The A to I editing landscape in melanoma and its relation to clinical outcome

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes

(2022) Görkem Garipler et al.   Cell Reports

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

(2021) Kevin Litchfield et al.   CELL

CDK4/6 Inhibitors in Melanoma: A Comprehensive Review

(2021) Mattia Garutti et al.   Cells

Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600–mutant melanoma

(2020) Paolo A. Ascierto et al.   EUROPEAN JOURNAL OF CANCER

Quantifying RNA Editing in Deep Transcriptome Datasets

(2020) Claudio Lo Giudice et al.   Frontiers in Genetics

Targeted Therapy in Melanoma and Mechanisms of Resistance

(2020) Anna M. Czarnecka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA binding RING E3-ligase DZIP3/hRUL138 stabilizes Cyclin D1 to drive cell cycle and cancer progression

(2020) Srinivasa P. Kolapalli et al.   CANCER RESEARCH

Overcoming Immune Evasion in Melanoma

(2020) Kevinn Eddy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted genomic profiling of acral melanoma

(2019) Iwei Yeh et al.   JNCI-Journal of the National Cancer Institute

Early Detection of Acral Melanoma: A Review of Clinical, Dermoscopic, Histopathologic, and Molecular Characteristics

(2019) Claudia C. Darmawan et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Many ways to resistance: How melanoma cells evade targeted therapies

(2019) Ines Kozar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

RNA Editing by ADAR Adenosine Deaminases: From Molecular Plasticity of Neural Proteins to the Mechanisms of Human Cancer

(2019) A. O. Goncharov et al.   BIOCHEMISTRY-MOSCOW

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

(2019) James P. Solomon et al.   MODERN PATHOLOGY

Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity

(2019) Shalom Hillel Roth et al.   NATURE METHODS

Principles of Targeted Therapy for Melanoma

(2019) James Sun et al.   SURGICAL CLINICS OF NORTH AMERICA

Primary and Metastatic Melanoma With NTRK Fusions

(2018) Cecilia Lezcano et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

OUP accepted manuscript

(2018)   BIOINFORMATICS

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression

(2018) Guermarie Velazquez-Torres et al.   Nature Communications

RNA editing derived epitopes function as cancer antigens to elicit immune responses

(2018) Minying Zhang et al.   Nature Communications

bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling

(2018) Fereshteh Haghighi et al.   Cell Communication and Signaling

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

(2018) Jeffrey J. Ishizuka et al.   NATURE

The Role of RNA Editing in Cancer Development and Metabolic Disorders

(2018) Che-Pei Kung et al.   Frontiers in Endocrinology

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer

(2016) Tim Hon Man Chan et al.   GASTROENTEROLOGY

ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma

(2016) Yuan-Bin Chen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

(2016) Kiranmai Gumireddy et al.   Nature Communications

Altered RNA editing in 3′ UTR perturbs microRNA-mediated regulation of oncogenes and tumor-suppressors

(2016) Liye Zhang et al.   Scientific Reports

RNA editing of non-coding RNA and its role in gene regulation

(2015) Chammiran Daniel et al.   BIOCHIMIE

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

A new live-cell biobank workflow efficiently recovers heterogeneous melanoma cells from native biopsies

(2015) Marieke I. G. Raaijmakers et al.   EXPERIMENTAL DERMATOLOGY

Novel CARM1-Interacting Protein, DZIP3, Is a Transcriptional Coactivator of Estrogen Receptor-α

(2015) Daniel J. Purcell et al.   MOLECULAR ENDOCRINOLOGY

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

(2015) Einav Shoshan et al.   NATURE CELL BIOLOGY

Activating MET kinase rearrangements in melanoma and Spitz tumours

(2015) Iwei Yeh et al.   Nature Communications

ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma

(2015) Katherine E. Hutchinson et al.   Oncotarget

Profiling RNA editing in human tissues: towards the inosinome Atlas

(2015) Ernesto Picardi et al.   Scientific Reports

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

RNA editing inRHOQpromotes invasion potential in colorectal cancer

(2014) Sae-Won Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma

(2014) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss ofCDKN2Aexpression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

(2014) Richard J. Young et al.   Pigment Cell & Melanoma Research

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

(2014) Thomas Wiesner et al.   Nature Communications

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

REDItools: high-throughput RNA editing detection made easy

(2013) Ernesto Picardi et al.   BIOINFORMATICS

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

(2013) Leilei Chen et al.   NATURE MEDICINE

Spontaneous Peripheral T-cell Responses toward the Tumor-Associated Antigen Cyclin D1 in Patients with Clear Cell Renal Cell Carcinoma

(2013) S. R. Dannenmann et al.   Cancer Immunology Research

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The BTB-ZF transcription factors

(2012) Owen Siggs et al.   CELL CYCLE

POK/ZBTB proteins: an emerging family of proteins that regulate lymphoid development and function

(2012) Sung-Uk Lee et al.   IMMUNOLOGICAL REVIEWS

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

(2012) Anirudh Prahallad et al.   NATURE

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib

(2012) Ryan B. Corcoran et al.   Cancer Discovery

The Promyelocytic Leukemia Zinc Finger Protein: Two Decades of Molecular Oncology

(2012) Bandar Ali Suliman et al.   Frontiers in Oncology

Overexpression of Renal Tumor Antigen Is Associated with Tumor Invasion and Poor Prognosis of Hepatocellular Carcinoma

(2011) Hyung Jin Cha et al.   ANNALS OF SURGICAL ONCOLOGY

The multiple roles of amphiregulin in human cancer

(2011) Benoit Busser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Functions and regulation of the APOBEC family of proteins

(2011) Harold C. Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1

(2010) J. Yeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome diversification by adenosine to inosine RNA-editing

(2010) Dieter Pullirsch et al.   RNA Biology

A Survey of Genomic Traces Reveals a Common Sequencing Error, RNA Editing, and DNA Editing

(2010) Alexander Wait Zaranek et al.   PLoS Genetics

Spitzoid melanoma

(2009) Hideko Kamino   CLINICS IN DERMATOLOGY

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

(2009) H. Wahlstedt et al.   GENOME RESEARCH

Amphiregulin Promotes BAX Inhibition and Resistance to Gefitinib in Non-small-cell Lung Cancers

(2009) Benoît Busser et al.   MOLECULAR THERAPY

The impact of retrotransposons on human genome evolution

(2009) Richard Cordaux et al.   NATURE REVIEWS GENETICS

Evidence for large diversity in the human transcriptome created by Alu RNA editing

(2009) Michal Barak et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE

Adenosine-to-inosine RNA editing

(2009) Boris Zinshteyn et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine