Article
Materials Science, Ceramics
P. C. Nagajyothi, P. Muthuraman, C. O. Tettey, K. Yoo, Jaesool Shim
Summary: ZnO/Ag nanocomposites were synthesized using a green method with various Ag contents, leading to changes in surface, structural, morphological, and bio-activities. Among the composites, ZnO/Ag 7.5 showed superior anticancer activity against HeLa and SKOV-3 cell lines, reducing cell viability and ATP contents while increasing ROS generation in a dose-dependent manner.
CERAMICS INTERNATIONAL
(2021)
Article
Nanoscience & Nanotechnology
Zhao Li, Iftikhar Ali, Jiying Qiu, Huanzhu Zhao, Wenya Ma, Aiying Bai, Daijie Wang, Jingchao Li
Summary: The study synthesized DMY-AgNPs for their antioxidant, antibacterial, and anticancer properties. The results demonstrated that DMY-AgNPs exhibited strong antioxidant, antibacterial, and anticancer effects.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Mukul Gupta, Javed Sheikh, Annu, Ankit Singh
Summary: The study developed a multifunctional finished linen fabric using an environment-friendly approach by modifying cellulose-based linen fabric with amino polysaccharide, zinc oxide nanoparticles, and flower extract. The modified fabric exhibited effective crease recovery, increased UV protection factor, excellent antibacterial activity, and high free radical scavenging ability. The durability of the multifunctional properties was also confirmed after several launderings.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Polymer Science
Ayed S. Allogmani, Roushdy M. Mohamed, Mohamed S. Hasanin
Summary: This study examined the preparation of biomaterial-based multifunctional biopolymers via an eco-friendly formulation method using ultrasound. The formulated nanocomposite showed a thermally stable nanostructure and demonstrated excellent cytocompatibility, antimicrobial activity, and antioxidant activity.
Article
Nanoscience & Nanotechnology
Chandrashekar Srinivasa, S. R. Santosh Kumar, Sushma Pradeep, Shashanka K. Prasad, Ravindra Veerapur, Mohammad Azam Ansari, Mohammad N. Alomary, Saad Alghamdi, Mazen Almehmadi, G. C. Kavitha, Azharuddin B. Daphedar, Siddappa B. Kakkalameli, Chandan Shivamallu, Shiva Prasad Kollur
Summary: This study synthesized manganese oxide nanoparticles using Gmelina arborea fruit extract and evaluated their anticancer efficacy. The results showed that the MnO2 NPs exhibited significant inhibition against MCF-7 breast cancer cells.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Maged S. Al-Fakeh, Samir Osman Mohammed Osman, Malek Gassoumi, Mokded Rabhi, Mohamed Omer
Summary: Palladium nanoparticles (Pd-NPs) synthesized using Saudi propolis exhibit environmental, fast, controlled, and cost-effective characteristics; the average particle size of Pd-NPs ranges from 3.14 to 4.62 nm, at the quantum scale; Saudi propolis-derived Pd-NPs demonstrate enhanced antimicrobial and anticancer activities.
Article
Chemistry, Multidisciplinary
Monika Ivanusa, Blazka Kumer, Elizabeta Petrovcic, Danaja Stular, Matija Zorc, Ivan Jerman, Marija Gorjanc, Brigita Tomsic, Barbara Simoncic
Summary: This study developed a novel and environmentally friendly method for producing durable antimicrobial and UV blocking coatings on cotton fabrics through in situ biosynthesis of silver nanoparticles. The results showed excellent properties of the coatings even after multiple washes.
Article
Chemistry, Multidisciplinary
Johar Amin Ahmed Abdullah, Mercedes Jimenez Rosado, Antonio Guerrero, Alberto Romero
Summary: This study aims to investigate the green synthesis of ZnO-NPs using a polyphenol-rich extract from Phoenix dactylifera L. as a reducing agent. The effects of precursor and reducing agent concentration were evaluated, and it was found that using a green reducing agent resulted in ZnO-NPs with a particle size ranging from 18.1 to 61.6 nm. The synthesized nanoparticles demonstrated antioxidant and antibacterial activities. Therefore, this method could be a suitable alternative to toxic methods for metallic nanoparticle synthesis.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Polymer Science
Muhammad Usman Munir, Daiva Mikucioniene, Haleema Khanzada, Muhammad Qamar Khan
Summary: Due to the current COVID-19 pandemic, there is a crucial need for the development of antimicrobial and antiviral personal protective equipment. In this research, electrospun nanofibers composite with polyvinyl alcohol, aloe vera, and zinc oxide nanoparticles were fabricated for medical device applications. The results showed that increasing the concentration of zinc oxide in the nanofibers was more effective in killing and inhibiting bacterial growth compared to increasing the concentration of aloe vera.
Review
Chemistry, Inorganic & Nuclear
Priyanka Panchal, Rishabh Sharma, A. Sudharshan Reddy, Kiran Nehra, Anshu Sharma, S. P. Nehra
Summary: Researchers have been exploring the potential of nanomaterials-based solutions to combat environmental issues. Our team has synthesized photocatalytic nanomaterials and nanocomposites using plant extracts, which are cost-effective, non-toxic, and highly stable. This review examines the synthesis methods, applications, and green approaches for these materials, aiming to enhance understanding and future research.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Polymer Science
E. M. Abdelfattah, H. Elzanaty, W. B. Elsharkawy, M. A. Azzam, Z. M. Elqahtani, S. Alotibi, M. Alyami, T. Fahmy
Summary: Poly (vinyl alcohol)/chitosan/ZnO (PVA/Cs/ZnO) nanocomposite films were prepared through an environmentally friendly approach and characterized using various techniques. The results showed that the PVA/Cs blend matrix encapsulated the ZnO nanoparticles. The addition of ZnO NPs increased the glass transition and melting temperature values of the PVA/Cs blend. The ATR-FTIR spectra indicated the existence of hydrogen bonding between the OH groups of PVA/Cs and ZnO nanoparticles. The nanocomposites exhibited better thermal stability and enhanced optical properties with increasing concentration of ZnO nanoparticles. Moreover, PVA/Cs/ZnO nanocomposites showed significant antibacterial activity.
Article
Chemistry, Inorganic & Nuclear
Kattakgoundar Govindaraj Sudha, Saheb Ali, Gopalu Karunakaran, Mariyappan Kowsalya, Evgeny Kolesnikov, Mikhail Gorshenkov, Thangavel Velmurugan, Mohan Prasanna Rajeshkumar
Summary: This study successfully synthesized ZnO nanorods using plant aqueous leaf extracts, with promising applications in biomedical and cancer treatment. The ZnO nanorods exhibited non-toxic behavior, anticancer properties, bactericidal effects, as well as antioxidant and photocatalytic activities. The green-synthesized ZnO nanorods show potential for implementation in medicinal areas.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Pharmacology & Pharmacy
Maqusood Ahamed, Mohd Javed Akhtar, M. A. Majeed Khan, Hisham A. Alhadlaq
Summary: In this study, cobalt-doped Bi2O3/reduced graphene oxide (Co-Bi2O3/RGO) nanocomposites were green synthesized using garlic extract as reducing and capping agents. The Co-Bi2O3/RGO NCs showed stronger antimicrobial and anticancer activities compared to Bi2O3 NPs, with better biocompatibility towards normal cells. This study highlights the importance of facile and cost-effective medicinal plant-based synthesis of novel nanocomposites for biomedical applications.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Maqusood Ahamed, Mohd Javed Akhtar, M. A. Majeed Khan, Hisham A. Alhadlaq
Summary: This study prepared pure ZnO nanoparticles, Mo-doped ZnO nanoparticles, and Mo-ZnO/reduced graphene oxide nanocomposites using a green and easy method with date palm fruit extract. The green synthesized Mo-ZnO/RGO nanocomposites exhibited enhanced anticancer activity and improved cytocompatibility compared to pure ZnO nanoparticles. The potential anticancer mechanism of Mo-ZnO/RGO nanocomposites was explored through oxidative stress and apoptosis. The findings suggest the potential of fruit-based facile preparation of ZnO-based nanocomposites for cancer therapy.
Article
Nanoscience & Nanotechnology
Helal F. Al-Harthi, Abu Baker, Abdallah M. Elgorban, Ali H. Bahkali, Ayaz Mukarram Shaikh, Bela Kovacs, Mohd Sajid Khan, Asad Syed
Summary: In this study, a novel fungus Alternaria sp. was isolated and characterized from the vicinity of medicinal plants, and its extracted proteins were used to synthesize highly biocompatible zinc nanoparticles. The synthesized particles were characterized using various physical techniques and were found to possess regular crystallinity and antibacterial and anticancer activities.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
Article
Environmental Sciences
K. Ramesh kumar, V. Anbazhagan
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2018)
Article
Optics
V. Anbazhagan, R. Renganathan
JOURNAL OF LUMINESCENCE
(2008)
Article
Optics
V. Anbazhagan, R. Renganathan
JOURNAL OF LUMINESCENCE
(2009)
Article
Chemistry, Physical
A. Kathiravan, V. Anbazhagan, M. Asha Jhonsi, R. Renganathan
JOURNAL OF MOLECULAR STRUCTURE
(2009)
Article
Chemistry, Physical
V. Anbazhagan, V. Kandavelu, A. Kathiravan, R. Renganathan
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2008)
Article
Chemistry, Medicinal
Anusuya Shanmugam, Venkattappan Anbazhagan, Jeyakumar Natarajan
MEDICINAL CHEMISTRY RESEARCH
(2012)
Article
Chemistry, Physical
A. Kathiravan, V. Anbazhagan, M. Asha Jhonsi, R. Renganathan
ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS
(2008)
Article
Chemistry, Physical
A. Kathiravan, V. Anbazhagan, M. Asha Jhonsi, R. Renganathan
ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS
(2008)
Article
Chemistry, Inorganic & Nuclear
Muniyappan Thirumal, Anbazhagan Venkattappan, Galmari Venkatachalam
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2020)
Article
Biochemical Research Methods
Kandavelu Velappan, Renganathan Rajalingam, Anbazhagan Venkattappan
Summary: The interactions between zeolite adsorbed porphyrins and antioxidants were investigated, and the prepared porphyrins were characterized. The study showed that zinc porphyrin has a more effective quenching effect compared to free base porphyrin, and the quenching reaction involves electron transfer from quenchers to the excited singlet state of porphyrins.
JOURNAL OF FLUORESCENCE
(2021)
Review
Chemistry, Medicinal
Anusuya Shanmugam, Anbazhagan Venkattappan, M. Michael Gromiha
Summary: The COVID-19 pandemic has led to increased research on the SARS-CoV-2 spike protein for drug design. This review summarizes various structure-based drug design approaches applied to this protein, including molecular docking, virtual screening, molecular dynamics simulation, drug repurposing, and pharmacophore modeling and screening.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Senthilkumar Chandrasekaran, Venkattappan Anbazhagan
Summary: The study focused on synthesizing zinc oxide (ZnO) and vanadium-doped zinc oxide (V-ZnO) nanoparticles using Vinca rosea leaf extract. The chemical composition, structural, and morphological properties of the nanoparticles were examined using FTIR, XRD, and SEM-EDX. The results confirmed the presence of ZnO and V-ZnO nanoparticles and showed their hexagonal crystal structure. The cytotoxic effect of the nanoparticles was tested on breast cancer cells, and the Vinca rosea capped ZnO nanoparticles exhibited higher cytotoxic activity compared to the Vinca rosea capped V-ZnO nanoparticles. The nanoparticles also demonstrated strong antibacterial activity and antidiabetic properties.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Physical
G. Kanagasabapathy, S. Britto, V. Anbazhagan
Summary: This study presents a new method for synthesizing a series of 2-aminothiazole derivatives by cyclocondensation reaction of thiourea with appropriate acid halides followed by condensation with highly functionalized amines. The synthesized products were characterized and evaluated for their antibacterial and antifungal activity against Bacillus cereus and Candida albicans. In silico analysis demonstrated acceptable binding interactions of the derived products with the active sites of the pathogens.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Review
Chemistry, Inorganic & Nuclear
Sahana Sadhasivam, Megala Shanmugam, Pillai Divya Umamaheswaran, Anbazhagan Venkattappan, Anusuya Shanmugam
Summary: Nanoparticles are ultrafine particles with particle size at nanoscale, and when metals and metal oxides are synthesized at this scale, their unique properties have led to diverse applications in industries such as food, textile, cosmetic, automobile and pharmaceuticals. Among these, zinc oxide nanoparticles have various applications in biomedical fields, including antibacterial, antifungal, anticancer, anti-inflammatory and wound healing properties.
JOURNAL OF CLUSTER SCIENCE
(2021)
Article
Chemistry, Physical
Xinlei Chen, Shiyi Chen, Xuele Lin, Jingxuan Zhou, Xingjun Gao, Yaoqi Zhen, Xiaodan Ma, Shouwen Jin, Linfang Shi, Hui Liu, Daqi Wang
Summary: Nine mixed-ligand Cd2+ complexes with different geometric structures were synthesized and characterized. The complexes exhibit various coordination modes and form both intra- and intermolecular hydrogen bonds.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Rupali Mahajan, Abhishek Sharma, Bhagyashree Patra, Lijo Mani, Parul Grover, Sandeep Kumar, Santosh Kumar Guru, Gananadhamu Samanthula, Amol G. Dikundwar, Amit Asthana
Summary: This research article provides a comprehensive characterization and toxicological assessment of a photoisomeric impurity of the antianemic drug Roxadustat. The impurity has a distinct structure compared to the drug and its formation due to light exposure is a concern. Through various experiments, including single crystal XRD, physicochemical characterization, and in vitro cytotoxicity assays, the researchers confirmed the structure of the impurity, evaluated its conversion with Roxadustat, and assessed its toxicological activity. These findings contribute to the understanding of drug stability, safety, and formulation development.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Laila S. Alqarni, Azzah M. Alghamdi, Nuha Y. Elamin, A. Rajeh
Summary: The solution casting method was used to produce a new type of nanocomposites made of chitosan, gelatin, and co-doped ZnO nanoparticles. The addition of 3.5% co-doped ZnO nanoparticles improved the physicochemical characteristics and antimicrobial effects of the nanocomposites, indicating their significant potential in food packaging and energy storage.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ruchi Gaur
Summary: The structure and intermolecular interactions of a newly synthesized bis-chalcone THXA were studied using experimental and computational methods. The importance of non-covalent interactions such as pi center dot center dot center dot pi, C-H center dot center dot center dot S, and C-H center dot center dot center dot pi was revealed.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Andrii Bazylevich, Leonid Patsenker, Sarit Aviel-Ronen, Gary Gellerman
Summary: Drug combination therapy is commonly used for treating various skin disorders, but its effectiveness is often limited. In this study, researchers synthesized conjugates of anti-pigmenting drugs and hyaluronic acid (HA) to improve treatment efficacy. These HA-drug conjugates exhibited measurable drug release profiles and demonstrated superior depigmentation effects compared to control groups in a swine model.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Xiaodan Ma, Xinlei Chen, Yaoqi Zhen, Xunjie Zheng, Chengzhe Shi, Shouwen Jin, Bin Liu, Bin Chen, Daqi Wang
Summary: Cocrystallization experiments between minoxidil and aryl acids coformers resulted in the successful formation of multi-component samples. The nature of these samples was determined using various techniques and their structural and supramolecular aspects were investigated. The outcomes revealed the importance of nonbonding contacts and different types of interactions in stabilizing and expanding the crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Najla A. Alshaye, Magdy A. Ibrahim, Al-Shimaa Badran
Summary: The chemical behavior of 3-substituted-6,8-dimethylchromones towards phenylhydrazine was examined. Different reaction conditions produced various products, and the molecular geometries and reactivity descriptors of the compounds were also investigated. The results suggest that these compounds are suitable for nonlinear optical applications.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Hayette Alliouche, Houria Bouria, Rafik Bensegueni, Mounia Guergouri, Abdelmalek Bouraiou, Ali Belfaitah
Summary: In this paper, a combined experimental and theoretical study was conducted to synthesize and characterize new 2-quinolone-piperidine and -morpholine hybrids. The results from experiments were validated using computational calculations, and the affinity between these compounds and Acetylcholinesterase/Butyrylcholinesterase was estimated through molecular docking.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-Lai Liu, Jian-Ling Ni, Li-Zhuang Chen, Qiang Gao, Fang-Ming Wang
Summary: This study synthesized and characterized a novel Mn-based LMOF, and achieved good results in detecting heavy metal Al3+ in water, showing good stability, high selectivity and sensitivity. This provides new insights into the potential applications of Mn-based MOFs in chemical sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Jun-Xia Li, Yi-Jing Lu, Ke-Ying Quan, Li-Bing Wu, Xun Feng, Wei-Zhou Wang
Summary: This study synthesized two cobalt(II) complexes and analyzed their crystal structures using single-crystal X-ray diffraction. The results showed that the crystal structures of these complexes were different, and they exhibited different crystal packing and magnetic properties.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Yang Li, Yan Zhang, Hong Xu, Min Li, Zhen Li, Zi-yu Song, Ji-shi Chen, Yan-Jun Liu, Yong Sun, Zhao Yang
Summary: This study reports the synthesis and solid-state characterization of a new pharmaceutical cocrystal, PRO-BPE, which can enhance the solubility of the highly water-insoluble prodrug probenecid. The PRO-BPE cocrystals were found to have superior water solubility compared to pure PRO. This research provides valuable insights into improving the solubility of poorly soluble drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Lucas G. B. Felicio, Bianca B. M. Vieira, Ivana S. Lula, Renata Diniz, Frank Alexis, Flavio B. Miguz, Frederico B. De Sousa
Summary: A novel spiropyran derivative was synthesized for heavy metals sensing in water. The results demonstrated that the new derivative can serve as a rapid, sensitive, and simple tool for detecting Hg2+ ions in water with high selectivity.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Junqing Meng, Jie Wang, Lijuan Wang, Chunhui Lyu, Haiyan Chen, Yingpei Lyu, Baisheng Nie
Summary: Material modification with low surface energy can achieve lower surface free energy on micro-and nano-rough structures, which is crucial for developing superhydrophobic surfaces. In this study, attapulgite (APT) was modified with alkylamine, alkylammonium salt, and stearic acid, and the interaction between low surface materials and attapulgite was explained. The results showed that the hydrophobicity of APT was significantly modified by the modifiers, and the surface free energy of the composites first decreased and then increased with increasing molecular number of low surface energy monomers.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Karan Goswami, Dipak Das, Parthasarathi Bera, Sounak Roy, Md. Motin Seikh, Prasanta Kumar Sinha, Arup Gayen
Summary: This work presents the development of a simple and highly active heterogeneous Pd catalyst for Suzuki-Miyaura carbon-carbon cross-coupling reaction. The NiPdFe-1 catalyst shows the best activity and stability among the prepared catalysts. It efficiently promotes the coupling reaction between aryl bromide and phenyl boronic acid under mild reaction conditions with high isolated yields.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ekta Pardhi, Devendra Singh Tomar, Rahul Khemchandani, Gananadhamu Samanthula, Pankaj Kumar Singh, Neelesh Kumar Mehra
Summary: The main aim of this study was to prepare a drug-drug coamorphous system to improve the physiochemical properties, solubility and stability of Apremilast and Indomethacin. Various solid-state characterization techniques were used to characterize the prepared system. Molecular level interactions were studied using molecular modeling and ATR-FTIR and 1H NMR. Solubility and dissolution studies showed the benefits of the coamorphous system. The system was found to be stable for a period of five months. Permeation study also demonstrated improved flux for both drugs compared to their crystalline forms. The coamorphous system showed anti-psoriatic and anti-melanogenic activity based on molecular docking results. Overall, the developed CAM-based supersaturated system exhibited improved physicochemical properties and physical stability.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
