Complement Protein C1q Enhances Macrophage Foam Cell Survival and Efferocytosis

Macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins are modulated by complement protein C1q

(2016) Minh-Minh Ho et al.   ATHEROSCLEROSIS

Complement Component C1q Programs a Pro-Efferocytic Phenotype while Limiting TNFα Production in Primary Mouse and Human Macrophages

(2016) Holly J. Hulsebus et al.   Frontiers in Immunology

The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis

(2015) Anders Hovland et al.   ATHEROSCLEROSIS

Cholesterol crystal induced arterial inflammation and destabilization of atherosclerotic plaque

(2015) Abed Janoudi et al.   EUROPEAN HEART JOURNAL

Pro-inflammatory monocyte-macrophage polarization imbalance in human hypercholesterolemia and atherosclerosis

(2014) Gian Paolo Fadini et al.   ATHEROSCLEROSIS

Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins

(2014) Weston Spivia et al.   INFLAMMATION RESEARCH

Murine Low-Density Lipoprotein Receptor-Related Protein 1 (LRP) Is Required for Phagocytosis of Targets Bearing LRP Ligands but Is Not Required for C1q-Triggered Enhancement of Phagocytosis

(2014) A. P. Lillis et al.   JOURNAL OF IMMUNOLOGY

Complement Protein C1q and Adiponectin Stimulate Mer Tyrosine Kinase-Dependent Engulfment of Apoptotic Cells through a Shared Pathway

(2014) Manuel D. Galvan et al.   Journal of Innate Immunity

Complement, C1q, and C1q-Related Molecules Regulate Macrophage Polarization

(2014) Suzanne S. Bohlson et al.   Frontiers in Immunology

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

Complement Component C1q Regulates Macrophage Expression of Mer Tyrosine Kinase To Promote Clearance of Apoptotic Cells

(2012) M. D. Galvan et al.   JOURNAL OF IMMUNOLOGY

Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

(2012) M. E. Benoit et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis

(2011) Christopher M. Scull et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Complement Protein C1q-Mediated Neuroprotection Is Correlated with Regulation of Neuronal Gene and MicroRNA Expression

(2011) M. E. Benoit et al.   JOURNAL OF NEUROSCIENCE

The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques

(2010) Hiroto Tsukano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Complement Protein C1q Recognizes Enzymatically Modified Low-Density Lipoprotein through Unesterified Fatty Acids Generated by Cholesterol Esterase

(2010) Adrienn Biro et al.   BIOCHEMISTRY

Innate Immune Proteins C1q and Mannan-Binding Lectin Enhance Clearance of Atherogenic Lipoproteins by Human Monocytes and Macrophages

(2010) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

Macrophage Response to Apoptotic Cells Varies with the Apoptotic Trigger and Is Not Altered by a Deficiency in LRP Expression

(2010) Ana Kozmar et al.   Journal of Innate Immunity

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Macrophage Apoptosis in Advanced Atherosclerosis

(2009) Ira Tabas et al.   Annals of the New York Academy of Sciences

Macrophage Apoptosis in Atherosclerosis: Consequences on Plaque Progression and the Role of Endoplasmic Reticulum Stress

(2009) Ira Tabas   ANTIOXIDANTS & REDOX SIGNALING

Macrophage Diversity and Polarization in Atherosclerosis

(2009) Alberto Mantovani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice

(2009) Lianne S.M. Boesten et al.   ATHEROSCLEROSIS

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Innate immune signals in atherosclerosis

(2009) Anna M. Lundberg et al.   CLINICAL IMMUNOLOGY

C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

(2009) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production

(2009) Deborah A. Fraser et al.   JOURNAL OF NEUROCHEMISTRY

Metalloproteinase Expression in Monocytes and Macrophages and its Relationship to Atherosclerotic Plaque Instability

(2008) Andrew C. Newby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mertk Receptor Mutation Reduces Efferocytosis Efficiency and Promotes Apoptotic Cell Accumulation and Plaque Necrosis in Atherosclerotic Lesions of Apoe −/− Mice

(2008) Edward Thorp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signal Transducer and Activator of Transcription-1 Is Critical for Apoptosis in Macrophages Subjected to Endoplasmic Reticulum Stress In Vitro and in Advanced Atherosclerotic Lesions In Vivo

(2008) Wah-Seng Lim et al.   CIRCULATION

Increased Cellular Free Cholesterol in Macrophage-specificAbca1Knock-out Mice Enhances Pro-inflammatory Response of Macrophages

(2008) Xuewei Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY