A novelent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF

(2014) Jurian Schuijers et al.   EMBO JOURNAL

ATF4 and N-Myc coordinate glutamine metabolism inMYCN-amplified neuroblastoma cells through ASCT2 activation

(2014) Ping Ren et al.   JOURNAL OF PATHOLOGY

N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation

(2014) Guoli Guo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin analogue T83 exhibits potent antitumor activity and induces radiosensitivity through inactivation of Jab1 in nasopharyngeal carcinoma

(2013) Yunbao Pan et al.   BMC CANCER

The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin

(2013) Quan Wang et al.   BMC CANCER

Cytotoxic ent-Kaurane Diterpenoids from Salvia cavaleriei

(2013) Heng Zheng et al.   JOURNAL OF NATURAL PRODUCTS

Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction

(2013) Sheng Wang et al.   Nature Chemical Biology

Activating Transcription Factor 4 and X Box Binding Protein 1 of Litopenaeus vannamei Transcriptional Regulated White Spot Syndrome Virus Genes Wsv023 and Wsv083

(2013) Xiao-Yun Li et al.   PLoS One

Curcumin potentiates the antitumor effects of 5-FU in treatment of esophageal squamous carcinoma cells through downregulating the activation of NF- B signaling pathway in vitro and in vivo

(2012) F. Tian et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives

(2012) Ahmad F. Eweas et al.   BIOORGANIC CHEMISTRY

ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation

(2012) Guoliang Qing et al.   CANCER CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Drugging Wnt signalling in cancer

(2012) Paul Polakis   EMBO JOURNAL

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Modulation of Wnt/ -catenin signaling pathway by bioactive food components

(2011) R. S. Tarapore et al.   CARCINOGENESIS

Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1 

(2010) G. Qing et al.   CANCER RESEARCH

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Notch dimerization is required for leukemogenesis and T-cell development

(2010) H. Liu et al.   GENES & DEVELOPMENT

Colorectal cancer

(2010) David Cunningham et al.   LANCET

Isolation and analysis of bioactive diterpenoids in Salvia species (Salvia chionantha and Salvia kronenburgiii) by micellar electrokinetic capillary chromatography

(2009) Nevin Öztekin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE