The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents

An Update on Synthesis of Coumarin Sulfonamides as Enzyme Inhibitors and Anticancer Agents

(2022) Laila Rubab et al.   MOLECULES

Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity

(2020) Junyu Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antibacterial activities with the structure-activity relationship of coumarin derivatives

(2020) Hua-Li Qin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A review: Biologically active 3,4-heterocycle-fused coumarins

(2020) Fatemeh Salehian et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Coumarin Hybrids: Promising Scaffolds in the Treatment of Breast Cancer

(2019) Rohit Bhatia et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Aloe emodin induces hepatotoxicity by activating NF-κB inflammatory pathway and P53 apoptosis pathway in zebrafish

(2019) Yunyun Quan et al.   TOXICOLOGY LETTERS

Coumarin-containing hybrids and their anticancer activities

(2019) Longfei Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, cytotoxicity and mechanism of novel dihydroartemisinin-coumarin hybrids as potential anti-cancer agents

(2018) Haonan Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aloe-emodin ameliorates renal fibrosis via inhibiting PI3K/Akt/mTOR signaling pathway in vivo and in vitro

(2018) Fang Dou et al.   REJUVENATION RESEARCH

Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells

(2018) Chunsheng Cheng et al.   MEDICAL SCIENCE MONITOR

Current developments of coumarin-based anti-cancer agents in medicinal chemistry

(2015) Saeed Emami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

(2015) Anuradha Thakur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aloe-emodin exerts a potent anticancer and immunomodulatory activity on BRAF-mutated human melanoma cells

(2015) Claudio Tabolacci et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Coumarin hybrids as novel therapeutic agents

(2014) Sonali Sandhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antiviral activity of aloe-emodin against influenza A virus via galectin-3 up-regulation

(2014) Shih-Wen Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Aloe-emodin from rhubarb (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages

(2014) Boyang Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB

(2011) Priya Suboj et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents

(2010) Federica Belluti et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient Synthesis of 1-Sulfonyl-1,2,3-triazoles

(2010) Jessica Raushel et al.   ORGANIC LETTERS

Evaluation of Aloin and Aloe-Emodin as Anti-Inflammatory Agents in Aloe by Using Murine Macrophages

(2009) Mi-Young PARK et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

(2009) Meng-Liang Lin et al.   CANCER LETTERS

Preparation of 1,8-Di-O-alkylaloe-emodins and 15-Amino-, 15-Thiocyano-, and 15-Selenocyanochrysophanol Derivatives from Aloe-Emodin and Studying Their Cytotoxic Effects

(2008) Xing-Ri Cui et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer

(2008) Musiliyu Musa et al.   CURRENT MEDICINAL CHEMISTRY