A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response

(2019) Felipe J. Núñez et al.   Science Translational Medicine

Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma

(2019) Weikun Xiao et al.   MATRIX BIOLOGY

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

(2018) Amelie Griveau et al.   CANCER CELL

Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial

(2016) Mustafa Khasraw et al.   JOURNAL OF NEURO-ONCOLOGY

GlioVis data portal for visualization and analysis of brain tumor expression datasets

(2016) Robert L. Bowman et al.   NEURO-ONCOLOGY

Large-scale assessment of the gliomasphere model system

(2016) Dan R. Laks et al.   NEURO-ONCOLOGY

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

(2015) A. Scholz et al.   EMBO Molecular Medicine

Enhanced expression of CD31/platelet endothelial cell adhesion molecule 1 (PECAM1) correlates with hypoxia inducible factor-1 alpha (HIF-1α) in human glioblastoma multiforme

(2015) Giuseppe Musumeci et al.   EXPERIMENTAL CELL RESEARCH

Targeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicityin vivo

(2015) Virginie Lamour et al.   INTERNATIONAL JOURNAL OF CANCER

Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma

(2015) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Aggressive invasion is observed in CD133−/A2B5+ glioma-initiating cells

(2015) TING SUN et al.   Oncology Letters

Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition

(2015) Shanmugarajan Krishnan et al.   Oncotarget

Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression

(2014) H.-M. Jeon et al.   CANCER RESEARCH

Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway

(2014) Guang-Ning Yan et al.   JOURNAL OF PATHOLOGY

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

(2014) Roger Stupp et al.   LANCET ONCOLOGY

Angiogenesis in Glioblastoma

(2013) Sunit Das et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Differences between Normal and Glioma-Derived Glial Progenitor Cells Identify a Core Set of Dysregulated Genes

(2013) Romane M. Auvergne et al.   Cell Reports

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

(2012) Lothar C Dieterich et al.   JOURNAL OF PATHOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

The perivascular niche microenvironment in brain tumor progression

(2010) Nikki A Charles et al.   CELL CYCLE

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells

(2010) Nikki Charles et al.   Cell Stem Cell

A2B5 Cells from Human Glioblastoma have Cancer Stem Cell Properties

(2009) Aurélie Tchoghandjian et al.   BRAIN PATHOLOGY

Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma

(2009) Dan R. Laks et al.   STEM CELLS

Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis

(2008) Luc Malaval et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IDENTIFICATION OF A2B5+CD133− TUMOR-INITIATING CELLS IN ADULT HUMAN GLIOMAS

(2008) Alfred T. Ogden et al.   NEUROSURGERY