Multiple rare genetic variants co-segregating with familial IgA nephropathy all act within a single immune-related network

Aberrantly methylated DNA regions lead to low activation of CD4+ T-cells in IgA nephropathy

(2016) F. Sallustio et al.   CLINICAL SCIENCE

Intensive Supportive Care plus Immunosuppression in IgA Nephropathy

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

Novel genes and variants associated with IgA nephropathy by co-segregating with the disease phenotypes in 10 IgAN families

(2015) Ruihong Liu et al.   GENE

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

Estimating the mutation load in human genomes

(2015) Brenna M. Henn et al.   NATURE REVIEWS GENETICS

Genetic linkage analysis in the age of whole-genome sequencing

(2015) Jurg Ott et al.   NATURE REVIEWS GENETICS

Role of let-7b in the regulation ofN-acetylgalactosaminyltransferase 2 in IgA nephropathy

(2015) Grazia Serino et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients

(2015) Sharon N. Cox et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intensive Supportive Care plus Immunosuppression in IgA Nephropathy

(2015) Thomas Rauen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of new susceptibility loci for IgA nephropathy in Han Chinese

(2015) Ming Li et al.   Nature Communications

Genome-wide scan identifies a copy number variable region at 3p21.1 that influences the TLR9 expression levels in IgA nephropathy patients

(2014) Fabio Sallustio et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The genetics and immunobiology of IgA nephropathy

(2014) Krzysztof Kiryluk et al.   JOURNAL OF CLINICAL INVESTIGATION

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

(2014) Krzysztof Kiryluk et al.   NATURE GENETICS

IgA Nephropathy

(2013) Robert J. Wyatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Corticosteroid Therapy in IgA Nephropathy

(2012) J. Lv et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activated innate immunity and the involvement of CX3CR1–fractalkine in promoting hematuria in patients with IgA nephropathy

(2012) Sharon N. Cox et al.   KIDNEY INTERNATIONAL

Geographic Differences in Genetic Susceptibility to IgA Nephropathy: GWAS Replication Study and Geospatial Risk Analysis

(2012) Krzysztof Kiryluk et al.   PLoS Genetics

Linkage Analysis in the Next-Generation Sequencing Era

(2011) Joan E. Bailey-Wilson et al.   HUMAN HEREDITY

What can exome sequencing do for you?

(2011) J. Majewski et al.   JOURNAL OF MEDICAL GENETICS

The Pathophysiology of IgA Nephropathy

(2011) H. Suzuki et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy

(2011) Xue-Qing Yu et al.   NATURE GENETICS

Genome-wide association study identifies susceptibility loci for IgA nephropathy

(2011) Ali G Gharavi et al.   NATURE GENETICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Increased dimeric IgA-producing B cells in tonsils in IgA nephropathy determined by in situ hybridization for J chain mRNA

(2010) S. J. HARPER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

HLA Has Strongest Association with IgA Nephropathy in Genome-Wide Analysis

(2010) J. Feehally et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Altered modulation of WNT–β-catenin and PI3K/Akt pathways in IgA nephropathy

(2010) Sharon N. Cox et al.   KIDNEY INTERNATIONAL

Reconciling the analysis of IBD and IBS in complex trait studies

(2010) Joseph E. Powell et al.   NATURE REVIEWS GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

The incidence of primary glomerulonephritis worldwide: a systematic review of the literature

(2010) A. McGrogan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Genetic studies of IgA nephropathy: past, present, and future

(2010) Krzysztof Kiryluk et al.   PEDIATRIC NEPHROLOGY

The ubiquitin-proteasome pathway and IgA nephropathy: a novel link?

(2009) Sydney C.W. Tang et al.   KIDNEY INTERNATIONAL

Randomized controlled clinical trial of corticosteroids plus ACE-inhibitors with long-term follow-up in proteinuric IgA nephropathy

(2009) C. Manno et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy

(2008) Rosanna Coppo et al.   KIDNEY INTERNATIONAL

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

Racial and Genetic Factors in IgA Nephropathy

(2008) Stephen I.-Hong Hsu   SEMINARS IN NEPHROLOGY