MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
Authors
Keywords
-
Journal
Cell Reports
Volume 41, Issue 1, Pages 111445
Publisher
Elsevier BV
Online
2022-10-04
DOI
10.1016/j.celrep.2022.111445
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting MCL-1 in cancer: current status and perspectives
- (2021) Haolan Wang et al. Journal of Hematology & Oncology
- Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics.
- (2020) Devin K. Schweppe et al. JOURNAL OF PROTEOME RESEARCH
- TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples
- (2020) Jiaming Li et al. NATURE METHODS
- MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions
- (2020) Ujval Anilkumar et al. Cell Death & Disease
- Pairing MCL‐1 inhibition with venetoclax improves therapeutic efficiency of BH3‐mimetics in AML
- (2020) Myriam Hormi et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition
- (2020) Bing Z. Carter et al. HAEMATOLOGICA
- Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer
- (2019) Taekyu Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- The landscape of cancer cell line metabolism
- (2019) Haoxin Li et al. NATURE MEDICINE
- GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
- (2019) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer
- (2019) Marteinn Thor Snaebjornsson et al. Cell Metabolism
- VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis
- (2018) MacIntosh Cornwell et al. BMC BIOINFORMATICS
- Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3
- (2018) José Navarrete-Perea et al. JOURNAL OF PROTEOME RESEARCH
- Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD
- (2018) Silvia Escudero et al. MOLECULAR CELL
- Fatty acid oxidation: An emerging facet of metabolic transformation in cancer
- (2018) Yibao Ma et al. CANCER LETTERS
- Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes
- (2017) Nora Raulien et al. Frontiers in Immunology
- Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources
- (2016) Joao A. Paulo et al. Journal of Proteomics
- PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
- (2016) Natalie J. German et al. MOLECULAR CELL
- The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
- (2016) András Kotschy et al. NATURE
- Targeting metastasis-initiating cells through the fatty acid receptor CD36
- (2016) Gloria Pascual et al. NATURE
- Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia
- (2016) Andrew W. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- Defining specificity and on-target activity of BH3-mimetics using engineered B-ALL cell lines
- (2016) Brian Koss et al. Oncotarget
- A Deeper Look into Comet—Implementation and Features
- (2015) Jimmy K. Eng et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins
- (2015) Alfredo Giménez-Cassina et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes
- (2014) Graeme C. McAlister et al. ANALYTICAL CHEMISTRY
- Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1
- (2014) B. Faubert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia
- (2013) B. Koss et al. BLOOD
- Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
- (2013) Edward Y Chen et al. BMC BIOINFORMATICS
- Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction
- (2013) X. Wang et al. GENES & DEVELOPMENT
- The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and selected ion monitoring GC/MS
- (2013) Orval Mamer et al. Metabolomics
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inhibition of PPARα Induces Cell Cycle Arrest and Apoptosis, and Synergizes with Glycolysis Inhibition in Kidney Cancer Cells
- (2013) Omran Abu Aboud et al. PLoS One
- Increasing the Multiplexing Capacity of TMTs Using Reporter Ion Isotopologues with Isobaric Masses
- (2012) Graeme C. McAlister et al. ANALYTICAL CHEMISTRY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma
- (2012) Pilar Caro et al. CANCER CELL
- AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
- (2012) Brandon Faubert et al. Cell Metabolism
- Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
- (2012) Rhonda M. Perciavalle et al. NATURE CELL BIOLOGY
- NCBI GEO: archive for functional genomics data sets—update
- (2012) Tanya Barrett et al. NUCLEIC ACIDS RESEARCH
- Comet: An open-source MS/MS sequence database search tool
- (2012) Jimmy K. Eng et al. PROTEOMICS
- High-Throughput, Accurate Mass Metabolome Profiling of Cellular Extracts by Flow Injection–Time-of-Flight Mass Spectrometry
- (2011) Tobias Fuhrer et al. ANALYTICAL CHEMISTRY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
- (2011) Lily Ting et al. NATURE METHODS
- Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells
- (2011) Yuexi Wang et al. PROTEOMICS
- Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
- (2011) T. N. Chonghaile et al. SCIENCE
- BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore
- (2011) Loren D. Walensky et al. TRENDS IN BIOCHEMICAL SCIENCES
- Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1
- (2010) D. Yecies et al. BLOOD
- A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
- (2010) Edward L. Huttlin et al. CELL
- The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity
- (2010) Chi-Ruei Huang et al. FEBS LETTERS
- The landscape of somatic copy-number alteration across human cancers
- (2010) Rameen Beroukhim et al. NATURE
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Mcl-1 is a potential therapeutic target in multiple types of cancer
- (2008) C. Akgul CELLULAR AND MOLECULAR LIFE SCIENCES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started