Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 44, Issue 5, Pages 1354-1359Publisher
WILEY
DOI: 10.1002/jmri.25284
Keywords
magnetic resonance imaging; prostate cancer; scoring method; validation studies
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PurposeTo date, few studies have validated the Prostate Imaging Reporting and Data System Version 2 (PI-RADS v. 2) for the diagnosis of prostate cancer. Our aim was to validate PI-RADS v.2 using 3 Tesla (T) MRI. Materials and MethodsThis is a retrospective study of 54 consecutive patients who underwent 3T MRI with a body-array coil for diagnostic confirmation of prostate cancer or cancer staging between June 2013 and June 2015. Sensitivity, specificity, and agreement were calculated based on a criterion of PI-RADS score = 3. Inter-examiner agreement was determined by the weighted kappa statistic. ResultsHistological findings were positive for cancer in 33 patients and negative in 21 patients. Considering a PI-RADS score of 3 as positive for cancer, the accuracy of each reader was 85.20% and 70.40%, respectively, and agreement coefficients were = 0.69 and = 0.35. Considering PI-RADS 3 as absence of cancer, the accuracy of each reader was 77.80% and 77.80%, respectively, and agreement was = 0.55 and = 0.54. Inter-reader agreement was moderate/good (weighted = 0.53; 95% confidence interval: 0.39-0.66; P=0.038). ConclusionHigh accuracy was obtained for the diagnosis of prostate cancer using 3T MRI with a body coil and the PI-RADS v.2 score. J. Magn. Reson. Imaging 2016;44:1354-1359.
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