Identification of Novel CD4+T Cell Subsets in the Target Tissue of Sjögren’s Syndrome and Their Differential Regulation by the Lymphotoxin/LIGHT Signaling Axis

BAFF overexpression increases lymphocytic infiltration in Sjögren's target tissue, but only inefficiently promotes ectopic B-cell differentiation

(2016) Jian Ding et al.   CLINICAL IMMUNOLOGY

Cytometry by time-of-flight immunophenotyping identifies a blood Sjögren's signature correlating with disease activity and glandular inflammation

(2016) Michael Mingueneau et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A review of salivary gland histopathology in primary Sjögren's syndrome with a focus on its potential as a clinical trials biomarker: Table 1

(2015) Benjamin A Fisher et al.   ANNALS OF THE RHEUMATIC DISEASES

A Distinct Function of Regulatory T Cells in Tissue Protection

(2015) Nicholas Arpaia et al.   CELL

Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice

(2015) Dmitriy Kolodin et al.   Cell Metabolism

The osteopontin transgenic mouse is a new model for Sjögren's syndrome

(2015) Sehba Husain-Krautter et al.   CLINICAL IMMUNOLOGY

Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation

(2015) John J. Worthington et al.   IMMUNITY

Reversible lacrimal gland-protective regulatory T-cell dysfunction underlies male-specific autoimmune dacryoadenitis in the non-obese diabetic mouse model of Sjögren syndrome

(2015) Scott M. Lieberman et al.   IMMUNOLOGY

A CD153+CD4+T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production

(2015) Suhail Tahir et al.   JOURNAL OF IMMUNOLOGY

Control of Regulatory T Cell Migration, Function, and Homeostasis

(2015) Daniel J. Campbell   JOURNAL OF IMMUNOLOGY

Identification of IL-18 and Th17 Cells in Salivary Glands of Patients with Sjogren's Syndrome, and Amplification of IL-17-Mediated Secretion of Inflammatory Cytokines from Salivary Gland Cells by IL-18

(2014) A. Sakai et al.   JOURNAL OF IMMUNOLOGY

Single-cell mass cytometry of TCR signaling: Amplification of small initial differences results in low ERK activation in NOD mice

(2014) Michael Mingueneau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Cytokine Expression and Regulatory Cells in Patients with Primary and Secondary Sjögren's Syndrome

(2014) J. Furuzawa-Carballeda et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Antibody-Secreting Cell Specificity in Labial Salivary Glands Reflects the Clinical Presentation and Serology in Patients With Sjögren's Syndrome

(2014) Jacen S. Maier-Moore et al.   Arthritis & Rheumatology

A Special Population of Regulatory T Cells Potentiates Muscle Repair

(2013) Dalia Burzyn et al.   CELL

Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor

(2013) Marton Keszei et al.   FASEB JOURNAL

Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor

(2013) Dietmar M.W. Zaiss et al.   IMMUNITY

Transient depletion of CD4+ CD25+regulatory T cells results in multiple autoimmune diseases in wild-type and B-cell-deficient NOD mice

(2013) Jason S. Ellis et al.   IMMUNOLOGY

Regulatory T cells in nonlymphoid tissues

(2013) Dalia Burzyn et al.   NATURE IMMUNOLOGY

Advances in understanding the pathogenesis of primary Sjögren's syndrome

(2013) Gaëtane Nocturne et al.   Nature Reviews Rheumatology

Characterization of a new regulatory CD4+ T cell subset in primary Sjogren's syndrome

(2013) A. Alunno et al.   RHEUMATOLOGY

Genome-Wide DNA Methylation Patterns in Naive CD4+ T Cells From Patients With Primary Sjögren's Syndrome

(2013) Nezam Altorok et al.   Arthritis & Rheumatology

Interleukin-21 contributes to germinal centre formation and immunoglobulin G4 production in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease

(2012) Takashi Maehara et al.   ANNALS OF THE RHEUMATIC DISEASES

Expression of IL-17, IL-23 and Their Receptors in Minor Salivary Glands of Patients with Primary Sjögren's Syndrome

(2012) Diana Mieliauskaite et al.   Clinical & Developmental Immunology

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients

(2012) T. Maehara et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

(2012) Daniela Cipolletta et al.   NATURE

Differentiation and function of Foxp3+ effector regulatory T cells

(2012) Erika Cretney et al.   TRENDS IN IMMUNOLOGY

Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome

(2011) Roy A Fava et al.   ARTHRITIS RESEARCH & THERAPY

Sjögren's syndrome: studying the disease in mice

(2011) Nicolas Delaleu et al.   ARTHRITIS RESEARCH & THERAPY

Salivary glands of primary Sjogren's syndrome patients express factors vital for plasma cell survival

(2011) Ewa A Szyszko et al.   ARTHRITIS RESEARCH & THERAPY

A Role for Lymphotoxin in Primary Sjogren's Disease

(2010) L. Shen et al.   JOURNAL OF IMMUNOLOGY

The numbers of Foxp3 + Treg cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sjögren's syndrome

(2009) M. Sarigul et al.   LUPUS

Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren syndrome in salivary glands of non-obese diabetic mice

(2009) Margaret K Gatumu et al.   ARTHRITIS RESEARCH & THERAPY

Foxp3+ T-Regulatory Cells in Sjögren's Syndrome

(2008) Maria I. Christodoulou et al.   AMERICAN JOURNAL OF PATHOLOGY