MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T

Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations

(2015) U. E. Emir et al.   CANCER RESEARCH

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

(2015) Patrick J. Killela et al.   Oncotarget

Multicenter Study of Subjective Acceptance During Magnetic Resonance Imaging at 7 and 9.4 T

(2014) Jaane Rauschenberg et al.   INVESTIGATIVE RADIOLOGY

Distribution of immunoreactive glutamine synthetase in the adult human and mouse brain. Qualitative and quantitative observations with special emphasis on extra-astroglial protein localization

(2014) Hans-Gert Bernstein et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 tesla for characterization of differences in metabolite levels

(2014) Yan Li et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

In vivo proton magnetic resonance spectroscopic imaging of the healthy human brain at 9.4 T: initial experience

(2014) Grzegorz L. Chadzynski et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

A vaccine targeting mutant IDH1 induces antitumour immunity

(2014) Theresa Schumacher et al.   NATURE

Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation

(2014) Fumiharu Ohka et al.   TUMOR BIOLOGY

Multimodal Elucidation of Choline Metabolism in a Murine Glioma Model Using Magnetic Resonance Spectroscopy and 11C-Choline Positron Emission Tomography

(2013) H. F. Wehrl et al.   CANCER RESEARCH

A 16-channel dual-row transmit array in combination with a 31-element receive array for human brain imaging at 9.4 T

(2013) G. Shajan et al.   MAGNETIC RESONANCE IN MEDICINE

A comparative study of short- and long-TE1H MRS at 3 T forin vivodetection of 2-hydroxyglutarate in brain tumors

(2013) Changho Choi et al.   NMR IN BIOMEDICINE

Detection of “oncometabolite” 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma

(2012) Juliya Kalinina et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

(2012) Changho Choi et al.   NATURE MEDICINE

A theoretical and experimental comparison of different techniques forB1mapping at very high fields

(2012) Rolf Pohmann et al.   NMR IN BIOMEDICINE

Detection of 2-Hydroxyglutarate in IDH-Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy

(2012) O. C. Andronesi et al.   Science Translational Medicine

Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas

(2012) A. Elkhaled et al.   Science Translational Medicine

Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma

(2011) Jens Schittenhelm et al.   ACTA NEUROPATHOLOGICA

Clinical applications of 7T MRI in the brain

(2011) Anja G. van der Kolk et al.   EUROPEAN JOURNAL OF RADIOLOGY

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

(2011) Whitney B. Pope et al.   JOURNAL OF NEURO-ONCOLOGY

Role of very high order and degreeB0shimming for spectroscopic imaging of the human brain at 7 tesla

(2011) Jullie W. Pan et al.   MAGNETIC RESONANCE IN MEDICINE

High-resolution mapping of human brain metabolites by free induction decay 1H MRSI at 7 T

(2011) W. Bogner et al.   NMR IN BIOMEDICINE

Localized 1H NMR spectroscopy in different regions of human brain in vivo at 7 T: T2 relaxation times and concentrations of cerebral metabolites

(2011) Małgorzata Marjańska et al.   NMR IN BIOMEDICINE

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

(2011) Z. J. Reitman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurologic 3D MR Spectroscopic Imaging with Low-Power Adiabatic Pulses and Fast Spiral Acquisition

(2011) Ovidiu C. Andronesi et al.   RADIOLOGY

Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1

(2010) M. J. Seltzer et al.   CANCER RESEARCH

In vivo 1H NMR spectroscopy of the human brain at 9.4T: Initial results

(2010) Dinesh Kumar Deelchand et al.   JOURNAL OF MAGNETIC RESONANCE

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas

(2009) Christian Hartmann et al.   ACTA NEUROPATHOLOGICA

Characterization of R132H Mutation-specific IDH1 Antibody Binding in Brain Tumors

(2009) David Capper et al.   BRAIN PATHOLOGY

Novel Molecular Stereotactic Biopsy Procedures Reveal Intratumoral Homogeneity of Loss of Heterozygosity of 1p/19q and TP53 Mutations in World Health Organization Grade II Gliomas

(2009) Niklas Thon et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

In vivo1H NMR spectroscopy of the human brain at high magnetic fields: Metabolite quantification at 4T vs. 7T

(2009) Ivan Tkáč et al.   MAGNETIC RESONANCE IN MEDICINE

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Slice-selective FID acquisition, localized by outer volume suppression (FIDLOVS) for1H-MRSI of the human brain at 7 T with minimal signal loss

(2009) Anke Henning et al.   NMR IN BIOMEDICINE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE