Inhibition of Radix Scutellariae flavones on carboxylesterase mediated activations of prodrugs

Rapid bioluminescence assay for monitoring rat CES1 activity and its alteration by traditional Chinese medicines

(2020) Jun Zhang et al.   Journal of Pharmaceutical Analysis

Impact of the Chinese herbal medicines on dual antiplatelet therapy with clopidogrel and aspirin: Pharmacokinetics and pharmacodynamics outcomes and related mechanisms in rats

(2019) Min Xiao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations

(2019) Sha-Sha Song et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Inhibition of human carboxylesterases by ginsenosides: structure–activity relationships and inhibitory mechanism

(2019) Zhao-Hui Sun et al.   Chinese Medicine

Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2

(2018) Zi-Miao Weng et al.   BIOORGANIC CHEMISTRY

The Impact of Carboxylesterases in Drug Metabolism and Pharmacokinetics

(2018) Li Di   CURRENT DRUG METABOLISM

Nevadensin is a naturally occurring selective inhibitor of human carboxylesterase 1

(2018) Ya-Qiao Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway

(2018) Jianzhuang Yao et al.   MOLECULAR PHARMACEUTICS

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

(2018) Sara E. Kearney et al.   ACS Central Science

Computational protein–ligand docking and virtual drug screening with the AutoDock suite

(2016) Stefano Forli et al.   Nature Protocols

A Two-Photon Ratiometric Fluorescent Probe for Imaging Carboxylesterase 2 in Living Cells and Tissues

(2015) Qiang Jin et al.   ACS Applied Materials & Interfaces

The Role of Human Carboxylesterases in Drug Metabolism: Have We Overlooked Their Importance?

(2013) S. Casey Laizure et al.   PHARMACOTHERAPY

Involvement of Carboxylesterase in Hydrolysis of Propranolol Prodrug during Permeation across Rat Skin

(2013) Teruko Imai et al.   Pharmaceutics

Carboxylesterase 1 (CES1) genetic polymorphisms and oseltamivir activation

(2012) Hao-Jie Zhu et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones

(2011) Chenrui Li et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Involvement of Carboxylesterase 1 and 2 in the Hydrolysis of Mycophenolate Mofetil

(2010) N. Fujiyama et al.   DRUG METABOLISM AND DISPOSITION

Nuclear receptor-mediated regulation of carboxylesterase expression and activity

(2010) Jeff L Staudinger et al.   Expert Opinion on Drug Metabolism & Toxicology

Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product

(2010) Chenrui Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins

(2010) Roger S. Holmes et al.   MAMMALIAN GENOME

Carboxylesterases: Structure, Function and Polymorphism

(2009) Tetsuo Satoh et al.   Biomolecules & Therapeutics

Metabolism and Disposition of the Thienopyridine Antiplatelet Drugs Ticlopidine, Clopidogrel, and Prasugrel in Humans

(2009) Nagy A. Farid et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Human plasma carboxylesterase 1, a novel serologic biomarker candidate for hepatocellular carcinoma

(2009) Keun Na et al.   PROTEOMICS

Structure and Catalytic Properties of Carboxylesterase Isozymes Involved in Metabolic Activation of Prodrugs

(2008) Masakiyo Hosokawa   MOLECULES