DarT-mediated mtDNA damage induces dynamic reorganization and selective segregation of mitochondria

Distinct fission signatures predict mitochondrial degradation or biogenesis

(2021) Tatjana Kleele et al.   NATURE

Molecular basis for DarT ADP-ribosylation of a DNA base

(2021) Marion Schuller et al.   NATURE

Cristae-dependent quality control of the mitochondrial genome

(2021) Christopher Jakubke et al.   Science Advances

DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair

(2020) Emeline Lawarée et al.   Cell Reports

A Putative Bet-Hedging Strategy Buffers Budding Yeast against Environmental Instability

(2020) Laura E. Bagamery et al.   CURRENT BIOLOGY

PINK1 Inhibits Local Protein Synthesis to Limit Transmission of Deleterious Mitochondrial DNA Mutations

(2019) Yi Zhang et al.   MOLECULAR CELL

Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline

(2019) Toby Lieber et al.   NATURE

Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1

(2019) Feng Ling et al.   Scientific Reports

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

(2019) Eduardo Silva Ramos et al.   PLoS Genetics

SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy

(2019) Arijit Ghosh et al.   Science Advances

A pipeline for multidimensional confocal analysis of mitochondrial morphology, function, and dynamics in pancreatic β-cells

(2019) Ahsen Chaudhry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Methods for imaging mammalian mitochondrial morphology: A prospective on MitoGraph

(2018) Megan C. Harwig et al.   ANALYTICAL BIOCHEMISTRY

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Autophagy balances mtDNA synthesis and degradation by DNA polymerase POLG during starvation

(2018) Tânia Catarina Medeiros et al.   JOURNAL OF CELL BIOLOGY

Linear mitochondrial DNA is rapidly degraded by components of the replication machinery

(2018) Viktoriya Peeva et al.   Nature Communications

The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions

(2018) Nadee Nissanka et al.   Nature Communications

The Cellular Mitochondrial Genome Landscape in Disease

(2018) Anne Hahn et al.   TRENDS IN CELL BIOLOGY

Mitochondria reorganization upon proliferation arrest predicts individual yeast cell fate

(2018) Damien Laporte et al.   eLife

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

A 5-mC Dot Blot Assay Quantifying the DNA Methylation Level of Chondrocyte Dedifferentiation In Vitro

(2017) Zhaofeng Jia et al.   Jove-Journal of Visualized Experiments

Assays to Monitor Autophagy in Saccharomyces cerevisiae

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The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

(2016) Gytis Jankevicius et al.   MOLECULAR CELL

Accurate concentration control of mitochondria and nucleoids

(2016) R. Jajoo et al.   SCIENCE

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

(2016) Samantha C. Lewis et al.   SCIENCE

Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion

(2015) Christof Osman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protecting the mitochondrial powerhouse

(2015) Morten Scheibye-Knudsen et al.   TRENDS IN CELL BIOLOGY

Mitochondrial dynamics and mitochondrial quality control

(2015) Hong-Min Ni et al.   Redox Biology

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant

(2014) Jahda H Hill et al.   NATURE GENETICS

Quality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity?

(2014) K. B. Busch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mitochondrial inheritance in yeast

(2013) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Persistent damage induces mitochondrial DNA degradation

(2013) Inna N. Shokolenko et al.   DNA REPAIR

An Algorithm to Automate Yeast Segmentation and Tracking

(2013) Andreas Doncic et al.   PLoS One

Inheritance of the fittest mitochondria in yeast

(2013) Jason D. Vevea et al.   TRENDS IN CELL BIOLOGY

The Maintenance of Mitochondrial DNA Integrity--Critical Analysis and Update

(2013) M. Alexeyev et al.   Cold Spring Harbor Perspectives in Biology

PINK1- and Parkin-mediated mitophagy at a glance

(2012) Seok Min Jin et al.   JOURNAL OF CELL SCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mitochondrial Network Size Scaling in Budding Yeast

(2012) S. M. Rafelski et al.   SCIENCE

Protein sliding and DNA denaturation are essential for DNA organization by human mitochondrial transcription factor A

(2012) Géraldine Farge et al.   Nature Communications

Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast

(2011) José Ricardo McFaline-Figueroa et al.   AGING CELL

Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction

(2011) T. A. Brown et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA repair in organelles: Pathways, organization, regulation, relevance in disease and aging

(2010) Pierre Boesch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial DNA mutations in disease and aging

(2010) Douglas C. Wallace   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Mitochondrial fission and fusion

(2010) Iain Scott et al.   Essays in Biochemistry

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress

(2010) Dan B. Swartzlander et al.   NUCLEIC ACIDS RESEARCH

Purification of Mitochondria from Yeast Cells

(2009) Christopher Gregg et al.   Jove-Journal of Visualized Experiments

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Molecular Machinery of Mitochondrial Fusion and Fission

(2008) Benedikt Westermann   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitophagy in Yeast Occurs through a Selective Mechanism

(2008) Tomotake Kanki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY