Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes

Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease

(2016) A.-M. K. Jepsen et al.   CLINICAL CHEMISTRY

Role of lipoprotein lipase in lipid metabolism

(2016) Gunilla Olivecrona   CURRENT OPINION IN LIPIDOLOGY

Regulation of lipid metabolism by angiopoietin-like proteins

(2016) Wieneke Dijk et al.   CURRENT OPINION IN LIPIDOLOGY

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

(2016) Philip L.S.M. Gordts et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency

(2016) Rute Rodrigues et al.   Journal of Clinical Lipidology

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

(2016) Wieneke Dijk et al.   JOURNAL OF LIPID RESEARCH

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease

(2016) Anna Helgadottir et al.   NATURE GENETICS

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

(2016) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking

(2016) Ren Zhang   Open Biology

JCL Roundtable: Hypertriglyceridemia due to defects in lipoprotein lipase function

(2015) W. Virgil Brown et al.   Journal of Clinical Lipidology

Chylomicronaemia—current diagnosis and future therapies

(2015) Amanda J. Brahm et al.   Nature Reviews Endocrinology

Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia

(2015) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apolipoprotein C-III: From Pathophysiology to Pharmacology

(2015) Giuseppe Danilo Norata et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

(2014) Gina M. Peloso et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physiological regulation of lipoprotein lipase

(2014) Sander Kersten   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Apolipoprotein E isoforms and lipoprotein metabolism

(2014) Michael C. Phillips   IUBMB LIFE

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

(2014) Ron Do et al.   NATURE

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

(2014) Anders Berg Jørgensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting APOC3 in the Familial Chylomicronemia Syndrome

(2014) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of lipoprotein lipase by Angptl4

(2014) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Biochemistry and pathophysiology of intravascular and intracellular lipolysis

(2013) S. G. Young et al.   GENES & DEVELOPMENT

Apolipoproteins C-I and C-III Inhibit Lipoprotein Lipase Activity by Displacement of the Enzyme from Lipid Droplets

(2013) Mikael Larsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 and the intravascular processing of triglyceride-rich lipoproteins

(2013) O. Adeyo et al.   JOURNAL OF INTERNAL MEDICINE

Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis

(2013) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein C-III and hepatic triglyceride-rich lipoprotein production

(2012) Zemin Yao et al.   CURRENT OPINION IN LIPIDOLOGY

A review of the role of apolipoprotein C-II in lipoprotein metabolism and cardiovascular disease

(2012) Anastazia A. Kei et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Lipase maturation factor 1: A lipase chaperone involved in lipid metabolism

(2011) Miklós Péterfy   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Excess of Rare Variants in Non–Genome-Wide Association Study Candidate Genes in Patients With Hypertriglyceridemia

(2011) Christopher T. Johansen et al.   Circulation-Cardiovascular Genetics

GPIHBP1, an endothelial cell transporter for lipoprotein lipase

(2011) Stephen G. Young et al.   JOURNAL OF LIPID RESEARCH

Lipase maturation factor 1: structure and role in lipase folding and assembly

(2010) Mark H Doolittle et al.   CURRENT OPINION IN LIPIDOLOGY

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

(2010)   LANCET

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

(2010) Christopher T Johansen et al.   NATURE GENETICS

Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia

(2010) Kiran Musunuru et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipoprotein lipase: from gene to obesity

(2009) Hong Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia

(2009) Robert A. Hegele et al.   HUMAN MOLECULAR GENETICS

APOC1T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians

(2009) Piya Lahiry et al.   JOURNAL OF LIPID RESEARCH

Plasma lipoproteins: genetic influences and clinical implications

(2009) Robert A. Hegele   NATURE REVIEWS GENETICS

Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis

(2008) G. S. Sagoo et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

ANGPTL4 E40K and T266M

(2008) Philippa J. Talmud et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency

(2008) Gery Gerritsen et al.   JOURNAL OF LIPID RESEARCH

A Null Mutation in Human APOC3 Confers a Favorable Plasma Lipid Profile and Apparent Cardioprotection

(2008) T. I. Pollin et al.   SCIENCE