TGF-β Signaling in Dendritic Cells Governs Colonic Homeostasis by Controlling Epithelial Differentiation and the Luminal Microbiota

Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease

(2015) Giovanni Monteleone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation

(2014) Yoshiyuki Goto et al.   IMMUNITY

Development and Function of Dendritic Cell Subsets

(2014) Alexander Mildner et al.   IMMUNITY

CCR2+CD103− intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells

(2014) C L Scott et al.   Mucosal Immunology

The murine appendiceal microbiome is altered in spontaneous colitis and its pathological progression

(2014) Sultan Alkadhi et al.   Gut Pathogens

Molecular Control of Steady-State Dendritic Cell Maturation and Immune Homeostasis

(2013) Gianna Elena Hammer et al.   Annual Review of Immunology

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

(2013) Malin E V Johansson et al.   GUT

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

(2013) M Zaeem Cader et al.   GUT

Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation

(2013) Julia Farache et al.   IMMUNITY

Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut

(2013) S. E. Winter et al.   SCIENCE

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis

(2012) Dirk Lievens et al.   EUROPEAN HEART JOURNAL

Dendritic Cell-Specific Disruption of TGF-  Receptor II Leads to Altered Regulatory T Cell Phenotype and Spontaneous Multiorgan Autoimmunity

(2012) R. Ramalingam et al.   JOURNAL OF IMMUNOLOGY

Deletion of TGF-  signaling in myeloid cells enhances their anti-tumorigenic properties

(2012) S. V. Novitskiy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells

(2012) V Cerovic et al.   Mucosal Immunology

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Small intestine CD11c+ CD8+ T cells suppress CD4+ T cell-induced immune colitis

(2011) Daisuke Fujiwara et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Role of Notch signaling in colon homeostasis and carcinogenesis

(2011) Shingo Miyamoto et al.   CANCER SCIENCE

New IBD genetics: common pathways with other diseases

(2011) C. W. Lees et al.   GUT

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Balancing acts: the role of TGF-β in the mucosal immune system

(2011) Joanne E. Konkel et al.   TRENDS IN MOLECULAR MEDICINE

Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine

(2010) M. Sakata-Yanagimoto et al.   BLOOD

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

GM-CSF-Facilitated Dendritic Cell Recruitment and Survival Govern the Intestinal Mucosal Response to a Mouse Enteric Bacterial Pathogen

(2010) Yoshihiro Hirata et al.   Cell Host & Microbe

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis

(2009) Michael Gersemann et al.   DIFFERENTIATION

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Commensals, Bacterial Pathogens and Intestinal Inflammation: An Intriguing Ménage à Trois

(2008) Thierry Pédron et al.   Cell Host & Microbe

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Blockade of transforming growth factor   upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in the human gut mucosa

(2008) A. Di Sabatino et al.   GUT

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA