng Xie, Heqian Zhang, Wenjian Xie, Tiantian Tian, Zhiwei Qin
Summary: Dengue is an acute tropical infectious disease transmitted by mosquitoes, posing a major challenge to global public health. The lack of clinically proven specific drugs for prevention and treatment is mainly due to the incomplete understanding of the pathogenesis of dengue fever.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Environmental Sciences
Maria S. Lopez, Andre A. Gomez, Gabriela V. Müller, Elisabet Walker, Michael A. Robert, Elizabet L. Estallo
Summary: This study analyzed the relationship between climate change and dengue fever, and found that there is a correlation between increasing temperatures and the rise in dengue cases as well as its geographical expansion. This suggests that climate change is an important driver of the continuous spread of dengue fever in Argentina.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Parasitology
Maria C. Carrasquilla, Mario I. Ortiz, Cielo Leon, Silvia Rondon, Manisha A. Kulkarni, Benoit Talbot, Beate Sander, Heriberto Vasquez, Juan M. Cordovez, Camila Gonzalez
Summary: A study conducted in Ibague, Colombia found that Aedes aegypti and Aedes albopictus mosquitoes are vectors for dengue, Zika, and chikungunya viruses, with dengue and chikungunya circulating in the area but Zika virus remaining undetected. The research results showed that mosquitoes were mainly found in low socioeconomic areas and indoors, with a higher number of female mosquitoes that have fed on human blood, indicating a high risk of arbovirus transmission in Ibague.
PARASITES & VECTORS
(2021)
Article
Virology
Kacey C. Ernst, Kathleen R. Walker, A. Lucia Castro-Luque, Chris Schmidt, Teresa K. Joy, Maureen Brophy, Pablo Reyes-Castro, Rolando Enrique Diaz-Caravantes, Veronica Ortiz Encinas, Alfonso Aguilera, Mercedes Gameros, Rosa Elena Cuevas Ruiz, Mary H. Hayden, Gerardo Alvarez, Andrew Monaghan, Daniel Williamson, Josh Arnbrister, Eileen Jeffrey Gutierrez, Yves Carriere, Michael A. Riehle
Summary: Dengue transmission is influenced by various factors such as environment, Aedes aegypti mosquitoes, dengue viruses, and humans. Mosquito sampling was conducted in multiple urban areas in the Arizona-Sonora desert region to study the factors affecting disease transmission. The abundance of potential vectors, mosquito age, and site-specific temperature were analyzed to estimate disease transmission. Results showed differences in vector abundance between endemic and non-endemic regions, with Tucson, Arizona having a higher estimated abundance than dengue endemic regions in Mexico.
Article
Environmental Sciences
Guillaume Rohat, Andrew Monaghan, Mary H. Hayden, Sadie J. Ryan, Elodie Charriere, Olga Wilhelmi
ENVIRONMENTAL RESEARCH LETTERS
(2020)
Article
Public, Environmental & Occupational Health
Pablo A. Reyes-Castro, Kacey C. Ernst, Kathleen R. Walker, Mary H. Hayden, Gerardo Alvarez-Hernandez
Summary: The study found that many respondents had heard of RMSF but still lacked knowledge and prevention strategies, especially in low socioeconomic areas. Those in low-income groups were less likely to have heard of RMSF, were less likely to take preventive measures, indicating the need for improvement in early symptom recognition and prevention knowledge at the community level.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Article
Environmental Sciences
Andrew J. Newman, Andrew J. Monaghan, Martyn P. Clark, Kyoko Ikeda, Lulin Xue, Ethan D. Gutmann, Jeffrey R. Arnold
Summary: The Arctic is warming faster than the global average, with varying impacts on snowfall and snowpack across different regions. There are significant changes in snow cover and snowfall fractional contributions during spring and fall seasons. Differences in climate reference and future regional climate model simulations are evident, particularly in areas of complex topography.
Article
Multidisciplinary Sciences
Mayra R. Tocto-Erazo, Jorge A. Espindola-Zepeda, Jose A. Montoya-Laos, Manuel A. Acuna-Zegarra, Daniel Olmos-Liceaga, Pablo A. Reyes-Castro, Gudelia Figueroa-Preciado
Article
Environmental Sciences
Guillaume Rohat, Olga Wilhelmi, Johannes Flacke, Andrew Monaghan, Jing Gao, Martin van Maarseveen, Hy Dao
Summary: As urban areas are increasingly impacted by extreme heat due to climate change, it is important to assess future urban heat-related health risks and design adaptation strategies. In the case of Houston, community-based adaptation strategies aiming to reduce social isolation have been shown to be the most effective and feasible across various plausible futures.
Article
Infectious Diseases
Micah B. Hahn, Shane Feirer, Andrew J. Monaghan, Robert S. Lane, Rebecca J. Eisen, Kerry A. Padgett, Maggi Kelly
Summary: This study predicts that the suitable habitat for Ixodes pacificus in California will expand in the future under different climate change scenarios, with the largest increases projected in northwestern and southern coastal regions. By the end of the century, a significant portion of federally-owned lands in the state is expected to become suitable habitat for this tick species.
TICKS AND TICK-BORNE DISEASES
(2021)
Article
Infectious Diseases
Mario Avila, Elodie A. Vajda, Eileen Jeffrey Gutierrez, Daragh A. Gibson, Mariela Mosquera Renteria, Nicholas Presley, Daniel O'Reilly, Timothy A. Burton, Allison Tatarsky, Neil F. Lobo
Summary: Government-led entomological surveillance in the Guna Yala region of Panama identified gaps in protection, insecticide resistance, and behavioral patterns of Anopheles vectors that contribute to persisting malaria transmission. These findings underscore the importance of continued and targeted entomological surveillance to inform malaria control strategies.
Article
Genetics & Heredity
Gordana Rasic, Neil F. Lobo, Eileen H. Jeffrey Gutierrez, Hector M. Sanchez C., John M. Marshall
Summary: As gene drive mosquito projects progress to field trials, monitoring requirements must be assessed to ensure effective introduction and detect unintended spread and resistance. Different monitoring needs exist for population replacement and suppression systems, and lessons can be learned from experiences with Wolbachia-infected mosquitoes and genetically sterile male mosquitoes. Optimal traps and sampling frequency are crucial for detecting and managing gene drive alleles, resistance, and non-functional effector genes.
FRONTIERS IN GENETICS
(2022)
Article
Engineering, Environmental
Benedetto Schiavo, Diana Meza-Figueroa, Efrain Vizuete-Jaramillo, Agustin Robles-Morua, Aracely Angulo-Molina, Pablo A. Reyes-Castro, Claudio Inguaggiato, Belem Gonzalez-Grijalva, Martin Pedroza-Montero
Summary: This research examines the connection between metals associated with oxidative stress (OS) in urban dust and public health. The study also investigates the impact of seasonal variations on the dust's oxidative potential (OP) and the occurrence of diseases affected by OS. The findings highlight the importance of studying dust as an environmental factor that may potentially increase oxidative stress.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Article
Green & Sustainable Science & Technology
Efrain Vizuete-Jaramillo, Diana Meza-Figueroa, Pablo A. Reyes-Castro, Agustin Robles-Morua
Summary: The Getis-Ord G(i)* statistic clustering technique was used to create a hot spot exposure map of potentially toxic elements (PTEs) in urban dust samples in a semiarid city in northwest Mexico. The results of the sensitivity analysis showed that flood zones and pervious and impervious zones were the most influential variables. This study provides an effective tool for assessing environmental vulnerability in the region.
Article
Infectious Diseases
Mario I. I. avila, Elodie A. Vajda, Eileen Jeffrey Gutierrez, Daragh Gibson, Mariela Mosquera Renteria, Nicolas Presley, Daniel O'Reilly, Allison Tatarsky, Neil F. F. Lobo
Summary: This study used an Entomological Surveillance Planning Tool (ESPT) to investigate malaria transmission in the Guna Yala region of Panama. The results showed that there are localized foci of transmission and identified gaps in protection. The data from human behavior observations and mosquito sampling were integrated to guide local vector control decision-making.
Article
Parasitology
Eileen H. Jeffrey Gutierrez, M. A. Riehle, K. R. Walker, K. C. Ernst, G. Davidowitz
Summary: This study examines the utility of using body size as an entomological index to monitor the age structure of Aedesaegypti mosquitoes. The results show that body size itself is not significantly associated with age, but temperature, body size, female abundance, and relative humidity have a significant impact on age. Additionally, the study finds that age variation is greater within cities than between cities.
PARASITES & VECTORS
(2022)
Article
Virology
Kacey C. Ernst, Kathleen R. Walker, A. Lucia Castro-Luque, Chris Schmidt, Teresa K. Joy, Maureen Brophy, Pablo Reyes-Castro, Rolando Enrique Diaz-Caravantes, Veronica Ortiz Encinas, Alfonso Aguilera, Mercedes Gameros, Rosa Elena Cuevas Ruiz, Mary H. Hayden, Gerardo Alvarez, Andrew Monaghan, Daniel Williamson, Josh Arnbrister, Eileen Jeffrey Gutierrez, Yves Carriere, Michael A. Riehle
Summary: Dengue transmission is influenced by various factors such as environment, Aedes aegypti mosquitoes, dengue viruses, and humans. Mosquito sampling was conducted in multiple urban areas in the Arizona-Sonora desert region to study the factors affecting disease transmission. The abundance of potential vectors, mosquito age, and site-specific temperature were analyzed to estimate disease transmission. Results showed differences in vector abundance between endemic and non-endemic regions, with Tucson, Arizona having a higher estimated abundance than dengue endemic regions in Mexico.
Article
Multidisciplinary Sciences
Andrea L. Smidler, James J. Pai, Reema A. Apte, C. Hector M. Sanchez, Rodrigo M. Corder, Eileen Jeffrey Gutierrez, Neha Thakre, Igor Antoshechkin, John M. Marshall, Omar S. Akbari
Summary: Malaria is a deadly disease that mainly affects Sub-Saharan Africa, causing over half a million deaths annually. Controlling the mosquito vector Anopheles gambiae is an effective method to control disease spread. In this study, a genetic population suppression system called Ifegenia was developed to interrupt the deadly vector's reproduction. The Ifegenia males were shown to be reproductively viable and capable of passing on genetic mutations to suppress the population. Modeling demonstrated that releasing nonbiting Ifegenia males iteratively can be an effective, controllable, and safe method for population suppression and elimination.
