Modification of phosphoinositides by the Shigella effector IpgD during host cell infection

The type 3 secretion effector IpgD promotes S. flexneri dissemination

(2022) Volkan K. Köseoğlu et al.   PLoS Pathogens

Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase

(2022) Glenn F. W. Walpole et al.   NATURE CELL BIOLOGY

The Shigella Type III Secretion System: An Overview from Top to Bottom

(2021) Meenakumari Muthuramalingam et al.   Microorganisms

New methods to decrypt emerging macropinosome functions during the host–pathogen crosstalk

(2021) Yuen‐Yan Chang et al.   CELLULAR MICROBIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Purification of infection-associated macropinosomes by magnetic isolation for proteomic characterization

(2021) Virginie Stévenin et al.   Nature Protocols

Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection

(2020) Sonja Kühn et al.   Cell Reports

Transcytosis subversion by M cell-to-enterocyte spread promotes Shigella flexneri and Listeria monocytogenes  intracellular bacterial dissemination

(2020) Camille Rey et al.   PLoS Pathogens

Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape

(2020) Yuen-Yan Chang et al.   PLoS Pathogens

NAIP-NLRC4-deficient mice are susceptible to shigellosis

(2020) Patrick S Mitchell et al.   eLife

Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection

(2019) Alexandre Grassart et al.   Cell Host & Microbe

Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche

(2019) Virginie Stévenin et al.   Cell Reports

TMEM55a localizes to macrophage phagosomes to downregulate phagocytosis

(2018) Shin Morioka et al.   JOURNAL OF CELL SCIENCE

Identification of interactions among host and bacterial proteins and evaluation of their role early during Shigella flexneri infection

(2018) Kelly A. Miller et al.   MICROBIOLOGY-SGM

Nε-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function

(2018) Wang Liu et al.   Nature Microbiology

The Pathogen–Host Interface in Three Dimensions: Correlative FIB/SEM Applications

(2018) Allon Weiner et al.   TRENDS IN MICROBIOLOGY

Principles of intracellular bacterial pathogen spread from cell to cell

(2018) Erin Weddle et al.   PLoS Pathogens

MYO6 is targeted bySalmonellavirulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells

(2017) Andrew B. E. Brooks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A systematic exploration of the interactions between bacterial effector proteins and host cell membranes

(2017) Bethany A. Weigele et al.   Nature Communications

PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment

(2016) Frédéric Boal et al.   Cell Reports

Macropinosomes are Key Players in Early Shigella Invasion and Vacuolar Escape in Epithelial Cells

(2016) Allon Weiner et al.   PLoS Pathogens

Modification of Bacterial Effector Proteins Inside Eukaryotic Host Cells

(2016) Crina M. Popa et al.   Frontiers in Cellular and Infection Microbiology

The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis

(2015) FoSheng Hsu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphoinositides and host–pathogen interactions

(2015) Javier Pizarro-Cerdá et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma

(2015) Tiziana Scanu et al.   Cell Host & Microbe

Cytoskeletal mechanics duringShigellainvasion and dissemination in epithelial cells

(2015) Cesar M. Valencia-Gallardo et al.   CELLULAR MICROBIOLOGY

Dual 4- and 5-phosphatase activities regulate SopB-dependent phosphoinositide dynamics to promote bacterial entry

(2015) Heather L. Piscatelli et al.   CELLULAR MICROBIOLOGY

TOM1 is a PI5P effector involved in the regulation of endosomal maturation

(2015) F. Boal et al.   JOURNAL OF CELL SCIENCE

Shigella flexneri Regulation of ARF6 Activation during Bacterial Entry via an IpgD-Mediated Positive Feedback Loop

(2015) Anna Cristina Garza-Mayers et al.   mBio

Shigella Subverts the Host Recycling Compartment to Rupture Its Vacuole

(2014) Nora Mellouk et al.   Cell Host & Microbe

Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1

(2014) Julien Viaud et al.   Nature Communications

A Shigella Effector Dampens Inflammation by Regulating Epithelial Release of Danger Signal ATP through Production of the Lipid Mediator PtdIns5P

(2013) Andrea Puhar et al.   IMMUNITY

Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ

(2013) Nikolay Burnaevskiy et al.   NATURE

Arf6 coordinates actin assembly through the WAVE complex, a mechanism usurped by Salmonella to invade host cells

(2013) D. Humphreys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin-based confinement of calcium responses during Shigella invasion

(2013) Guy Tran Van Nhieu et al.   Nature Communications

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

(2012) Amin Tahoun et al.   Cell Host & Microbe

Salmonella Virulence Effector SopE and Host GEF ARNO Cooperate to Recruit and Activate WAVE to Trigger Bacterial Invasion

(2012) Daniel Humphreys et al.   Cell Host & Microbe

The Shigella flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism

(2011) Christoph Konradt et al.   Cell Host & Microbe

Protective Role of Akt2 in Salmonella enterica Serovar Typhimurium-Induced Gastroenterocolitis

(2011) Winnie W. S. Kum et al.   INFECTION AND IMMUNITY

Activation of Akt by the Bacterial Inositol Phosphatase, SopB, is Wortmannin Insensitive

(2011) Kendal G. Cooper et al.   PLoS One

Shigella flexneri Infection Generates the Lipid PI5P to Alter Endocytosis and Prevent Termination of EGFR Signaling

(2011) D. Ramel et al.   Science Signaling

Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole

(2010) Virginie Braun et al.   CELLULAR MICROBIOLOGY

Diversification of a Salmonella Virulence Protein Function by Ubiquitin-Dependent Differential Localization

(2009) Jayesh C. Patel et al.   CELL

Requirement for Formin-Induced Actin Polymerization during Spread of Shigella flexneri

(2009) J. E. Heindl et al.   INFECTION AND IMMUNITY

Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection

(2008) M. V. Bujny et al.   JOURNAL OF CELL SCIENCE

IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri

(2007) Abderrahman Hachani et al.   MICROBES AND INFECTION