Inferring and perturbing cell fate regulomes in human brain organoids
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inferring and perturbing cell fate regulomes in human brain organoids
Authors
Keywords
-
Journal
NATURE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-10-06
DOI
10.1038/s41586-022-05279-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CellRank for directed single-cell fate mapping
- (2022) Marius Lange et al. NATURE METHODS
- Mapping the molecular and cellular complexity of cortical malformations
- (2021) Esther Klingler et al. SCIENCE
- Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases
- (2021) Jonas Simon Fleck et al. Cell Stem Cell
- A Non-coding HES1 Variant Predisposes Children to Congenital Heart Disease in Chinese Population
- (2021) Yangliu Song et al. Frontiers in Cell and Developmental Biology
- A single-embryo, single-cell time-resolved model for mouse gastrulation
- (2021) Markus Mittnenzweig et al. CELL
- Molecular architecture of the developing mouse brain
- (2021) Gioele La Manno et al. NATURE
- Single-cell chromatin state analysis with Signac
- (2021) Tim Stuart et al. NATURE METHODS
- HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly
- (2021) Deepika Sharma et al. PLoS Genetics
- Chromatin accessibility dynamics in a model of human forebrain development
- (2020) Alexandro E. Trevino et al. SCIENCE
- Expanded encyclopaedias of DNA elements in the human and mouse genomes
- (2020) Jill E. Moore et al. NATURE
- Generalizing RNA velocity to transient cell states through dynamical modeling
- (2020) Volker Bergen et al. NATURE BIOTECHNOLOGY
- A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye and inhibitor-resistant high-fidelity DNA polymerase
- (2020) Janne Purhonen et al. NUCLEIC ACIDS RESEARCH
- SCIM: universal single-cell matching with unpaired feature sets
- (2020) Stefan G Stark et al. BIOINFORMATICS
- In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
- (2020) Xin Jin et al. SCIENCE
- Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia
- (2019) Johannes Klaus et al. NATURE MEDICINE
- Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
- (2019) Alex A. Pollen et al. CELL
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- CUT&Tag for efficient epigenomic profiling of small samples and single cells
- (2019) Hatice S. Kaya-Okur et al. Nature Communications
- Simultaneous precise editing of multiple genes in human cells
- (2019) Stephan Riesenberg et al. NUCLEIC ACIDS RESEARCH
- Organoid single-cell genomic atlas uncovers human-specific features of brain development
- (2019) Sabina Kanton et al. NATURE
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- On the design of CRISPR-based single-cell molecular screens
- (2018) Andrew J Hill et al. NATURE METHODS
- Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells
- (2018) Stephan Riesenberg et al. Nature Communications
- Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle throughCdk6expression
- (2018) Kerstin Hasenpusch-Theil et al. DEVELOPMENT
- RNA velocity of single cells
- (2018) Gioele La Manno et al. NATURE
- AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors
- (2018) Hui Hu et al. NUCLEIC ACIDS RESEARCH
- brms: An R Package for Bayesian Multilevel Models Using Stan
- (2017) Paul-Christian Bürkner Journal of Statistical Software
- Common genetic variation drives molecular heterogeneity in human iPSCs
- (2017) Helena Kilpinen et al. NATURE
- Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
- (2017) Hyun Min Kang et al. NATURE BIOTECHNOLOGY
- chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
- (2017) Alicia N Schep et al. NATURE METHODS
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- Pooled CRISPR screening with single-cell transcriptome readout
- (2017) Paul Datlinger et al. NATURE METHODS
- The use of brain organoids to investigate neural development and disease
- (2017) Elizabeth Di Lullo et al. NATURE REVIEWS NEUROSCIENCE
- Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex
- (2017) Tomasz J. Nowakowski et al. SCIENCE
- Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq
- (2016) Diego Adhemar Jaitin et al. CELL
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- Analyzing CRISPR genome-editing experiments with CRISPResso
- (2016) Luca Pinello et al. NATURE BIOTECHNOLOGY
- Near-optimal probabilistic RNA-seq quantification
- (2016) Nicolas L Bray et al. NATURE BIOTECHNOLOGY
- Single-cell analysis delineates a trajectory toward the human early otic lineage
- (2016) Megan Ealy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
- (2015) J. Gray Camp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity
- (2014) Matthew T. Weirauch et al. CELL
- An iCRISPR Platform for Rapid, Multiplexable, and Inducible Genome Editing in Human Pluripotent Stem Cells
- (2014) Federico González et al. Cell Stem Cell
- leeHom: adaptor trimming and merging for Illumina sequencing reads
- (2014) Gabriel Renaud et al. NUCLEIC ACIDS RESEARCH
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Modeling human cortical development in vitro using induced pluripotent stem cells
- (2012) J. Mariani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gli3 Is Required for Maintenance and Fate Specification of Cortical Progenitors
- (2011) H. Wang et al. JOURNAL OF NEUROSCIENCE
- Sonic hedgehog functions through dynamic changes in temporal competence in the developing forebrain
- (2010) Vitor H Sousa et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- GREAT improves functional interpretation of cis-regulatory regions
- (2010) Cory Y McLean et al. NATURE BIOTECHNOLOGY
- Biopython: freely available Python tools for computational molecular biology and bioinformatics
- (2009) P. J. A. Cock et al. BIOINFORMATICS
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- Fast unfolding of communities in large networks
- (2008) Vincent D Blondel et al. JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT
- The Greig cephalopolysyndactyly syndrome
- (2008) Leslie G Biesecker Orphanet Journal of Rare Diseases
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now