Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins

Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data

(2022) Bartosz Różycki et al.   BIOPHYSICAL CHEMISTRY

Identification and functional analysis of the SARS-COV-2 nucleocapsid protein

(2021) Tianyi Gao et al.   BMC MICROBIOLOGY

The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins

(2021) Kristina V. Tugaeva et al.   JOURNAL OF MOLECULAR BIOLOGY

Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms

(2021) Gergo Gogl et al.   Nature Communications

The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation

(2021) Zhihua Bai et al.   Viruses-Basel

The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors

(2021) Tomáš Otava et al.   ACS Infectious Diseases

14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites

(2021) Matej Horvath et al.   Communications Biology

Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response

(2021) François Enchéry et al.   Communications Biology

Reading the phosphorylation code: binding of the 14-3-3 protein to multivalent client phosphoproteins

(2020) Nikolai N. Sluchanko   BIOCHEMICAL JOURNAL

Henipavirus W proteins interact with 14-3-3 to modulate host gene expression.

(2020) Megan R. Edwards et al.   JOURNAL OF VIROLOGY

The Multifarious Role of 14-3-3 Family of Proteins in Viral Replication

(2020) Kavitha Ganesan Nathan et al.   Viruses-Basel

Mutations in the phosphorylation sites of SARS-CoV-2 encoded nucleocapsid protein and structure model of sequestration by protein 14-3-3

(2020) H.Y. Lim Tung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-resolution structures of the SARS-CoV-2 2′-O-methyltransferase reveal strategies for structure-based inhibitor design

(2020) Monica Rosas-Lemus et al.   Science Signaling

The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases

(2020) Veronika Obsilova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

(2020) Christopher R. Carlson et al.   MOLECULAR CELL

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity

(2019) William Riedl et al.   Cell Host & Microbe

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) – 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro

(2017) Dominika Chalupska et al.   JOURNAL OF STRUCTURAL BIOLOGY

Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1

(2017) Miroslava Alblova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology

(2016) Ivana Mejdrová et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structures of a yeast 14-3-3 protein fromLachancea thermotoleransin the unliganded form and bound to a human lipid kinase PI4KB-derived peptide reveal high evolutionary conservation

(2016) Andrea Eisenreichova et al.   Acta Crystallographica Section F-Structural Biology Communications

High-Risk Human Papillomavirus E6 Oncoproteins Interact with 14-3-3ζ in a PDZ Binding Motif-Dependent Manner

(2012) Siaw Shi Boon et al.   JOURNAL OF VIROLOGY

14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3)

(2010) Lenka Rezabkova et al.   JOURNAL OF STRUCTURAL BIOLOGY