Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates

Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

(2021) Joana Ribeiro et al.   Cell Reports

Low Immunogenicity and Immunosuppressive Properties of Human ESC- and iPSC-Derived Retinas

(2021) Suguru Yamasaki et al.   Stem Cell Reports

Genetically engineered stem cell-derived retinal grafts for improved retinal reconstruction after transplantation

(2021) Take Matsuyama et al.   iScience

A Genetic modification that reduces ON-bipolar cells in hESC-derived retinas enhances functional integration after transplantation

(2021) Suguru Yamasaki et al.   iScience

Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue

(2019) Atsushi Kuwahara et al.   Scientific Reports

Retinal microglia – A key player in healthy and diseased retina

(2018) Gurugirijha Rathnasamy et al.   PROGRESS IN NEUROBIOLOGY

Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation

(2018) Satoshi Iraha et al.   Stem Cell Reports

Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner

(2018) Paul V. Waldron et al.   Stem Cell Reports

Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration

(2018) Hung-Ya Tu et al.   EBioMedicine

A Reinterpretation of Cell Transplantation: GFP Transfer From Donor to Host Photoreceptors

(2017) Arturo Ortin-Martinez et al.   STEM CELLS

Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions

(2017) Sacha Reichman et al.   STEM CELLS

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

(2017) Asuka Morizane et al.   Nature Communications

iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice

(2017) Michiko Mandai et al.   Stem Cell Reports

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

(2016) Xu Wang et al.   JOURNAL OF NEUROSCIENCE

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

(2016) Yuji Shiba et al.   NATURE

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors

(2016) R. A. Pearson et al.   Nature Communications

Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange

(2016) Tiago Santos-Ferreira et al.   Nature Communications

Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models

(2016) Sunao Sugita et al.   Stem Cell Reports

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice

(2016) Alona O. Barnea-Cramer et al.   Scientific Reports

Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing

(2015) Takashi Shiina et al.   IMMUNOGENETICS

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration

(2015) Hiroshi Shirai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue

(2015) Atsushi Kuwahara et al.   Nature Communications

A new immunodeficient pigmented retinal degenerate rat strain to study transplantation of human cells without immunosuppression

(2014) Magdalene J. Seiler et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

(2014) Xiufeng Zhong et al.   Nature Communications

Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice

(2014) Juthaporn Assawachananont et al.   Stem Cell Reports

The major histocompatibility complex: a model for understanding graft-versus-host disease

(2013) E. W. Petersdorf   BLOOD

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

(2013) Anai Gonzalez-Cordero et al.   NATURE BIOTECHNOLOGY

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation

(2013) M. S. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Migration, Integration and Maturation of Photoreceptor Precursors Following Transplantation in the Mouse Retina

(2013) Katherine Warre-Cornish et al.   STEM CELLS AND DEVELOPMENT

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Restoration of vision after transplantation of photoreceptors

(2012) R. A. Pearson et al.   NATURE

The Expression Patterns of MHC Class I Molecules in the Developmental Human Visual System

(2012) Aifeng Zhang et al.   NEUROCHEMICAL RESEARCH

Repair of the degenerate retina by photoreceptor transplantation

(2012) A. C. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

(2011) Jason S. Meyer et al.   STEM CELLS