Early Terminal Complement Blockade and C6 Deficiency Are Protective in EnterohemorrhagicEscherichia coli–Infected Mice

Activation of the alternative pathway of complement during the acute phase of typical haemolytic uraemic syndrome

(2015) J. R. Ferraris et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Shiga Toxin–Induced Complement-Mediated Hemolysis and Release of Complement-Coated Red Blood Cell–Derived Microvesicles in Hemolytic Uremic Syndrome

(2015) Ida Arvidsson et al.   JOURNAL OF IMMUNOLOGY

The Serine Protease Pic From Enteroaggregative Escherichia coli Mediates Immune Evasion by the Direct Cleavage of Complement Proteins

(2015) Afonso G. Abreu et al.   JOURNAL OF INFECTIOUS DISEASES

A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles

(2015) Anne-lie Ståhl et al.   PLoS Pathogens

Eculizumab treatment for rescue of renal function in IgA nephropathy

(2014) Therese Rosenblad et al.   PEDIATRIC NEPHROLOGY

Role of Complement in Enterohemorrhagic Escherichia coli–Induced Hemolytic Uremic Syndrome

(2014) Reinhard Würzner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy

(2013) B. C. Lee et al.   BLOOD

Interaction of Shiga Toxin with the A-domains and Multimers of von Willebrand Factor

(2013) Nathan C. Lo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement Activation Associated with ADAMTS13 Deficiency in Human and Murine Thrombotic Microangiopathy

(2013) R. Tati et al.   JOURNAL OF IMMUNOLOGY

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

(2013) Nancy A. Turner et al.   PLoS One

An Outbreak of Shiga Toxin-Producing Escherichia coli O104:H4 Hemolytic Uremic Syndrome in Germany: Presentation and Short-term Outcome in Children

(2012) S. Loos et al.   CLINICAL INFECTIOUS DISEASES

The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin–associated hemolytic uremic syndrome in humans and mice

(2012) Tania N. Petruzziello-Pellegrini et al.   JOURNAL OF CLINICAL INVESTIGATION

Management of Shiga toxin-associated Escherichia coli-induced haemolytic uraemic syndrome: randomized clinical trials are needed

(2012) D. Karpman   NEPHROLOGY DIALYSIS TRANSPLANTATION

Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic–uraemic syndrome: an analysis of the German STEC-HUS registry

(2012) Jan T. Kielstein et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults

(2012) K. Weissenborn et al.   NEUROLOGY

The Antimicrobial Peptide Cathelicidin Protects Mice from Escherichia coli O157:H7-Mediated Disease

(2012) Milan Chromek et al.   PLoS One

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

(2012) J. Menne et al.   BMJ-British Medical Journal

Anti-Complement Component C5 mAb Synergizes with CTLA4Ig to Inhibit Alloreactive T cells and Prolong Cardiac Allograft Survival in Mice

(2011) H. Raedler et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome

(2011) A.-l. Stahl et al.   BLOOD

Cross-Reactive Protection against Enterohemorrhagic Escherichia coli Infection by Enteropathogenic E. coli in a Mouse Model

(2011) Carla Calderon Toledo et al.   INFECTION AND IMMUNITY

Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice

(2011) N. K. Banda et al.   JOURNAL OF IMMUNOLOGY

Alternative Pathway Activation of Complement by Shiga Toxin Promotes Exuberant C3a Formation That Triggers Microvascular Thrombosis

(2011) M. Morigi et al.   JOURNAL OF IMMUNOLOGY

Eculizumab in Severe Shiga-Toxin–Associated HUS

(2011) Anne-Laure Lapeyraque et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute Neurological Involvement in Diarrhea-Associated Hemolytic Uremic Syndrome

(2010) S. Nathanson et al.   Clinical Journal of the American Society of Nephrology

EspP, a Serine Protease of Enterohemorrhagic Escherichia coli, Impairs Complement Activation by Cleaving Complement Factors C3/C3b and C5

(2010) D. Orth et al.   INFECTION AND IMMUNITY

The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5

(2010) E. G. de Jorge et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Clinical Relevance of Shiga Toxin Concentrations in the Blood of Patients With Hemolytic Uremic Syndrome

(2010) Maurizio Brigotti et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Intestinal damage in enterohemorrhagic Escherichia coli infection

(2010) Zivile D. Békássy et al.   PEDIATRIC NEPHROLOGY

Alternative Pathway of Complement in Children with Diarrhea-Associated Hemolytic Uremic Syndrome

(2009) J. M. Thurman et al.   Clinical Journal of the American Society of Nephrology

Shiga Toxin Activates Complement and Binds Factor H: Evidence for an Active Role of Complement in Hemolytic Uremic Syndrome

(2009) Dorothea Orth et al.   JOURNAL OF IMMUNOLOGY

The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice

(2009) Ruth D. Lewis et al.   MOLECULAR IMMUNOLOGY

Shiga Toxin and Lipopolysaccharide Induce Platelet-Leukocyte Aggregates and Tissue Factor Release, a Thrombotic Mechanism in Hemolytic Uremic Syndrome

(2009) Anne-lie Ståhl et al.   PLoS One

Shiga Toxin-Mediated Disease in MyD88-Deficient Mice Infected with Escherichia coli O157:H7

(2008) Carla Calderon Toledo et al.   AMERICAN JOURNAL OF PATHOLOGY