A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice

Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1)In Vitroby Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture

(2015) Theresa B. Kuhlenschmidt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preassembled Single-Stranded RNA–Argonaute Complexes: A Novel Method to Silence Genes inCryptosporidium

(2015) Alejandro Castellanos-Gonzalez et al.   JOURNAL OF INFECTIOUS DISEASES

The gatekeeper residue and beyond: homologous calcium-dependent protein kinases as drug development targets for veterinarian Apicomplexa parasites

(2014) KATELYN R. KEYLOUN et al.   PARASITOLOGY

A Novel Calcium-Dependent Protein Kinase Inhibitor as a Lead Compound for Treating Cryptosporidiosis

(2013) Alejandro Castellanos-Gonzalez et al.   JOURNAL OF INFECTIOUS DISEASES

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold

(2013) Zhongsheng Zhang et al.   ACS Medicinal Chemistry Letters

Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1

(2012) Zhongsheng Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Burden of disease from cryptosporidiosis

(2012) Debbie-Ann T. Shirley et al.   CURRENT OPINION IN INFECTIOUS DISEASES

The impoverished gut—a triple burden of diarrhoea, stunting and chronic disease

(2012) Richard L. Guerrant et al.   Nature Reviews Gastroenterology & Hepatology

The Potent Antiplasmodial Calmodulin-Antagonist Trifluoperazine Inhibits Plasmodium falciparum Calcium-Dependent Protein Kinase 4

(2011) Andrea Cavagnino et al.   PROTEIN AND PEPTIDE LETTERS

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

(2010) Kayode K Ojo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii

(2010) Ryan C. Murphy et al.   ACS Medicinal Chemistry Letters