Efficacy of 2-Hydroxyflavanone in Rodent Models of Pain and Inflammation: Involvement of Opioidergic and GABAergic Anti-Nociceptive Mechanisms

ROS-Generating Amine-Functionalized Magnetic Nanoparticles Coupled with Carboxymethyl Chitosan for pH-Responsive Release of Doxorubicin

(2022) Sreekanth Reddy Obireddy et al.   International Journal of Nanomedicine

A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from Xylopia vielana Targeting B-Raf Kinase

(2022) Syed Shams ul Hassan et al.   MOLECULES

An Extensive Pharmacological Evaluation of New Anti-Cancer Triterpenoid (Nummularic Acid) from Ipomoea batatas through In Vitro, In Silico, and In Vivo Studies

(2022) Muhammad Majid et al.   MOLECULES

Piezoelectric ultrasound energy–harvesting device for deep brain stimulation and analgesia applications

(2022) Tao Zhang et al.   Science Advances

Underlying Anticancer Mechanisms and Synergistic Combinations of Phytochemicals with Cancer Chemotherapeutics: Potential Benefits and Risks

(2022) Muhammad Ayaz et al.   JOURNAL OF FOOD QUALITY

Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies

(2022) Fawad Mahmood et al.   MOLECULES

Transcranial Focused Ultrasound Stimulation of Periaqueductal Gray for Analgesia

(2022) Tao Zhang et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Neuroprotective potential of Malva neglecta is mediated via down-regulation of cholinesterase and modulation of oxidative stress markers

(2021) Uzma Saleem et al.   METABOLIC BRAIN DISEASE

Development of Hydrogels with Self-Healing Properties for Delivery of Bioactive Agents

(2021) Wing-Fu Lai   MOLECULAR PHARMACEUTICS

Core-shell chitosan microsphere with antimicrobial and vascularized functions for promoting skin wound healing

(2021) Hao Li et al.   MATERIALS & DESIGN

Computational Exploration of Anti-Cancer Potential of GUAIANE Dimers from Xylopia vielana by Targeting B-Raf Kinase Using Chemo-Informatics, Molecular Docking, and MD Simulation Studies

(2021) Syed Shams ul Hassan et al.   Anti-Cancer Agents in Medicinal Chemistry

Stress Driven Discovery of Natural Products From Actinobacteria with Anti-Oxidant and Cytotoxic Activities Including Docking and ADMET Properties

(2021) Syed Shams ul Hassan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Guaiane-type sesquiterpenoids from Cinnamomum migao H. W. Li: And their anti-inflammatory activities

(2021) Ishaq Muhammad et al.   PHYTOCHEMISTRY

6-Methoxyflavanone abates cisplatin-induced neuropathic pain apropos anti-inflammatory mechanisms: A behavioral and molecular simulation study

(2020) Shehla Akbar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An overview of the mechanisms of marine fungi-derived antiinflammatory and anti-tumor agents and their novel role in drug targeting

(2020) Syed Shams ul Hassan et al.   CURRENT PHARMACEUTICAL DESIGN

Floral extracts-mediated green synthesis of NiO nanoparticles and their diverse pharmacological evaluations

(2020) Ayesha Sani et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

In-silico anti-inflammatory potential of guaiane dimers from Xylopia vielana targeting COX-2

(2020) Syed Shams ul Hassan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Phytochemical study of Ligularia subspicata and valuation of its anti-inflammatory activity

(2020) Ishaq Muhammad et al.   FITOTERAPIA

Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative review

(2020) Zahra Memariani et al.   PHARMACOLOGICAL RESEARCH

Lawsonia Inermis Markedly Improves Cognitive Functions in Animal Models and Modulate Oxidative Stress Markers in the Brain

(2019) Numra Tariq Mir et al.   Medicina-Lithuania

Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders

(2019) Muhammad Ayaz et al.   Frontiers in Aging Neuroscience

One new sesquiterpene and one new iridoid derivative from Valeriana amurensis

(2019) Yang-Guo Xie et al.   Phytochemistry Letters

In Silico, Cytotoxic and Antioxidant Potential of Novel Ester, 3-hydroxyoctyl -5- trans-docosenoate Isolated from Anchusa arvensis (L.) M.Bieb. Against HepG-2 Cancer Cells

(2019) Sajid Hussain et al.   Drug Design Development and Therapy

Ipomoea batatas L. Lam. ameliorates acute and chronic inflammations by suppressing inflammatory mediators, a comprehensive exploration using in vitro and in vivo models

(2018) Muhammad Majid et al.   BMC Complementary and Alternative Medicine

Anti-Alzheimer’s Studies on β-Sitosterol Isolated from Polygonum hydropiper L.

(2017) Muhammad Ayaz et al.   Frontiers in Pharmacology

6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain

(2016) Shehla Akbar et al.   BIOMEDICINE & PHARMACOTHERAPY

Topical gabapentin gel alleviates allodynia and hyperalgesia in the chronic sciatic nerve constriction injury neuropathic pain model

(2016) M. Shahid et al.   EUROPEAN JOURNAL OF PAIN

2′-Hydroxy flavanone derivatives as an inhibitors of pro-inflammatory mediators: Experimental and molecular docking studies

(2015) Neeraj K. Patel et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Gender differences in a mouse model of chemotherapy-induced neuropathic pain

(2015) H Naji-Esfahani et al.   LABORATORY ANIMALS

Gabapentin, a Synthetic Analogue of Gamma Aminobutyric Acid, Reverses Systemic Acute Inflammation and Oxidative Stress in Mice

(2014) Jordana Maia Dias et al.   INFLAMMATION

Challenges in Analgesic Drug Development

(2009) D J Hewitt et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effect of Mexiletine on Dynamic Allodynia Induced by Chronic Constriction Injury of the Sciatic Nerve in Rats

(2009) Etsuko NAKAZATO-IMASATO et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Efflux of a suppressive neurotransmitter, GABA, across the blood-brain barrier

(2003) Atsuyuki Kakee et al.   JOURNAL OF NEUROCHEMISTRY