Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes

Nardilysin-Dependent Proteolysis of Cell-Associated VTCN1 (B7-H4) Marks Type 1 Diabetes Development

(2014) I. A. Radichev et al.   DIABETES

Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes

(2014) Shoko Ishizu-Higashi et al.   PLoS One

Autoimmune Diabetes Is Suppressed by Treatment with Recombinant Human Tissue Kallikrein-1

(2014) Lilia Maneva-Radicheva et al.   PLoS One

Serum B7-H4 expression is a significant prognostic indicator for patients with gastric cancer

(2014) Hongbing Shi et al.   World Journal of Surgical Oncology

Expression of co-stimulatory molecule B7-H4 in patients suffering from rheumatoid arthritis

(2013) Lujun Chen et al.   IMMUNOLOGY LETTERS

B7-H4Ig inhibits mouse and human T-cell function and treats EAE via IL-10/Treg-dependent mechanisms

(2013) Joseph R. Podojil et al.   JOURNAL OF AUTOIMMUNITY

B7-H4 Expression in Normal and Diseased Human Islet β Cells

(2013) Susan S.C. Cheung et al.   PANCREAS

Cytotoxic Mechanisms Employed by Mouse T Cells to Destroy Pancreatic  -Cells

(2012) V. Varanasi et al.   DIABETES

B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells

(2012) J. S. Lee et al.   JOURNAL OF IMMUNOLOGY

Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival

(2012) Xiaojie Wang et al.   Islets

Induced expression of B7-H4 on the surface of lung cancer cell by the tumor-associated macrophages: A potential mechanism of immune escape

(2011) Cheng Chen et al.   CANCER LETTERS

B7-H4 Induces Donor-Specific Tolerance in Mouse Islet Allografts

(2011) Xiaojie Wang et al.   CELL TRANSPLANTATION

The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival

(2011) Changjun He et al.   Clinical & Developmental Immunology

B7-H4 Expression in Human Melanoma: Its Association with Patients' Survival and Antitumor Immune Response

(2011) D. Quandt et al.   CLINICAL CANCER RESEARCH

Early Treatment of NOD Mice With B7-H4 Reduces the Incidence of Autoimmune Diabetes

(2011) X. Wang et al.   DIABETES

Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity

(2011) Joyce Wei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes

(2010) Jan H Kessler et al.   NATURE IMMUNOLOGY

Local Expression of B7-H4 by Recombinant Adenovirus Transduction in Mouse Islets Prolongs Allograft Survival

(2010) Xiaojie Wang et al.   TRANSPLANTATION

Measurement of CD8+T Cell Responses in Human Type 1 Diabetes

(2009) Emanuela Martinuzzi et al.   Annals of the New York Academy of Sciences

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Transcriptome Analysis Describing New Immunity and Defense Genes in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients

(2009) Vitor Hugo Teixeira et al.   PLoS One

B7-H4 transfection prolongs β-cell graft survival

(2009) Chun-lei Yuan et al.   TRANSPLANT IMMUNOLOGY

Potential Role of Decoy B7-H4 in the Pathogenesis of Rheumatoid Arthritis: A Mouse Model Informed by Clinical Data

(2009) Takeshi Azuma et al.   PLOS MEDICINE