High-mobility group box protein 1 promotes the survival of myeloid-derived suppressor cells by inducing autophagy

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

(2015) Sujuan Guo et al.   Autophagy

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

(2015) Xue Yang et al.   Cell and Bioscience

Tumor-induced myeloid dysfunction and its implications for cancer immunotherapy

(2014) Michelle N. Messmer et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells

(2014) K. H. Parker et al.   CANCER RESEARCH

The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

(2014) Paul T. Thevenot et al.   IMMUNITY

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R–mediated apoptosis

(2014) Thomas Condamine et al.   JOURNAL OF CLINICAL INVESTIGATION

Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells

(2013) Kristine Porter et al.   Autophagy

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

(2013) Jeremy D. Waight et al.   JOURNAL OF CLINICAL INVESTIGATION

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Regulating the suppressors: apoptosis and inflammation govern the survival of tumor-induced myeloid-derived suppressor cells (MDSC)

(2012) Suzanne Ostrand-Rosenberg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Aptamer-Mediated Blockade of IL4R  Triggers Apoptosis of MDSCs and Limits Tumor Progression

(2012) F. Roth et al.   CANCER RESEARCH

Molecular Pathways: Tumor-Infiltrating Myeloid Cells and Reactive Oxygen Species in Regulation of Tumor Microenvironment

(2012) T. Lu et al.   CLINICAL CANCER RESEARCH

Interactions between autophagic and endo-lysosomal markers in endothelial cells

(2012) Clara L. Oeste et al.   HISTOCHEMISTRY AND CELL BIOLOGY

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

TNF signaling drives myeloid-derived suppressor cell accumulation

(2012) Xueqiang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress

(2011) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL

(2011) P. Sinha et al.   BLOOD

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

(2011) Tangying Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in cancer associated fibroblasts promotes tumor cell survival

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteomic Pathway Analysis Reveals Inflammation Increases Myeloid-Derived Suppressor Cell Resistance to Apoptosis

(2010) Olesya Chornoguz et al.   MOLECULAR & CELLULAR PROTEOMICS

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

(2010) D Tang et al.   ONCOGENE

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL