Free Gangliosides Can Alter Amyloid-β Aggregation

Aβ–ganglioside interactions in the pathogenesis of Alzheimer's disease

(2020) Katsumi Matsuzaki   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity

(2020) Monica Bucciantini et al.   BIOPHYSICAL JOURNAL

Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

(2020) Michele F. Sciacca et al.   ACS Chemical Neuroscience

Analysis of Physicochemical Interaction of Aβ40 with a GM1 Ganglioside-Containing Lipid Membrane

(2018) Majid Vahed et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Phospholipids Critical Micellar Concentrations Trigger Different Mechanisms of Intrinsically Disordered Proteins Interaction with Model Membranes

(2018) Federica Scollo et al.   Journal of Physical Chemistry Letters

Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β

(2017) Kyle J. Korshavn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparing the Aggregation Free Energy Landscapes of Amyloid Beta(1–42) and Amyloid Beta(1–40)

(2017) Weihua Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the aggregation free energy landscape of the amyloid-β protein (1–40)

(2016) Weihua Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Do Membranes Initiate Alzheimer’s Disease? Formation of Toxic Amyloid Fibrils by the Amyloid β-Protein on Ganglioside Clusters

(2014) Katsumi Matsuzaki   ACCOUNTS OF CHEMICAL RESEARCH

Binding and Aggregation Mechanism of Amyloid β-Peptides onto the GM1 Ganglioside-Containing Lipid Membrane

(2013) Tyuji Hoshino et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alzheimer's disease (AD) as a disorder of the plasma membrane

(2013) Walter J. Lukiw   Frontiers in Physiology

GM1 Cluster Mediates Formation of Toxic Aβ Fibrils by Providing Hydrophobic Environments

(2012) Saori Fukunaga et al.   BIOCHEMISTRY

Small Amphipathic Molecules Modulate Secondary Structure and Amyloid Fibril-forming Kinetics of Alzheimer Disease Peptide Aβ1–42

(2012) Timothy M. Ryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DHPC Strongly Affects the Structure and Oligomerization Propensity of Alzheimer's Aβ(1–40) Peptide

(2010) Kirsten Dahse et al.   JOURNAL OF MOLECULAR BIOLOGY

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION