Transcriptomic, Epigenomic, and Neuroanatomic Signatures Differ in Chronic Prurigo, Atopic Dermatitis, and Brachioradial Pruritus

Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization

(2021) Micah Belzberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transcriptomic characterization of prurigo nodularis and the therapeutic response to nemolizumab

(2021) Lam C. Tsoi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic Nodular Prurigo: Clinical Profile and Burden. A European Cross‐sectional Study

(2020) M.P. Pereira et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Abnormal Reinnervation of Denervated Areas Following Nerve Injury Facilitates Neuropathic Pain

(2020) Hodaya Leibovich et al.   Cells

Keratin 17 is induced in prurigo nodularis lesions

(2020) Li-Li Yang et al.   Open Chemistry

A position paper on the management of itch and pain in atopic dermatitis from the International Society of Atopic Dermatitis (ISAD)/Oriented Patient‐Education Network in Dermatology (OPENED) task force

(2020) L. Misery et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

DNA methylation profiles are associated with complex regional pain syndrome following traumatic injury

(2019) Stephen Bruehl et al.   PAIN

Peripheral sensitisation and loss of descending inhibition is a hallmark of chronic pruritus

(2019) Esther M. Pogatzki-Zahn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Contribution of DNMT1 to neuropathic pain genesis partially through epigenetically repressing Kcna2 in primary afferent neurons

(2019) Linlin Sun et al.   JOURNAL OF NEUROSCIENCE

Pathophysiological mechanisms of itch in bullous pemphigoid

(2019) Takashi Hashimoto et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Keratin 6, 16 and 17—Critical Barrier Alarmin Molecules in Skin Wounds and Psoriasis

(2019) Xiaowei Zhang et al.   Cells

Clinical characteristics, symptoms and burden of psoriasis and atopic dermatitis in adults

(2019) A. Egeberg et al.   BRITISH JOURNAL OF DERMATOLOGY

Skin DNA methylation profile in atopic dermatitis patients: A case–control study

(2019) Olga Yu. Olisova et al.   EXPERIMENTAL DERMATOLOGY

The Genetics of Chronic Itch: Gene Expression in the Skin of Patients with Atopic Dermatitis and Psoriasis with Severe Itch

(2018) Leigh A. Nattkemper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Application of an 8% capsaicin patch normalizes epidermal TRPV1 expression but not the decreased intraepidermal nerve fibre density in patients with brachioradial pruritus

(2018) M.P. Pereira et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Three-dimensional optical clearing and imaging of pruritic atopic dermatitis and psoriasis skin reveals downregulation of epidermal innervation

(2018) Yingrou Tan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury

(2018) Georgios Baskozos et al.   PAIN

There is no functional small-fibre neuropathy in prurigo nodularis despite neuroanatomical alterations

(2017) Manuel P. Pereira et al.   EXPERIMENTAL DERMATOLOGY

Epigenetics insights into chronic pain

(2017) Daniel Ciampi de Andrade et al.   PAIN

Intraepidermal Nerve Fibre Density is Decreased in Lesional and Inter-lesional Prurigo Nodularis and Reconstitutes on Healing of Lesions

(2016) S Bobko et al.   ACTA DERMATO-VENEREOLOGICA

The pruritus- and T H 2-associated cytokine IL-31 promotes growth of sensory nerves

(2016) Micha Feld et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice

(2016) Bao-Chun Jiang et al.   JOURNAL OF NEUROSCIENCE

Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways

(2015) Debajyoti Ghosh et al.   PLoS One

Assessment of sensory thresholds and nociceptive fiber growth after sciatic nerve injury reveals the differential contribution of collateral reinnervation and nerve regeneration to neuropathic pain

(2014) Stefano Cobianchi et al.   EXPERIMENTAL NEUROLOGY

NF- B controls axonal regeneration and degeneration through cell-specific balance of RelA and p50 in the adult CNS

(2014) R. Haenold et al.   JOURNAL OF CELL SCIENCE

An Integrated Epigenetic and Transcriptomic Analysis Reveals Distinct Tissue-Specific Patterns of DNA Methylation Associated with Atopic Dermatitis

(2014) Elke Rodríguez et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epigenetic Modification of Spinal miR-219 Expression Regulates Chronic Inflammation Pain by Targeting CaMKII 

(2014) Z. Pan et al.   JOURNAL OF NEUROSCIENCE

Aberrant epidermal expression of semaphorin 3A and nerve growth factor in prurigo nodularis

(2013) Shinnosuke Takada et al.   JOURNAL OF DERMATOLOGY

Artemin induced functional recovery and reinnervation after partial nerve injury

(2013) Ruizhong Wang et al.   PAIN

PGP 9.5 distribution patterns in biopsies from early lesions of atopic dermatitis

(2012) Lennart Emtestam et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Atopic Keratinocytes Induce Increased Neurite Outgrowth in a Coculture Model of Porcine Dorsal Root Ganglia Neurons and Human Skin Cells

(2012) Dennis Roggenkamp et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats

(2012) Feihu Qi et al.   PAIN

The Neuronal EGF-Related Gene Nell2 Interacts with Macf1 and Supports Survival of Retinal Ganglion Cells after Optic Nerve Injury

(2012) Yasunari Munemasa et al.   PLoS One

Retrospective Study of Intraepidermal Nerve Fiber Distribution in Biopsies of Patients With Nummular Eczema

(2011) Ben Maddison et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Reduced intraepidermal nerve fibre density in lesional and nonlesional prurigo nodularis skin as a potential sign of subclinical cutaneous neuropathy

(2011) B. Schuhknecht et al.   BRITISH JOURNAL OF DERMATOLOGY

Psoralen-ultraviolet A therapy alters epidermal Sema3A and NGF levels and modulates epidermal innervation in atopic dermatitis

(2009) Mitsutoshi Tominaga et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Nuclear Factor-κB Activation in Axons and Schwann Cells in Experimental Sciatic Nerve Injury and Its Role in Modulating Axon Regeneration: Studies With Etanercept

(2009) Darrell Smith et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Decreased production of semaphorin 3A in the lesional skin of atopic dermatitis

(2008) M. Tominaga et al.   BRITISH JOURNAL OF DERMATOLOGY