Combined probiotics attenuate chronic unpredictable mild stress-induced depressive-like and anxiety-like behaviors in rats

A combination of cecum microbiome and metabolome in CUMS depressed rats reveals the antidepressant mechanism of traditional Chinese medicines: A case study of Xiaoyaosan

(2021) Meng Lv et al.   JOURNAL OF ETHNOPHARMACOLOGY

Increased efficacy of combining prebiotic and postbiotic in mouse models relevant to autism and depression

(2021) Antonio Leo et al.   NEUROPHARMACOLOGY

Oral administration of Lactococcus lactis WHH2078 alleviates depressive and anxiety symptoms in mice with induced chronic stress

(2021) Kan Gao et al.   Food & Function

Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients

(2020) Leonilde Bonfrate et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The gut microbiome modulates gut–brain axis glycerophospholipid metabolism in a region-specific manner in a nonhuman primate model of depression

(2020) Peng Zheng et al.   MOLECULAR PSYCHIATRY

Scaffold hopping of agomelatine leads to enhanced antidepressant effects by modulation of gut microbiota and host immune responses

(2020) Qi An et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Glycated milk protein fermented with Lactobacillus rhamnosus ameliorates the cognitive health of mice under mild-stress condition

(2020) Nam Su Oh et al.   Gut Microbes

Probiotic Clostridium Butyricum Ameliorated Motor Deficits in a Mouse Model of Parkinson's Disease via Gut Microbiota-GLP-1 Pathway

(2020) Jing Sun et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of combined chronic predictable and unpredictable stress on depression-like symptoms in mice

(2020) Yajun Qiao et al.   Annals of Translational Medicine

Xiaoyaosan improves depressive-like behavior in rats with chronic immobilization stress through modulation of the gut microbiota

(2019) Hui-Zheng Zhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis

(2019) Nannan Li et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like behavior in rats

(2019) Zikai Hao et al.   PSYCHONEUROENDOCRINOLOGY

Pharmacokinetic considerations for current state-of-the-art antidepressants

(2019) Elżbieta Wyska   Expert Opinion on Drug Metabolism & Toxicology

Uncovering pharmacological mechanisms of Zhi-Zi-Hou-Po decoction in chronic unpredictable mild stress induced rats through pharmacokinetics, monoamine neurotransmitter and neurogenesis

(2019) Hang Xing et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidepressant effects of a polysaccharide from okra (Abelmoschus esculentus (L) Moench) by anti-inflammation and rebalancing the gut microbiota

(2019) Tingxu Yan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gut microbiome and depression: what we know and what we need to know

(2018) Gal Winter et al.   REVIEWS IN THE NEUROSCIENCES

Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo-controlled trial

(2018) R F Slykerman et al.   ACTA PAEDIATRICA

Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis

(2018) Jing Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chronic Unpredictable Mild Stress for Modeling Depression in Rodents:Meta-analysis of Model Reliability

(2018) Svitlana Antoniuk et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome

(2017) Maria Ines Pinto-Sanchez et al.   GASTROENTEROLOGY

Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics

(2017) Meng Yu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

New evidences on the altered gut microbiota in autism spectrum disorders

(2017) Francesco Strati et al.   Microbiome

Characterization of the anti-inflammatory Lactobacillus reuteri BM36301 and its probiotic benefits on aged mice

(2016) Joon Lee et al.   BMC MICROBIOLOGY

Lactobacillus acidophilus alleviates the inflammatory response to enterotoxigenic Escherichia coli K88 via inhibition of the NF-κB and p38 mitogen-activated protein kinase signaling pathways in piglets

(2016) Haihua Li et al.   BMC MICROBIOLOGY

Inflammation in Depression and the Potential for Anti-Inflammatory Treatment

(2016) Ole Kohler et al.   Current Neuropharmacology

Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder

(2016) Emiko Aizawa et al.   JOURNAL OF AFFECTIVE DISORDERS

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Role of neuromediators in the functioning of the human microbiota: “Business talks” among microorganisms and the microbiota-host dialogue

(2016) A. V. Oleskin et al.   MICROBIOLOGY

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

(2016) P Zheng et al.   MOLECULAR PSYCHIATRY

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

(2016) Meysam Pirbaglou et al.   NUTRITION RESEARCH

Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats

(2016) Mariusz Papp et al.   PSYCHOPHARMACOLOGY

The Probiotics in Pregnancy Study (PiP Study): rationale and design of a double-blind randomised controlled trial to improve maternal health during pregnancy and prevent infant eczema and allergy

(2016) Christine Barthow et al.   BMC Pregnancy and Childbirth

Mood by microbe: towards clinical translation

(2016) Timothy G. Dinan et al.   Genome Medicine

Dendritic Spines in Depression: What We Learned from Animal Models

(2016) Hui Qiao et al.   NEURAL PLASTICITY

Integrated Role of Bifidobacterium animalis subsp. lactis Supplementation in Gut Microbiota, Immunity, and Metabolism of Infant Rhesus Monkeys

(2016) Xuan He et al.   mSystems

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Gastrointestinal microbiota in children with autism in Slovakia

(2015) Aleksandra Tomova et al.   PHYSIOLOGY & BEHAVIOR

The Gut-Brain Axis: The Missing Link in Depression

(2015) Alper Evrensel et al.   Clinical Psychopharmacology and Neuroscience

Mental health: A world of depression

(2014) Kerri Smith   NATURE

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Changes in regional cerebral blood flow with Chaihu-Shugan-San in the treatment of major depression

(2014) Sui-Yu Hu et al.   Pharmacognosy Magazine

Psychobiotics: A Novel Class of Psychotropic

(2013) Timothy G. Dinan et al.   BIOLOGICAL PSYCHIATRY

Early supplementation withLactobacillus rhamnosus HN001 reduces eczema prevalence to 6 years: does it also reduce atopic sensitization?

(2013) K. Wickens et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Melancholic microbes: a link between gut microbiota and depression?

(2013) T. G. Dinan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Stressful life events and neuroticism as predictors of late-life versus early-life depression

(2013) Kerstin Weber et al.   Psychogeriatrics

Gut–brain axis: how the microbiome influences anxiety and depression

(2013) Jane A. Foster et al.   TRENDS IN NEUROSCIENCES

A protective effect of Lactobacillus rhamnosusHN001 against eczema in the first 2 years of life persists to age 4 years

(2012) K. Wickens et al.   CLINICAL AND EXPERIMENTAL ALLERGY

On communication between gut microbes and the brain

(2012) Paul Forsythe et al.   CURRENT OPINION IN GASTROENTEROLOGY

An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota

(2011) Ian B Jeffery et al.   GUT

Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

(2011) Brent L. Williams et al.   PLoS One

The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?

(2010) G MacQueen et al.   MOLECULAR PSYCHIATRY

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

(2010) L. Desbonnet et al.   NEUROSCIENCE

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

A differential effect of 2 probiotics in the prevention of eczema and atopy: A double-blind, randomized, placebo-controlled trial

(2008) Kristin Wickens et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat

(2008) Lieve Desbonnet et al.   JOURNAL OF PSYCHIATRIC RESEARCH