Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation

Lymphocytes and Trogocytosis-Mediated Signaling

(2021) Jim Reed et al.   Cells

Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics

(2020) Simon Zenke et al.   IMMUNITY

Biological functions and therapeutic opportunities of soluble cytokine receptors

(2020) Juliane Lokau et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Inducible Polarized Secretion of Exosomes in T and B Lymphocytes

(2020) Victor Calvo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

(2020) Georg Michlits et al.   NATURE METHODS

Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells

(2020) Candida Wong et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy

(2019) Yan Zhang et al.   CELL RESEARCH

CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides

(2019) Shu-Wei Wu et al.   Frontiers in Immunology

Life in the lumen: The multivesicular endosome

(2019) Jean Gruenberg   TRAFFIC

Induction of CD4 T cell memory by local cellular collectivity

(2018) Michal Polonsky et al.   SCIENCE

Inhibitory and Coactivating Receptors Recognising the Same Ligand: Immune Homeostasis Exploited by Pathogens and Tumours

(2018) Francesca Levi-Schaffer et al.   TRENDS IN IMMUNOLOGY

To degrade or not to degrade: mechanisms and significance of endocytic recycling

(2018) Peter J. Cullen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

(2018) Philippe E. Mangeot et al.   Nature Communications

IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8+ T cells

(2017) Lei Li et al.   Scientific Reports

Late Endosomal Recycling of Open MHC-I Conformers

(2016) Hana Mahmutefendić et al.   JOURNAL OF CELLULAR PHYSIOLOGY

mScarlet: a bright monomeric red fluorescent protein for cellular imaging

(2016) Daphne S Bindels et al.   NATURE METHODS

Immature dendritic cells convert anergic nonregulatory T cells into Foxp3−IL-10+regulatory T cells by engaging CD28 and CTLA-4

(2014) Katrien Pletinckx et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function

(2013) André Schönichen et al.   Annual Review of Biophysics

Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection

(2013) Noah J. Tubo et al.   CELL

Secondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cells

(2013) Audrey Gérard et al.   NATURE IMMUNOLOGY

Disparate Individual Fates Compose Robust CD8+ T Cell Immunity

(2013) V. R. Buchholz et al.   SCIENCE

Heterogeneous Differentiation Patterns of Individual CD8+ T Cells

(2013) C. Gerlach et al.   SCIENCE

Trogocytosis Results in Sustained Intracellular Signaling in CD4+ T Cells

(2012) D. G. Osborne et al.   JOURNAL OF IMMUNOLOGY

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Presentation of Acquired Peptide-MHC Class II Ligands by CD4+ Regulatory T Cells or Helper Cells Differentially Regulates Antigen-Specific CD4+ T Cell Response

(2011) G. Zhou et al.   JOURNAL OF IMMUNOLOGY

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Intercellular Trogocytosis Plays an Important Role in Modulation of Immune Responses

(2010) Khawaja Ashfaque Ahmed et al.   Cellular & Molecular Immunology

Mechanisms of cellular communication through intercellular protein transfer

(2010) Khawaja Ashfaque Ahmed et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates

(2010) Jochen S. Hub et al.   Journal of Chemical Theory and Computation

A Screen for Endocytic Motifs

(2010) Patrycja Kozik et al.   TRAFFIC

A Synaptic Basis for Paracrine Interleukin-2 Signaling during Homotypic T Cell Interaction

(2008) Catherine A. Sabatos et al.   IMMUNITY

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA