Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells

Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity

(2022) Alexander Panossian et al.   Pharmaceuticals

Network pharmacology of triptolide in cancer cells: implications for transcription factor binding

(2021) Ean-Jeong Seo et al.   INVESTIGATIONAL NEW DRUGS

Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells

(2021) Joelle C. Boulos et al.   Pharmaceuticals

Biological Activities of Gedunin—A Limonoid from the Meliaceae Family

(2020) Teresa M. Braga et al.   MOLECULES

Gedunin isolated from the mangrove plant Xylocarpus granatum exerts its anti-proliferative activity in ovarian cancer cells through G2/M-phase arrest and oxidative stress-mediated intrinsic apoptosis

(2020) Rohit Sahai et al.   APOPTOSIS

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells

(2020) Nadire Özenver et al.   MOLECULES

Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance

(2020) Nuray Erin et al.   DRUG RESISTANCE UPDATES

Identification of proteasome inhibitors using analysis of gene expression profiles

(2020) Arjan Mofers et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action

(2020) Mohamed-Elamir F. Hegazy et al.   PHYTOMEDICINE

Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells

(2020) Aveen N. Adham et al.   PHYTOMEDICINE

The emergence of drug resistance to targeted therapies: Clinical evidence

(2019) Ana Bela Sarmento-Ribeiro et al.   DRUG RESISTANCE UPDATES

DARK Classics in Chemical Neuroscience: Morphine

(2018) Andrea L. Devereaux et al.   ACS Chemical Neuroscience

Molecular bases of the poor response of liver cancer to chemotherapy

(2018) Jose J.G. Marin et al.   Clinics and Research in Hepatology and Gastroenterology

3D Models of the NCI60 Cell Lines for Screening Oncology Compounds

(2017) Mike Selby et al.   SLAS Discovery

The role of p53 in cancer drug resistance and targeted chemotherapy

(2016) Karin Hientz et al.   Oncotarget

Discovery and resupply of pharmacologically active plant-derived natural products: A review

(2015) Atanas G. Atanasov et al.   BIOTECHNOLOGY ADVANCES

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps

(2015) Tiannan Guo et al.   NATURE MEDICINE

Prediction of Cancer Drug Resistance and Implications for Personalized Medicine

(2015) Manfred Volm et al.   Frontiers in Oncology

Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis

(2013) Chaitanya A. Patwardhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Relevance of Higher Plants in Lead Compound Discovery Programs

(2011) A. Douglas Kinghorn et al.   JOURNAL OF NATURAL PRODUCTS

Complex Interactions between Phytochemicals. The Multi-Target Therapeutic Concept of Phytotherapy

(2010) Thomas Efferth et al.   CURRENT DRUG TARGETS

A Comparison of Hierarchical Methods for Clustering Functional Data

(2009) Laura Ferreira et al.   COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION

Prediction of Broad Spectrum Resistance of Tumors towards Anticancer Drugs

(2008) T. Efferth et al.   CLINICAL CANCER RESEARCH

Phytochemistry and pharmacogenomics of natural products derived from traditional chinese medicine and chinese materia medica with activity against tumor cells

(2008) T. Efferth et al.   MOLECULAR CANCER THERAPEUTICS