Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade

Do endogenous opioids mediate or fine-tune human pain relief?

(2021) Marie Eikemo et al.   PAIN

Occupancy of the kappa opioid receptor by naltrexone predicts reduction in drinking and craving

(2020) Bart de Laat et al.   MOLECULAR PSYCHIATRY

Blocking mu-opioid receptors inhibits social bonding in rituals

(2020) S. J. Charles et al.   Biology Letters

Development and in vivo evaluation of a novel kappa opioid receptor agonist as PET radiotracer with superior imaging characteristics

(2019) Songye Li et al.   JOURNAL OF NUCLEAR MEDICINE

Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects

(2019) Jarkko Johansson et al.   NEUROPSYCHOPHARMACOLOGY

Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study

(2019) Diana Martinez et al.   NEUROPSYCHOPHARMACOLOGY

Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

(2018) Kelly A Berg et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Opioid-independent and opioid-mediated modes of pain modulation

(2018) Chantal Berna et al.   JOURNAL OF NEUROSCIENCE

Hedonic processing in humans is mediated by an opioidergic mechanism in a mesocorticolimbic system

(2018) Christian Buchel et al.   eLife

Machine Learning Will Change Medicine

(2017) Michael Forsting   JOURNAL OF NUCLEAR MEDICINE

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Naltrexone increases negatively-valenced facial responses to happy faces in female participants

(2016) Isabell M. Meier et al.   PSYCHONEUROENDOCRINOLOGY

Sweet taste pleasantness is modulated by morphine and naltrexone

(2016) Marie Eikemo et al.   PSYCHOPHARMACOLOGY

A Toolbox for Nonlinear Regression inR: The Packagenlstools

(2015) Florent Baty et al.   Journal of Statistical Software

Endogenous Opioid Antagonism in Physiological Experimental Pain Models: A Systematic Review

(2015) Mads U. Werner et al.   PLoS One

Kinetic Modeling of 11C-LY2795050, A Novel Antagonist Radiotracer for PET Imaging of the Kappa Opioid Receptor in Humans

(2014) Mika Naganawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evaluation of the agonist PET radioligand [11C]GR103545 to image kappa opioid receptor in humans: Kinetic model selection, test–retest reproducibility and receptor occupancy by the antagonist PF-04455242

(2014) Mika Naganawa et al.   NEUROIMAGE

State-dependent μ-opioid modulation of social motivation

(2014) Guro E. Loseth et al.   Frontiers in Behavioral Neuroscience

Synthesis and Evaluation of 11C-LY2795050 as a  -Opioid Receptor Antagonist Radiotracer for PET Imaging

(2013) M.-Q. Zheng et al.   JOURNAL OF NUCLEAR MEDICINE

The brain opioid theory of social attachment: a review of the evidence

(2011) A.J. Machin et al.   BEHAVIOUR

Pharmacological differentiation of opioid receptor antagonists by molecular and functional imaging of target occupancy and food reward-related brain activation in humans

(2011) E A Rabiner et al.   MOLECULAR PSYCHIATRY

Evaluation of the kappa-opioid receptor-selective tracer [11C]GR103545 in awake rhesus macaques

(2010) Bent W. Schoultz et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Sex Differences in Pharmacokinetics and Pharmacodynamics

(2009) Offie P. Soldin et al.   CLINICAL PHARMACOKINETICS

Activation of the Opioidergic Descending Pain Control System Underlies Placebo Analgesia

(2009) Falk Eippert et al.   NEURON