Benzotriazole-oxadiazole hybrid Compounds: Synthesis, anticancer Activity, molecular docking and ADME profiling studies

Synthesis and docking calculations of tetrafluoronaphthalene derivatives and their inhibition profiles against some metabolic enzymes

(2021) Musa Erdoğan et al.   ARCHIV DER PHARMAZIE

Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents

(2021) Sevtap Çağlar Yavuz et al.   SYNTHETIC COMMUNICATIONS

Investigation of structural, electronical and in vitro cytotoxic activity properties of some heterocyclic compounds

(2021) Senem Akkoç et al.   JOURNAL OF MOLECULAR STRUCTURE

Biological Activity and Molecular Docking Study of Some Bicyclic Structures: Antidiabetic and Anticholinergic Potentials

(2021) Parham Taslimi et al.   POLYCYCLIC AROMATIC COMPOUNDS

Structurally diverse heterobimetallic Pb(II)-Salen complexes mechanistic notion of cytotoxic activity against neuroblastoma cancer cell: Synthesis, characterization, protein–ligand interaction profiler, and intuitions from DFT

(2021) Dhrubajyoti Majumdar et al.   POLYHEDRON

Some old 2-(4-(Aryl)- thiazole-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-tethanoisoindole-1,3(2H)-dione derivatives: Synthesis, inhibition effects and molecular docking studies on Aldose reductase and α-Glycosidase

(2021) Parham TASLIMI et al.   Cumhuriyet Science Journal

Selective cytotoxicity of marine-derived fungal metabolite (3S,6S)-3,6-dibenzylpiperazine-2,5-dione against cancer cells adapted to nutrient starvation

(2020) Rui Tang et al.   JOURNAL OF ANTIBIOTICS

Diltiazem potentiates the cytotoxicity of gemcitabine and 5-fluorouracil in PANC-1 human pancreatic cancer cells through inhibition of P-glycoprotein

(2020) Hesham A. El-Mahdy et al.   LIFE SCIENCES

Synergistic Anticancer Effect of Gemcitabine Combined With Impressic Acid or Acankoreanogein in Panc-1 Cells by Inhibiting NF-κB and Stat 3 Activation

(2020) Sen Jiang et al.   Natural Product Communications

Quinolone hybrids and their anti-cancer activities: An overview

(2019) Feng Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies

(2019) Arif Mermer et al.   BIOORGANIC CHEMISTRY

Synthesis of novel Schiff bases using green chemistry techniques; antimicrobial, antioxidant, antiurease activity screening and molecular docking studies

(2019) Arif Mermer et al.   JOURNAL OF MOLECULAR STRUCTURE

Oxadiazole scaffolds in anti-tuberculosis drug discovery

(2019) Suparna S. De et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Novel Sulfonamide‐Based 5‐Arylidenerhodanines as Effective Carbonic Anhydrase (II) Inhibitors: Microwave‐Assisted and Ultrasound‐Assisted One‐Pot Four‐Component Synthesis, Molecular Docking, and Anti‐CA II Screening Studies

(2019) Arif Mermer et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Antifungal activity of two oxadiazole compounds for the paracoccidioidomycosis treatment

(2019) Franciele Abigail Vilugron Rodrigues-Vendramini et al.   PLoS Neglected Tropical Diseases

2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

(2019) Dongsheng Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preparation and Characterization of Magnetic Fe3O4/CdWO4 and Fe3O4/CdWO4/PrVO4 Nanoparticles and Investigation of Their Photocatalytic and Anticancer Properties on PANC1 Cells

(2019) Marsooli et al.   Materials

Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors

(2018) Mehlika Dilek Altıntop et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological activity and structure activity relationship studies of novel conazole analogues via conventional, microwave and ultrasound mediated techniques

(2018) Arif Mermer et al.   BIOORGANIC CHEMISTRY

Research advances on anticancer activities of matrine and its derivatives: An updated overview

(2018) Haroon ur Rashid et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The potential role of tubeimosides in cancer prevention and treatment

(2018) Md Sodrul Islam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluoroquinolone-isatin hybrids and their biological activities

(2018) Zhi Xu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Combination therapy for the treatment of pancreatic cancer through hyaluronic acid-decorated nanoparticles loaded with quercetin and gemcitabine: A preliminary in vitro study

(2018) Carla Serri et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Recent advances (2015–2016) in anticancer hybrids

(2017) Nagaraju Kerru et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, characterization, and molecular modeling studies of novel oxadiazole derivatives of nipecotic acid as potential anticonvulsant and antidepressant agents

(2017) Ravi Bhushan Singh et al.   MEDICINAL CHEMISTRY RESEARCH

Anticancer potential of bioactive peptides from animal sources

(2017) Linghong Wang et al.   ONCOLOGY REPORTS

Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and their Structure-activity Relationship

(2017) Zhi-Xing Qing et al.   CURRENT MEDICINAL CHEMISTRY

Hybrid molecules: The privileged scaffolds for various pharmaceuticals

(2016) Shaveta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Epidemiology of pancreatic cancer

(2016) Milena Ilic et al.   WORLD JOURNAL OF GASTROENTEROLOGY

1,3,4-Oxadiazole derivatives as potential antitumor agents: discovery, optimization and biological activity valuation

(2016) Yin Luo et al.   MedChemComm

Identification of pyrazolopyridazinones as PDEδ inhibitors

(2016) Björn Papke et al.   Nature Communications

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Benzotriazole: An overview on its versatile biological behavior

(2015) I. Briguglio et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of some novel thiazole substituted benzotriazole derivatives

(2012) Nitin D. Gaikwad et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis and Antifungal Activity of Some New Imidazole and Triazole Derivatives

(2011) Zahra Rezaei et al.   ARCHIV DER PHARMAZIE

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Synthesis of some novel triazole derivatives as anti-nociceptive and anti-inflammatory agents

(2009) Aiyalu Rajasekaran et al.   ACTA PHARMACEUTICA

Hybrid Molecules with a Dual Mode of Action: Dream or Reality?†

(2007) Bernard Meunier   ACCOUNTS OF CHEMICAL RESEARCH