BML‐260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability

Ex vivo expansion of hematopoietic stem cells: Finally transitioning from the lab to the clinic

(2021) Eran Zimran et al.   BLOOD REVIEWS

Small molecule‐mediated modulation of ubiquitination and neddylation improves HSC function ex vivo

(2021) Esra Albayrak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell

(2021) Jiaxing Li et al.   Acta Pharmaceutica Sinica B

Temporal modulation of calcium sensing in hematopoietic stem cells is crucial for proper stem cell expansion and engraftment

(2020) Merve Uslu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Skp2 in the ubiquitin‐proteasome system: A comprehensive review

(2020) Moges Dessale Asmamaw et al.   MEDICINAL RESEARCH REVIEWS

Haematopoietic stem cell self-renewal in vivo and ex vivo

(2020) Adam C. Wilkinson et al.   NATURE REVIEWS GENETICS

Development of Small Molecule MEIS Inhibitors that modulate HSC activity

(2020) Raife Dilek Turan et al.   Scientific Reports

Effects of tosyl-l-arginine methyl ester (TAME) on the APC/c subunits: An in silico investigation for inhibiting cell cycle

(2020) Mahya Marashiyan et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Allogeneic human umbilical cord Wharton’s jelly stem cells increase several-fold the expansion of human cord blood CD34+ cells both in vitro and in vivo

(2020) Hao Daniel Lin et al.   Stem Cell Research & Therapy

Targeting JNK pathway promotes human hematopoietic stem cell expansion

(2019) Xiong Xiao et al.   Cell Discovery

Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche

(2019) Parisa Tajer et al.   Cells

JNK signaling in cancer cell survival

(2019) Qinghua Wu et al.   MEDICINAL RESEARCH REVIEWS

Cord blood research, banking, and transplantation: achievements, challenges, and perspectives

(2019) Hector Mayani et al.   BONE MARROW TRANSPLANTATION

Synthesis and evaluation of pyrimidoindole analogs in umbilical cord blood ex vivo expansion

(2019) Yue Feng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hematopoietic stem cell fate through metabolic control

(2018) Kyoko Ito et al.   EXPERIMENTAL HEMATOLOGY

c-Myc inhibitor 10074-G5 induces murine and human hematopoietic stem and progenitor cell expansion and HDR modulator Rad51 expression

(2018) Merve Aksoz et al.   CURRENT CANCER DRUG TARGETS

Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail

(2018) Mengmeng Jiang et al.   Cell Discovery

HSC Niche Biology and HSC Expansion Ex Vivo

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Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

(2016) John E. Wagner et al.   Cell Stem Cell

Novel chemical attempts at ex vivo hematopoietic stem cell expansion

(2016) Yu Zhang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion

(2016) Marina Tarunina et al.   STEM CELLS AND DEVELOPMENT

Hypoxic metabolism in human hematopoietic stem cells

(2015) Fatih Kocabas et al.   Cell and Bioscience

A plea to reduce or replace fetal bovine serum in cell culture media

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Hematopoietic Stem Cells: Transcriptional Regulation, Ex Vivo Expansion and Clinical Application

(2011) R. Aggarwal et al.   CURRENT MOLECULAR MEDICINE

Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment

(2011) Tony Peled et al.   EXPERIMENTAL HEMATOLOGY

Reactive oxygen species and hematopoietic stem cell senescence

(2011) Lijian Shao et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Human umbilical cord Wharton's jelly stem cells and its conditioned medium support hematopoietic stem cell expansion ex vivo

(2011) C.Y. Fong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The emerging role of APC/CCdh1 in development

(2011) Dong Hu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Inhibition of p38 Mitogen-Activated Protein Kinase Promotes Ex Vivo Hematopoietic Stem Cell Expansion

(2011) Yong Wang et al.   STEM CELLS AND DEVELOPMENT

Ex vivo expansion of umbilical cord blood for transplantation

(2010) S.S. Tung et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Characterization of a GSK-3 inhibitor in culture of human cord blood primitive hematopoietic cells

(2010) Junfen Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Pharmacologic modulation of the calcium-sensing receptor enhances hematopoietic stem cell lodgment in the adult bone marrow

(2010) B. S. Lam et al.   BLOOD

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Interplay between Cdh1 and JNK activity during the cell cycle

(2010) Gustavo J. Gutierrez et al.   NATURE CELL BIOLOGY

Selective Enhancement of Donor Hematopoietic Cell Engraftment by the CXCR4 Antagonist AMD3100 in a Mouse Transplantation Model

(2010) Yubin Kang et al.   PLoS One

Control of cell growth by the SCF and APC/C ubiquitin ligases

(2009) Jeffrey R Skaar et al.   CURRENT OPINION IN CELL BIOLOGY

In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood

(2009) Christopher Y Park et al.   Nature Protocols

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL