Development and Evaluation of Dissolving Microarray Patches for Co-administered and Repeated Intradermal Delivery of Long-acting Rilpivirine and Cabotegravir Nanosuspensions for Paediatric HIV Antiretroviral Therapy

Efficacy, Safety, and Durability of Long-Acting Cabotegravir and Rilpivirine in Adults With Human Immunodeficiency Virus Type 1 Infection: 5-Year Results From the LATTE-2 Study

(2021) Graham H R Smith et al.   Open Forum Infectious Diseases

Exploration into the opinions of patients with HIV, healthcare professionals and the lay public of the use of microneedles in clinical practice: highlighting the translational potential for their role in HIV infection

(2020) Kurtis Moffatt et al.   Drug Delivery and Translational Research

Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery

(2019) Maelíosa T. C. Mc Crudden et al.   Advanced Healthcare Materials

Modelling the intradermal delivery of microneedle array patches for long-acting antiretrovirals using PBPK

(2019) Rajith K.R. Rajoli et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Solid lipid nanoparticle-based dissolving microneedles: A promising intradermal lymph targeting drug delivery system with potential for enhanced treatment of lymphatic filariasis

(2019) Andi Dian Permana et al.   JOURNAL OF CONTROLLED RELEASE

Budesonide nanocrystal-loaded hyaluronic acid microparticles for inhalation: In vitro and in vivo evaluation

(2018) Tingting Liu et al.   CARBOHYDRATE POLYMERS

Microarray patches: potentially useful delivery systems for long-acting nanosuspensions

(2018) Ryan F. Donnelly et al.   DRUG DISCOVERY TODAY

Rilpivirine long-acting for the prevention and treatment of HIV infection

(2018) Francesca Ferretti et al.   Current Opinion in HIV and AIDS

Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension

(2018) Maelíosa T.C. Mc Crudden et al.   JOURNAL OF CONTROLLED RELEASE

Successful application of large microneedle patches by human volunteers

(2017) Anastasia Ripolin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Multimodal imaging approach to examine biodistribution kinetics of Cabotegravir (GSK1265744) long acting parenteral formulation in rat

(2017) Beat M. Jucker et al.   JOURNAL OF CONTROLLED RELEASE

Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis

(2017) Patricia González-Vázquez et al.   JOURNAL OF CONTROLLED RELEASE

Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial

(2017) David A Margolis et al.   LANCET

Formulation and pharmacology of long-acting rilpivirine

(2015) Peter E. Williams et al.   Current Opinion in HIV and AIDS

Formulation and pharmacology of long-acting cabotegravir

(2015) Christine Trezza et al.   Current Opinion in HIV and AIDS

A proposed model membrane and test method for microneedle insertion studies

(2014) Eneko Larrañeta et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Pharmacokinetics, Safety, and Tolerability With Repeat Doses of GSK1265744 and Rilpivirine (TMC278) Long-Acting Nanosuspensions in Healthy Adults

(2014) William Spreen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

GSK1265744 Pharmacokinetics in Plasma and Tissue After Single-Dose Long-Acting Injectable Administration in Healthy Subjects

(2014) William Spreen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Hydrogel-Forming Microneedle Arrays Can Be Effectively Inserted in Skin by Self-Application: A Pilot Study Centred on Pharmacist Intervention and a Patient Information Leaflet

(2014) Ryan F. Donnelly et al.   PHARMACEUTICAL RESEARCH

Long-Term Reduction in Poly(dimethylsiloxane) Surface Hydrophobicity via Cold-Plasma Treatments

(2013) B. J. Larson et al.   LANGMUIR

Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada

(2013) Hasina Samji et al.   PLoS One

Adherence as a Predictor of the Development of Class-Specific Resistance Mutations: The Swiss HIV Cohort Study

(2013) Viktor von Wyl et al.   PLoS One

Patterns of antiretroviral therapy adherence and impact on HIV RNA among patients in North America

(2012) Becky L. Genberg et al.   AIDS

Rilpivirine: a new non-nucleoside reverse transcriptase inhibitor

(2012) M. Sharma et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

What Will It Take to Eliminate Pediatric HIV? Reaching WHO Target Rates of Mother-to-Child HIV Transmission in Zimbabwe: A Model-Based Analysis

(2012) Andrea L. Ciaranello et al.   PLOS MEDICINE

Pharmacokinetics and Disposition of Rilpivirine (TMC278) Nanosuspension as a Long-Acting Injectable Antiretroviral Formulation

(2010) G. van 't Klooster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design, Optimization and Characterisation of Polymeric Microneedle Arrays Prepared by a Novel Laser-Based Micromoulding Technique

(2010) Ryan F. Donnelly et al.   PHARMACEUTICAL RESEARCH

The Combined Effect of Modern Highly Active Antiretroviral Therapy Regimens and Adherence on Mortality Over Time

(2009) Viviane D Lima et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Development of an oral rutin nanocrystal formulation

(2008) Rachmat Mauludin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS