Article
Chemistry, Physical
Han Zhao, Wanli Kang, Hongbin Yang, Zitong Huang, Bobo Zhou
Summary: The study showed that the combination system of amphiphilic polymer and surfactant exhibited better emulsifying ability and emulsion stability compared to using either component alone. The improvement was attributed to the low interfacial tension generated by the addition of surfactant, as well as higher external viscosity and stronger interfacial film strength in the emulsion formed by the combination system. These factors collectively slowed down emulsion droplet migration velocity and prevented droplet coalescence, ultimately increasing emulsion stability.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Multidisciplinary
Dongju Li, Bingkun Gao, Xiangyu Cui
Summary: In this study, the main factors affecting the emulsifying stability of flowback fluids from acidizing oil wells in the DaQing oilfield of China were investigated using a high-speed emulsifier and electric dehydrator. The study explored the effects of various components on the emulsion stability, including inorganic salts, solid nanoparticles, polymers, and surfactants. The results showed that sodium chloride had the best ability to maintain the stability of the emulsion, and the effect of ferrous sulfide nanoparticles was higher than that of silica nanoparticles and calcium carbonate nanoparticles. The study also clarified the mechanism of multi-factor synergistic emulsification. These findings are of great significance to the efficient treatment of oilfield-produced fluids and environmental protection.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Engineering, Chemical
Rajesh K. Saini, Brady Crane, Nicole R. Shimek, Weiran Wang, Brent Cooper
Summary: The development of nano-emulsion based flowback aids has been effective in reducing water saturation, minimizing formation damage, enhancing productivity, and proving beneficial for low permeability oil reservoirs in tight formations.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Energy & Fuels
Xiaoxiao Li, Xiang'an Yue, Zhen Wang, Rongjie Yan, Yabing Guo
Summary: The study revealed that increasing flow rate can facilitate oil film detachment, but the effectiveness is limited by the action area and displacement efficiency. Different surfactants with varying interfacial tensions and emulsification behaviors were found to promote the dislodging of the oil film.
Article
Energy & Fuels
Zhanqing Qu, Jiwei Wang, Tiankui Guo, Lin Shen, Hualin Liao, Xiaoqiang Liu, Jiacheng Fan, Tong Hao
Summary: This study integrated a comprehensive flowback model of fracturing fluid by combining a modified proppant sedimentation velocity calculation model, a critical proppant regurgitation velocity calculation model, and a wellhead pressure calculation model. By establishing an optimization model of fracturing fluid flowback with specific criteria, the study was able to improve efficiency and reduce proppant settlement in fractured wells. The model was verified with data from fractured wells in DaQing Oilfield, showing promising results with average errors of 11.9% for wellhead pressure and 11.6% for flowback flowrate. Additionally, parametric analysis revealed the effects of factors such as reservoir permeability, reservoir porosity, fracturing fluid density, and proppant particle size on flowback efficiency and proppant settlement degree.
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Yu Li, Huiqing Liu, Qing Wang, Xiaohu Dong, Xin Chen
Summary: The new polymer viscosity reducer enhances heavy oil reservoir development through five microscopic processes in a visual filling model, influencing the interfacial properties of oil, water, and rock, improving flow efficiency, and increasing oil recovery rates.
Article
Environmental Sciences
Joanna Fajfer, Olga Lipinska, Monika Konieczynska
Summary: This passage discusses the chemical characteristics of flowback fluids from hydraulic fracturing for shale gas exploration/production, showing that the variability in their chemical composition is significant at different locations, depending on the sampling schedule.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Sanjana Krishna Mani, Sulaiman Al-Tooqi, Jiaqi Song, Aditya Sapre, Lauren D. Zarzar, Ayusman Sen
Summary: The interplay of interfacial tensions on droplets leads to self-powered oscillating motions, which can mimic the behavior of living systems. This study investigates the rapid oscillations observed in oil-in-water emulsions and explores the factors influencing these oscillations.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Energy & Fuels
Yujie Bai, Guangsheng Cao, Xiaohan Nan, Shining Li, Hongxin An, Xin Wang, Zhe Wang
Summary: The addition of sodium fluosilicate particles can significantly improve the stability of emulsions in acidified flowback fluid, but also hinder electric dehydration treatment. Increasing the experimental temperature can enhance the effect of electric dehydration for crude oil samples with high gum and asphaltene contents.
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Ying Li, Maosen Wang, Yinghui An, Kaijun Li, Zhaojie Wei, Kun Bo, Pinlu Cao, Mingyi Guo
Summary: In this study, an oil-in-water nanoemulsion was explored as a potential strategy for shale inhibition. The nanoemulsion formed a hydrophobic protective film on shale surfaces, which effectively maintained wellbore stability in high-temperature drilling operations. The results showed that the nanoemulsion had superior inhibition performance and resistance to elevated temperatures, and the shale surfaces treated with the nanoemulsion exhibited water repellency. The wettability of the film could be controlled by adjusting the ratio of different components in the nanoemulsion.
Article
Chemistry, Multidisciplinary
Mohamed Amen Hammami, Mazen Y. Kanj, Emmanuel P. Giannelis
Summary: Characterization of complex oil emulsions using flow cytometry revealed that the presence of specific ions significantly affects the properties of the emulsion, with different ions having varied effects on the charge of oil droplets. This study demonstrates the utility of flow cytometry as a new tool for characterizing oil emulsions in a variety of fields.
Article
Chemistry, Multidisciplinary
Bo Dong, Zongyu Qin, Yiwei Wang, Jiahui Zhang, Zhen Xu, Aixian Liu, Xuqiang Guo
Summary: This study investigates the performance of isooctyl glucoside as an emulsifier for a heavy crude oil-in-water emulsion and reveals that the viscosity and stability of the emulsion increase with increasing oil content, surfactant concentration, mixing speed, mixing time, and pH of the aqueous phase. The optimal parameters result in a significant reduction in viscosity and high stability of the emulsion.
Article
Chemistry, Physical
Rohit Kumar Saw, Pranali M. Rane, Dinesh Joshi, Shubham Prakash, Lavisha Jangid, Ajay Mandal
Summary: In recent years, there has been increasing interest in the application of natural surfactants in enhanced oil recovery (EOR) due to environmental concerns. This study introduces a novel non-ionic surfactant synthesized from olive oil and evaluates its properties. The synthesized surfactant showed effective emulsification, wettability modification, and efficient oil displacement. Additionally, the surfactant had a low critical micelle concentration, indicating its ability to reduce interfacial tension.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Energy & Fuels
Yingwei Si, Yangwen Zhu, Tao Liu, Xinru Xu, Jingyi Yang
Summary: In this study, a boron-containing anionic-nonionic surfactant (SYW) was synthesized and used for emulsification viscosity reduction research on Xinjiang heavy oil. SYW showed a viscosity reduction rate of 97.3%. By compounding SYW with oleic acid and ethanolamine, the resulting surfactant SYG further improved the viscosity reduction rate to 98.6%. Both SYW and SYG significantly reduced interfacial tension and improved the dispersion of the emulsion.
Article
Chemistry, Physical
Xuezhi Zhao, Fuxing Zhan, Guangzhi Liao, Weidong Liu, Xin Su, Yujun Feng
Summary: This study investigates the visualization of in situ generation of middle-phase microemulsion during surfactant enhanced oil recovery (EOR) and quantifies its contribution to the oil recovery factor.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Mathematics, Interdisciplinary Applications
Huiling Yuan, Yulei Sun, Lu Xu, Yong Zhou, Xiangyu Cui
Summary: This study introduces a new econometric model for volatility asymmetry and establishes its asymptotic properties. Through simulation studies, it is verified that the proposed model has better volatility forecasting performance than the GARCH-Ito model in the literature. A real data example further demonstrates the superior volatility prediction power of the new model.
JOURNAL OF TIME SERIES ANALYSIS
(2022)
Article
Management
Yun Shi, Duan Li, Xiangyu Cui
Summary: The dynamic mean-variance formulation in the market lacks time consistency in efficiency. A new policy, called the TCIE policy, is developed to address the truncated time-horizon problem and avoid irrational investment behaviors, achieving better overall investment performance compared to existing policies.
JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY
(2023)
Article
Energy & Fuels
Haoyuan Li, Qi Zhang, Zhenlu Li, Qiang Pang, Keying Wei, Yuan Zeng, Xiangyu Cui, Yushuang Zhu
Summary: In this paper, a semi-analytical mathematical model of pressure transient analysis (PTA) for MWFV in CBM reservoir is proposed, considering the complexity of porous media by introducing fractal geometry, the anomalous diffusion based on fractional calculus, and the stress sensitivity represented by the exponential expression. The solution of the bottom hole pressure is obtained using line source theory, dimensionless transformation, Pedrosa transformation, and other methods. The PTA curve is presented by the Stehfest inversion method, and seven flowing regimes are identified. The results provide better guidance to understand the CBM production performance in MWFV.
ENERGY EXPLORATION & EXPLOITATION
(2022)
Article
Engineering, Electrical & Electronic
Wendi Yan, Wei Liu, Chunlei Jiang, Zhen Huang, Kaichuan Xu, Taiji Dong, Xiangyu Cui, Dongfeng Yang
Summary: A micro Fabry-Perot interferometer based on a microsphere lens is proposed and experimentally demonstrated for motor rotation speed measurement. The experimental results show that the method has a relative error of less than 0.1%.
OPTICAL FIBER TECHNOLOGY
(2022)
Article
Operations Research & Management Science
Xiang-Yu Cui, Jian-Jun Gao, Xun Li, Yun Shi
Summary: This paper focuses on the time-consistency of dynamic mean-variance (MV) portfolio optimization problem, with a particular emphasis on the multi-period mean-variance (MMV) portfolio optimization problem. The time inconsistency issue is identified as a significant challenge in this field.
JOURNAL OF THE OPERATIONS RESEARCH SOCIETY OF CHINA
(2022)
Article
Biochemistry & Molecular Biology
Xiangyu Cui, Wenbo Wang, Mengcheng Du, Delong Ma, Xiaolai Zhang
Summary: Soluble sulfur promotes its dissolution in solvents through van der Waals interaction, while the interaction between polymer chains of insoluble sulfur hinders its diffusion in solvents.
Article
Optics
Hao Wu, Chunlei Jiang, Anning Ren, Taiji Dong, Xiangyu Cui
Summary: The manipulation of particles is important in various fields, and this study demonstrates a structure that allows for multi-wavelength excitation and the use of multi-mode beams for particle manipulation. Experimental results show the achievement of separate focus points and stable traps, as well as axial reciprocating transfer of particles between these points without moving the fiber.
OPTICS COMMUNICATIONS
(2022)
Article
Operations Research & Management Science
Xiangyu Cui, Duan Li, Yun Shi, Mingjia Zhu
Summary: In a multiperiod mean-variance framework, the issue of time inconsistency in investor decision-making is addressed. Current approaches either assume no self-control capability or assume sufficient self-control capability. However, in reality, investors often have limited self-control ability. This study formulates the problem as a planner-middleman-doer game and derives the explicit expression for equilibrium strategy.
OPTIMIZATION LETTERS
(2023)
Article
Statistics & Probability
Huiling Yuan, Yong Zhou, Zhiyuan Zhang, Xiangyu Cui
Summary: In this article, a model that integrates low-frequency historical data, high-frequency historical data, and option data for volatility forecasting is proposed. The model uses option-implied volatility extracted from option data and demonstrates better out-of-sample performance compared to other popular volatility models.
CANADIAN JOURNAL OF STATISTICS-REVUE CANADIENNE DE STATISTIQUE
(2023)
Article
Management
Yun Shi, Xiangyu Cui, Xun Yu Zhou
Summary: The security market line is usually flat or downward-sloping. We propose that probability weighting affects this relationship differently during periods of overweighting or underweighting extreme events. Overweighting inflates the probability of bad events and demands higher compensation for beta risk, while underweighting has the opposite effect. These effects offset each other when not considering probability weighting, resulting in a flat or slightly negative return-beta relationship. Our three-moment conditional capital asset pricing model for a market with rank-dependent utility agents supports these predictions, as demonstrated in our extensive empirical study.
OPERATIONS RESEARCH
(2023)
Article
Physics, Fluids & Plasmas
Ping-Tong Qian, Xiao-Bo Zhang, Chen Jiao, Xiang-Yu Cui, Ai-Xia Zhang, Ju-Kui Xue
Summary: The interaction between an electromagnetic pulse and a relativistic hot plasma is studied analytically and numerically, revealing the transition from wakefield generation to soliton excitation. Nonlinear Schrodinger equations are derived and bright and dark soliton solutions are obtained. The stability phase diagram of solitons and modulation instability of plane waves are also studied. The results show that the wakefield-soliton transition depends on plasma density and thermal effects. This research provides theoretical evidence for understanding high-power laser plasma interactions.
PHYSICS OF PLASMAS
(2023)
Review
Energy & Fuels
Shuangxing Liu, Ming Xue, Xiangyu Cui, Wenzheng Peng
Summary: Due to its high energy density, potential reserves and clean combustion emissions, natural gas hydrate (NGH) is considered as a promising alternative to traditional fossil energy. However, methane emissions during NGH exploitation can significantly impact its environmental friendliness. This review discusses methane emission detection in three interfaces: seafloor and sediment, seawater, and atmosphere. Existing technologies can identify and quantify methane emissions, although their accuracy varies. Future research should focus on quantifying the environmental impact of methane emissions and predicting its diffusion in different environments.
FRONTIERS IN ENERGY RESEARCH
(2023)
Article
Optics
Hao Wu, Chunlei Jiang, Shaopeng Tian, Shangzhao Shao, Hangyu Yue, Xiangyu Cui, Bingkun Gao, Xiufang Wang, Peng Chen
Summary: This paper presents a multifunctional single-fiber optical tweezer for particle trapping and transport. By modifying the structure of the fiber probe and using laser sources with different wavelengths and modes, non-contact trapping and long-distance transport of particles can be achieved.
CHINESE OPTICS LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Dongju Li, Bingkun Gao, Xiangyu Cui
Summary: In this study, the main factors affecting the emulsifying stability of flowback fluids from acidizing oil wells in the DaQing oilfield of China were investigated using a high-speed emulsifier and electric dehydrator. The study explored the effects of various components on the emulsion stability, including inorganic salts, solid nanoparticles, polymers, and surfactants. The results showed that sodium chloride had the best ability to maintain the stability of the emulsion, and the effect of ferrous sulfide nanoparticles was higher than that of silica nanoparticles and calcium carbonate nanoparticles. The study also clarified the mechanism of multi-factor synergistic emulsification. These findings are of great significance to the efficient treatment of oilfield-produced fluids and environmental protection.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Xiaolai Zhang, Mingyue Fu, Hongyan Liu, Yutong Wang, Yecheng Zou, Li Wang, Chenhao Li, Yong Lu, Liangliang Zhou, Xiangyu Cui
Summary: In this study, a copper-based metal-organic framework (MOF) was synthesized to selectively adsorb acetylene over ethylene. Breakthrough experiments demonstrated that this MOF can effectively purify the acetylene/ethylene mixture, producing high-purity ethylene as the product.
INORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Multidisciplinary
Wafa A. Bawazir, Maymoona A. Al-Mahmood, Rawan S. Almalki, Ghadi F. Alofi, Raghad S. Alharbi, Zoya Zaheer
Summary: This study investigates the interaction between sulfathiazole and three types of surfactants using UV-visible spectroscopy and conductivity measurements. The results show that the critical micelle concentration of cationic and anionic surfactants decreases with increasing sulfathiazole concentration, while the interaction with non-ionic surfactant is weak.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Musaad K. Aleid, Khalid N. Alharbi, Mona A. Aljufareen, Areej S. Aloliwi, Alhanouf K. Almutairi, Rahaf S. Alsaif, Nada K. Alshayeb, Mohammed S. Almoiqli
Summary: This study assessed the levels of trihalomethane compounds in the water network of Riyadh city and identified the factors influencing their formation. The concentrations of trihalomethane compounds were within the permissible limits, indicating the water's safety for human consumption. The presence of bromide ions, organic carbon, free chlorine, and pH values were found to affect trihalomethane formation.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Said Arhzaf, Jamal Houssaini, Mohammed Naciri Bennani, Marwa Alaqarbeh, Mohammed Bouachrine
Summary: The study shows that Mg-Al hydrotalcite catalysts intercalated with acetate and carbonate anions exhibit superior catalytic activity in the aldol condensation reaction between furfural and acetone. The optimal reaction conditions are at 90 degrees C for 2 hours, achieving conversion rates of over 98% with high selectivity towards F2A for the acetate catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Uyen-Chi Nguyen Le, Ngoc Xuan Dat Mai, Kieu-Minh Le, Hoang Anh Vu, Huynh-Nhu Thi Tran, Tan Le Hoang Doan
Summary: This study aimed to enhance the bioavailability of rosmarinic acid, a bioactive compound with high anticancer activity, by encapsulating it in tetrasulfide-based porous organosilica nanoparticles. The synthesized nanoparticles were small in size and had a high surface area and an average pore diameter. The nanoparticles showed effective accumulation in cancer cells without toxicity to normal cells. Treatment with rosmarinic acid-containing nanoparticles resulted in significant cell death in cancer cells. Overall, these findings suggest that the synthesized nanoparticles can enhance the pharmacological effects of rosmarinic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jiamin Qi, Hengxi Zhu, Tianyu Yang, Xingyuan Wang, Zixuan Wang, Xiaoli Lei, Bin Li, Wenmin Qian
Summary: This study synthesized a novel iron-biochar adsorbent using the iron content in red mud to remove heavy metals from wastewater. The adsorbent showed excellent removal efficiency and sustainability. This method addresses both industrial waste recovery and heavy metal adsorption issues.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Bo Yi, Li Zhang, Haiyang Zhou
Summary: Plasma protein binding plays a crucial role in the pharmacokinetics and pharmacodynamics of therapeutic bioactive materials. In this study, the interaction of nordentatin, a member of coumarins, with human alpha-1 acid glycoprotein (AGP) was investigated, and the anticancer potency of nordentatin against human colorectal cancer cells was evaluated. The results showed that nordentatin binds to AGP through a static quenching mechanism and exhibits inhibitory effects on the growth of HCT-116 cells by increasing intracellular ROS and [Ca2+] levels and triggering apoptosis-related gene overexpression. Therefore, nordentatin could be a promising plant-based therapy for colorectal cancer.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qiming Pang, Cui Wang, Bangtao Li, Suli Zhang, Jiaoyang Li, Shuo Gu, Xueyu Shi
Summary: This study evaluated the effects of resveratrol loaded in copolymer nanoparticles on cerebral ischemia/reperfusion (I/R) injury in rats. The results showed that RES.CP.NPs could have neuroprotective effects through their antioxidant and anti-inflammatory activities, leading to improved neurological disability scores and decreased oxidative stress levels.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T. H. Wu, Hsu-Shan Huang
Summary: Tetraheterocyclic compounds derived from natural sources and contemporary pharmaceuticals have shown promise as multitarget therapeutic agents. In this study, a series of synthesized compounds were evaluated for their potential in breast cancer treatment. Compounds 18 and 20 demonstrated significant antiproliferative activity against breast cancer cell lines and their mode of action was revealed through molecular docking simulations.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mohammad Khosravani, Mohsen Dehghani Ghanatghestani, Farid Moeinpour, Hossein Parvaresh
Summary: The aim of removing Pb(II) from water is to minimize the potential harm posed by toxic metals to both human health and the environment. A covalent organic framework adsorbent called TFPOTDB-SO3H was developed with excellent properties such as high repeatability, selectivity, and easy solid-liquid separation. The adsorbent showed impressive capability of adsorbing Pb(II) and effective removal of it from a solution with various ions, suggesting its potential for effectively adsorbing and removing Pb(II) heavy metal ions from wastewater.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Ashraf H. Farha, Mohamed S. Shams, Hasna A. Alali, Zakia H. Alhashem, Shehab A. Mansour, Shrouq H. Aleithan, Ragab A. Elsad
Summary: The current study examines the dielectric and thermal properties of transformer oil incorporated with Mn0.5 Zn0.5 Fe2O4 nanoparticles. The results show that the addition of Mn-Zn ferrite NPs improves the dielectric constant, dissipation factor, AC breakdown voltage, and convective heat transfer of the nanofluid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Limin Hou, Zongpei Jiang, Minqi Ye, Xueyan Sun, Kexin Liu, Yifan Zhu, Xiaoyu Wang, Liangzhu Chen, Ruiheng Gu, Binghu Fang
Summary: The excessive accumulation of antibiotic residue in animal-derived foods poses a threat to health. Therefore, it is necessary to establish a rapid, simple, effective, safe, and highly sensitive method for detecting lincomycin residues. By using a pre-column derivatization method on high-performance liquid chromatography equipped with ultraviolet, the UV absorption of lincomycin is improved, allowing for detection and quantification.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Kun Tang, Xin-Xin Wang, Jin-Jin Zhao, Ning Ren, Jian-Jun Zhang
Summary: This study reports the synthesis, crystal structures, and thermal degradation properties of three new rare earth coordination compounds. Compounds 1-3 exhibit binuclear structures which can form chain-like structures via hydrogen bonding. Compound 2 shows potential application value in the orange-red luminescence region.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Seoyoun Yang, Eunbi Yu, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Su Bin Han, Soo Hyun Kang, Jung Hyun Lee, Heejun Ha, Minkyung Song, Jae Youl Cho, Jongsung Lee
Summary: This study investigated the effects of blue light on the hypodermis and found that it has antiadipogenic properties by reducing lipid accumulation and downregulating the expression of adipogenic genes. Blue light also increased the phosphorylation of PPAR gamma and TRPV1, suggesting its anti-adipogenic effect through these signaling pathways.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Abdul Nasir, Abdul Waheed Khan, Hamid Rafiq Khattak, Abdus Samad, Sami Ullah, Haroon Khan, Muhammad Faheem, Qian Bai
Summary: This study evaluated the effects of isoxazolone derivatives on cisplatin-induced neuropathy in a rat model. The results showed that isoxazolone derivatives effectively reversed mechanical allodynia, similar to the known therapeutic agent pregabalin. Molecular docking analysis indicated that isoxazolone derivatives have strong binding affinity for relevant receptors and potential inhibitory activity against relevant signaling pathways. This study has innovative implications for the treatment of cisplatin-induced neuropathic pain.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Shahid Wahab, Haroon Muhammad Ali, Maham Khan, Tariq Khan, Chandran Krishnaraj, Soon-Il Yun
Summary: In this study, we synthesized chitosan nanoparticles, silver nanoparticles, and chitosan/silver nanocomposites using aqueous ginger extract as a green approach. These nanomaterials showed significant antibacterial properties and low toxicity. Furthermore, the nanomaterials conjugated with tobramycin demonstrated enhanced antibacterial efficacy and exhibited interactions with Pseudomonas aeruginosa.
ARABIAN JOURNAL OF CHEMISTRY
(2024)