Atovaquone attenuates experimental colitis by reducing neutrophil infiltration of colonic mucosa

Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

(2021) Jacob F. Rehring et al.   Frontiers in Immunology

Early Change in Epithelial Neutrophilic Infiltrate Predicts Long-Term Response to Biologics in Ulcerative Colitis

(2021) Neeraj Narula et al.   Clinical Gastroenterology and Hepatology

Inflammatory Bowel Disease and Risk of Colorectal Cancer: An Overview From Pathophysiology to Pharmacological Prevention

(2021) Marianna Lucafò et al.   Frontiers in Pharmacology

Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern

(2021) Madalina Elena Carter-Timofte et al.   ACS Infectious Diseases

Editorial: Targeting Leukocyte Trafficking: Insights and Future Directions

(2021) Ronen Sumagin et al.   Frontiers in Immunology

Changing Global Epidemiology of Inflammatory Bowel Diseases—Sustaining Healthcare Delivery into the 21st Century

(2020) Ashwin N. Ananthakrishnan et al.   Clinical Gastroenterology and Hepatology

Positioning therapies in ulcerative colitis

(2020) Silvio Danese et al.   Clinical Gastroenterology and Hepatology

S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis

(2020) Ninecia R. Scott et al.   JOURNAL OF CLINICAL INVESTIGATION

Controlling leukocyte trafficking in IBD

(2020) Marisol Veny et al.   PHARMACOLOGICAL RESEARCH

Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

(2019) Veronika Butin-Israeli et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil transendothelial migration: updates and new perspectives

(2019) Marie-Dominique Filippi   BLOOD

Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?

(2018) Carlos Rosales   Frontiers in Physiology

In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines

(2018) David P. Sullivan et al.   Mucosal Immunology

Recruitment of activated neutrophils correlates with disease severity in adult Crohn’s disease

(2018) A. Therrien et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Potential roles of neutrophils in regulating intestinal mucosal inflammation of inflammatory bowel disease

(2017) Guang Xi Zhou et al.   Journal of Digestive Diseases

Neutrophil Microparticles Deliver Active Myeloperoxidase to Injured Mucosa To Inhibit Epithelial Wound Healing

(2017) Thomas W. Slater et al.   JOURNAL OF IMMUNOLOGY

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database

(2017) Xia Wang et al.   NUCLEIC ACIDS RESEARCH

Therapeutic effect of hydroxychloroquine on colorectal carcinogenesis in experimental murine colitis

(2016) Junlin Yao et al.   BIOCHEMICAL PHARMACOLOGY

Deposition of microparticles by neutrophils onto inflamed epithelium: a new mechanism to disrupt epithelial intercellular adhesions and promote transepithelial migration

(2016) Veronika Butin-Israeli et al.   FASEB JOURNAL

Enhancing the Enrichment of Pharmacophore-Based Target Prediction for the Polypharmacological Profiles of Drugs

(2016) Xia Wang et al.   Journal of Chemical Information and Modeling

Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells

(2016) Marco Fiorillo et al.   Oncotarget

Neutrophil Extracellular Traps in Ulcerative Colitis

(2015) Tue Bjerg Bennike et al.   INFLAMMATORY BOWEL DISEASES

Granule Protein Processing and Regulated Secretion in Neutrophils

(2014) Avinash Sheshachalam et al.   Frontiers in Immunology

Neutrophil Transmigration: Emergence of an Adhesive Cascade within Venular Walls

(2013) Mathieu-Benoit Voisin et al.   Journal of Innate Immunity

Transmigrated neutrophils in the intestinal lumen engage ICAM-1 to regulate the epithelial barrier and neutrophil recruitment

(2013) R Sumagin et al.   Mucosal Immunology

Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules

(2012) S. Kumar et al.   BLOOD

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine

(2012) Duke Geem et al.   Jove-Journal of Visualized Experiments

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

(2010) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling

(2009) K. Szczur et al.   BLOOD